| Definition | Burkholderia mallei NCTC 10247 chromosome II, complete genome. |
|---|---|
| Accession | NC_009079 |
| Length | 2,352,693 |
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The map label for this gene is paaG [H]
Identifier: 126446349
GI number: 126446349
Start: 1835329
End: 1836120
Strand: Direct
Name: paaG [H]
Synonym: BMA10247_A1903
Alternate gene names: 126446349
Gene position: 1835329-1836120 (Clockwise)
Preceding gene: 126445826
Following gene: 126446935
Centisome position: 78.01
GC content: 66.29
Gene sequence:
>792_bases ATGTCCTACCAGACGATTCGCATCGAAATCGATCAGGCGGCACAGATCGCGACGATCACGCTCGATCGCCCCGACAAGCT CAACAGCTTCACGCGCGACATGCATCGCGAACTGCAGTCGGCGCTCGACGACGTGCAGGCCGCGAACGCACGCGCCCTGG TTCTCACCGGCGCAGGACGCGGCTTCTGCGCAGGCCAGGATCTCGCCGATCTCGACTTCACGCCGGGGGCGATGACCGAT CTCGGCGAGGTGATCGAAGCGCATTTCAATCCGCTCGTTCGCCGCCTGCAAGCGCTGCCGCTGCCCGTCATCGCCGCCGT GAACGGCACCGCGGCGGGCGCCGGCGCCAACCTCGCGTTCGCCTGCGATCTCGTCATCGCGGCGAAATCGAGCAGCTTCA TTCAGTCGTTCGTGAAAATCGGCCTCGTTCCGGATTCCGGCGGCACGTGGTTCCTGCCGCAGCGCGTCGGCTTCGCCCGT GCGCTCGGGCTCGCACTGACCGGCGACAAACTGAGTGCCGAACAAGCCGAGCGTTGGGGACTCGTGTGGCGGGTCGTCGA CGATGCCGAACTCGCGGGCGCCGCCGCACAACTCGCCCGAGAACTTGCGCAACAGCCGACGCGGGCGATCGCGGCGATCA AGCAGGCGATGCGTGCGAGCCTCACCCATACGCTCGACCAGCAGCTCGATCTCGAACGCGATCTTCAGCGCGAGCTCGGG CAATCGTACGACTACGCGGAAGGGGTGCGCGCGTTCATCGAAAAGCGCGCCCCTCGCTTCGAAGGACGCTGA
Upstream 100 bases:
>100_bases GGCGTCGGCCAGGGCATCGCGATCGCGATCGAGCGCGTATAAGCCGGCCCGCGGACGAAGGACGCATCCCGTTCATTTCG AAGAGGCAAGGAGACAGCCG
Downstream 100 bases:
>100_bases GATGGCCGCACGCTCTCCCGAACGCTCGCCAACGGCGACCGCAGAACGCTCCGCCGAAGCGCTCGCCCGCGCAACCGCCG AAGCAATGTACGCCGCGGAC
Product: enoyl-CoA hydratase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 263; Mature: 262
Protein sequence:
>263_residues MSYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGRGFCAGQDLADLDFTPGAMTD LGEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAFACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFAR ALGLALTGDKLSAEQAERWGLVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELG QSYDYAEGVRAFIEKRAPRFEGR
Sequences:
>Translated_263_residues MSYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGRGFCAGQDLADLDFTPGAMTD LGEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAFACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFAR ALGLALTGDKLSAEQAERWGLVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELG QSYDYAEGVRAFIEKRAPRFEGR >Mature_262_residues SYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGRGFCAGQDLADLDFTPGAMTDL GEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAFACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFARA LGLALTGDKLSAEQAERWGLVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELGQ SYDYAEGVRAFIEKRAPRFEGR
Specific function: Could possibly oxidize fatty acids using specific components [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=33.1983805668016, Blast_Score=127, Evalue=1e-29, Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=29.6992481203008, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI31542718, Length=261, Percent_Identity=28.735632183908, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI45643119, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI260275230, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI260274832, Length=204, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI221136756, Length=238, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI221136753, Length=238, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI221307494, Length=238, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI20127408, Length=179, Percent_Identity=30.7262569832402, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI25453481, Length=243, Percent_Identity=23.8683127572016, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI51538573, Length=243, Percent_Identity=23.8683127572016, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI4757968, Length=243, Percent_Identity=23.8683127572016, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI49355787, Length=243, Percent_Identity=23.8683127572016, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI157694516, Length=224, Percent_Identity=27.2321428571429, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI213417737, Length=224, Percent_Identity=27.2321428571429, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI37594469, Length=190, Percent_Identity=31.0526315789474, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI37594471, Length=190, Percent_Identity=31.0526315789474, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI4757966, Length=237, Percent_Identity=24.0506329113924, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI51538581, Length=237, Percent_Identity=24.0506329113924, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI116235487, Length=231, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI68989263, Length=179, Percent_Identity=29.608938547486, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI157694520, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787660, Length=250, Percent_Identity=58, Blast_Score=263, Evalue=8e-72, Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=35.2713178294574, Blast_Score=129, Evalue=2e-31, Organism=Escherichia