Click here to switch to the map view.

The map label for this gene is paaK [H]

Identifier: 126446935

GI number: 126446935

Start: 1836634

End: 1837932

Strand: Direct

Name: paaK [H]

Synonym: BMA10247_A1905

Alternate gene names: 126446935

Gene position: 1836634-1837932 (Clockwise)

Preceding gene: 126446349

Following gene: 126447297

Centisome position: 78.07

GC content: 65.82

Gene sequence:

>1299_bases
ATGGCAACCTCGCTTCCGCTCGACCCGATCGAACGAGCGAGCCGCGACGAACTGCTCGCGCTTCAGCTCGACCGCCTGAA
ATGGTCACTCGCCCACGCGTACGAGAACTCGCCCGTCTATCGGCGCAAGTTCGACGAGGCGGGCGTGCACCCGGCCGATC
TGAAAACGCTTGCGGATCTGAGCCGCTTTCCGTTCACGACGAAGAACGATCTGCGCGACAACTATCCGTTCGGCATGTTC
GCCGTGCCGCAGGAGCGCATCTCGCGCATCCACGCTTCGTCAGGCACGACGGGCAAGCCGACGGTGGTCGGCTATACCGC
GCGGGACATCGATACCTGGGCGGGCCTCGTCGCACGCTCGATCCGCGCGGCGGGCGCGCGGCCGGGCGACAAGGTGCATG
TGAGCTACGGCTACCGCCTCTTCACGGGCGGCCTGGGCGCGCATTACGGCGCCGAGCGGGCCGGGCTGACGGTGATCCCG
TTCGGCGGCGGCCAGACCGAAAAGCAGGTGCAACTGATCCAGGACTTCCGGCCCGACATCATCATGGTGACGCCCAGCTA
CATGCTGTCGATCGCCGACGAAATGGAACGTCAGCACCTCGATCCCGCCCAGTGCTCGCTGCGAATCGGCATCTTCGGCG
CGGAACCGTGGACCAACGACATGCGTGTCGCAATCGAGCAGCGCATGGGCATCGACGCCGTCGACATCTATGGGCTCTCC
GAGGTGATCGGCCCGGGCGTCGCATCGGAGTGCGTCGAAACGAAGGACGGCCCGACGATCTGGGAAGATCACTTCTACCC
CGAGATCATCGATCCCGACACCGGCGAAGTGCTGCCGGACGGCGCATTCGGCGAACTCGTGTTCACGTCGCTCACGAAGG
AAGCGCTGCCGATCGTCCGCTACCGGACCCGCGACCTCACCCGCCTGCTGCCCGGCACCGCGCGTACGATGCGCAGGATG
GAAAAAATCACCGGCCGTTCGGACGACATGATGATCGTGCGCGGCGTGAACGTGTTCCCGACCCAGCTCGAAGAGCAATT
GCTCAAGCAGCGTGCGCTCGCGCCTCACTATCAGGTGGTGCTGACGAAGGACGGGCCGCTCGACGTGCTGACGCTCAACG
TCGAGCCCTGCCCGGAGACGGCGCCGGATGCGGCCGCGATCGACGCCGCACGCCGCGCGCTCGCGCACGACATCAAATCG
CTGATTGGCGTGACGGCGATCATCAACGTGTTGCCCGTCAACGGCATCGAGCGCTCGGTCGGCAAGGCGAGACGAATCGT
CGACAAGCGGCGGCCGTGA

Upstream 100 bases:

>100_bases
GTCGCGATGTTCCGCGGCAAGTCGACTCAAATCAAAGGGACGGTGATCCCTGTAGACCGTTAGCGTTCACGCACGCTCAC
ATAAATATATTGGAGACATC

Downstream 100 bases:

>100_bases
CGTTTCGCGCATGGCGGCTGGGCAGCCCGCACGTGTGCGCGCTTGCGGGCCCGGGCCGCCTGAGGAAAGATCGCCGCGCG
GGGCGCGGCGGCGCGCATCA

Product: phenylacetate-coenzyme A ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADLSRFPFTTKNDLRDNYPFGMF
AVPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARSIRAAGARPGDKVHVSYGYRLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EVIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVVLTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKS
LIGVTAIINVLPVNGIERSVGKARRIVDKRRP

Sequences:

>Translated_432_residues
MATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADLSRFPFTTKNDLRDNYPFGMF
AVPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARSIRAAGARPGDKVHVSYGYRLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EVIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVVLTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKS
LIGVTAIINVLPVNGIERSVGKARRIVDKRRP
>Mature_431_residues
ATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADLSRFPFTTKNDLRDNYPFGMFA
VPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARSIRAAGARPGDKVHVSYGYRLFTGGLGAHYGAERAGLTVIPF
GGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLSE
VIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVRYRTRDLTRLLPGTARTMRRME
KITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVVLTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKSL
IGVTAIINVLPVNGIERSVGKARRIVDKRRP

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=436, Percent_Identity=64.2201834862385, Blast_Score=581, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47766; Mature: 47635

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADL
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
SRFPFTTKNDLRDNYPFGMFAVPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARS
HHCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARPGDKVHVSYGYRLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHCCCCCCCEEEEEECEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EEECHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHCCHH
EVIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVR
HHHCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKSLIGVTAIINVLPVNGIERSV
EECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GKARRIVDKRRP
HHHHHHHHCCCC
>Mature Secondary Structure 
ATSLPLDPIERASRDELLALQLDRLKWSLAHAYENSPVYRRKFDEAGVHPADLKTLADL
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
SRFPFTTKNDLRDNYPFGMFAVPQERISRIHASSGTTGKPTVVGYTARDIDTWAGLVARS
HHCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARPGDKVHVSYGYRLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHCCCCCCCEEEEEECEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADEMERQHLDPAQCSLRIGIFGAEPWTNDMRVAIEQRMGIDAVDIYGLS
EEECHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHCCHH
EVIGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGAFGELVFTSLTKEALPIVR
HHHCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIVRGVNVFPTQLEEQLLKQRALAPHYQVV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKDGPLDVLTLNVEPCPETAPDAAAIDAARRALAHDIKSLIGVTAIINVLPVNGIERSV
EECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GKARRIVDKRRP
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]