coli, GI221142681, Length=274, Percent_Identity=37.2262773722628, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI87082183, Length=271, Percent_Identity=29.520295202952, Blast_Score=111, Evalue=6e-26, Organism=Escherichia coli, GI1788597, Length=262, Percent_Identity=31.2977099236641, Blast_Score=91, Evalue=9e-20, Organism=Escherichia coli, GI1788682, Length=202, Percent_Identity=31.6831683168317, Blast_Score=84, Evalue=6e-18, Organism=Escherichia coli, GI1790281, Length=189, Percent_Identity=29.6296296296296, Blast_Score=66, Evalue=3e-12, Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=34.5381526104418, Blast_Score=143, Evalue=7e-35, Organism=Caenorhabditis elegans, GI17554946, Length=262, Percent_Identity=31.2977099236641, Blast_Score=128, Evalue=3e-30, Organism=Caenorhabditis elegans, GI17549921, Length=233, Percent_Identity=28.3261802575107, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17535521, Length=257, Percent_Identity=27.2373540856031, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17536985, Length=266, Percent_Identity=27.0676691729323, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560910, Length=253, Percent_Identity=26.4822134387352, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17540306, Length=260, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17534483, Length=225, Percent_Identity=26.2222222222222, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17540714, Length=175, Percent_Identity=30.8571428571429, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI25144276, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17508951, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17508953, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17558304, Length=227, Percent_Identity=27.3127753303965, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI25141363, Length=204, Percent_Identity=30.3921568627451, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI20129971, Length=261, Percent_Identity=30.6513409961686, Blast_Score=135, Evalue=4e-32, Organism=Drosophila melanogaster, GI24653477, Length=261, Percent_Identity=30.6513409961686, Blast_Score=135, Evalue=4e-32, Organism=Drosophila melanogaster, GI24653139, Length=261, Percent_Identity=32.9501915708812, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI19922422, Length=250, Percent_Identity=28, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24654903, Length=256, Percent_Identity=25.78125, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI19920382, Length=252, Percent_Identity=30.5555555555556, Blast_Score=92, Evalue=5e-19, Organism=Drosophila melanogaster, GI21357171, Length=257, Percent_Identity=28.0155642023346, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24650670, Length=217, Percent_Identity=29.0322580645161, Blast_Score=76, Evalue=2e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001753 - InterPro: IPR011968 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.17 [H]
Molecular weight: Translated: 28401; Mature: 28269
Theoretical pI: Translated: 5.14; Mature: 5.14
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGR CCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC GFCAGQDLADLDFTPGAMTDLGEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAF CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHH ACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFARALGLALTGDKLSAEQAERWG EEHHHEECCCHHHHHHHHHHCCEECCCCCEECHHHHHHHHHHHHHCCCCCCCHHHHHHCC LVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELG EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC QSYDYAEGVRAFIEKRAPRFEGR CCCCHHHHHHHHHHHCCCCCCCC >Mature Secondary Structure SYQTIRIEIDQAAQIATITLDRPDKLNSFTRDMHRELQSALDDVQAANARALVLTGAGR CCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC GFCAGQDLADLDFTPGAMTDLGEVIEAHFNPLVRRLQALPLPVIAAVNGTAAGAGANLAF CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHH ACDLVIAAKSSSFIQSFVKIGLVPDSGGTWFLPQRVGFARALGLALTGDKLSAEQAERWG EEHHHEECCCHHHHHHHHHHCCEECCCCCEECHHHHHHHHHHHHHCCCCCCCHHHHHHCC LVWRVVDDAELAGAAAQLARELAQQPTRAIAAIKQAMRASLTHTLDQQLDLERDLQRELG EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC QSYDYAEGVRAFIEKRAPRFEGR CCCCHHHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9748275; 9097039; 9278503; 10766858 [H]