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The map label for this gene is atoC [H]

Identifier: 126446333

GI number: 126446333

Start: 2199800

End: 2201170

Strand: Reverse

Name: atoC [H]

Synonym: BMA10247_A2268

Alternate gene names: 126446333

Gene position: 2201170-2199800 (Counterclockwise)

Preceding gene: 126446591

Following gene: 126446255

Centisome position: 93.56

GC content: 68.42

Gene sequence:

>1371_bases
ATGCCCTACATTCTCATCGTCGAGGATGATGCGGACACGCGCGACATGCTTTGCGCTCTGGCGCATACCCAGCAGCTCGC
CTGCGATGCGGCTGCGACGCTGGAGGAGGCGCGCGCGCTGATCGCGACGCACACGCCGGATCTGGTGCTGTGCGATCTCG
TTCTGCCGGACGGCAACGGCATGGATCTGTTCGACGAGCTGCCCAAGGGCGCGCACGTCGAGATGGTGCTGACGACAGGA
CACGCGAGCCTCGAAACCGCGATCGACGCGCTGCGAAGAGGCGCGACCGATTATCTGGTGAAGCCGCTGAACATGCAGCG
GCTGAACAGCATCTTCGCGCGCGTGCCGCGCACCGGCGTGCTGCACGAGGAGATCGCCGCGCTGCGCTCGGAGCTGCAGC
GGCTCGGCCGCTTCGGCAGGATGCTCGGGCGCTCGCCCGTGATGCAGACGATGTACGACGCGATCGGCCGCGTCGCGGGC
ACCGAGGCGTCCGTGCTGCTGATGGGTGAATCGGGCACCGGCAAGGAGCTCGCCGCGCAGACGATCCACGATCTGAGCCT
GCGCCGCAAGGGGCCGTTTCTCGCGGTCAACTGCGGCGCGATCGCGGCGAACCTCGTCGAGAGCGAGATGTTCGGCCACG
ACCGCGGCAGCTTCACCGGCGCGGATCGTCAGCACAAGGGTTTCTTCGAGCGTGCGGACGGCGGCACGCTGTTCCTCGAC
GAGATCACCGAGATGCCCGTCGAATCGCAGGTGAAGCTGCTGCGCGTGCTCGAGACGGGGCGGCTCACGCGGCTCGGCTC
CGCGCGCGAGCTCGACGTCGACGTGCGGATCGTCGCCGCGACGAACCTCGACCCGGAAGCCGCGATGGCGGACGGCAAGC
TGCGCCCGGACCTGTACCACCGGATCAATGTGTTCCCGATCACGCTGCCGCCGCTGCGCGCGCGCGGCGACGACATTCCG
ATGCTCGCCGAGGCGTTCCTGCGGCAGCTCGGCGAGGACAGCGGGCGCAAGATGCGCTTCTCGGCGTCCGCGCTCGCCGC
GCTTGCCGAATACGACTGGCCGGGCAACGTGCGCGAGCTGCGCAACTTCGTGCAGCGCGCCTGCATTTTCAACGACGGCG
AGGTGATCGACACGCTGCCGCCGCCGATCATGGACGAAGTGGCGAGCGAGCCGGGCGACGACGGCGACGCGGTGACGGTG
CCGTTCGGCACGTCGCTCGAGGAAGTCGACAGGCGGATCATTCTCGGCACGCTCGCGCAGTGCGGCGGCGTGAAGACGCA
CGCGGCCGAGGTGCTCGACATCAGCCTGAAGACGATCTACAACCGGCTCGCGCAGCTCGAGGCGGAGGGGGACGACAAGA
CGAAGCGATGA

Upstream 100 bases:

>100_bases
CGCACATCGGCCGGCATCGTTCGGCCGCCTAATCGGATATGCGCCGGCATGCGGGCTCGTTCATCGCTTGCGCCGGCGCG
CAACGGACGAAGGAGCTCGA

Downstream 100 bases:

>100_bases
AGGCGCGCGCGATGCCGATGCGGCTACGGCCGCTGCCGCCGCGCCTGCCGGCGCGCGAGCCGATCGGCGGCTTCGACCAC
GCGCCGCATCGCGTCGACGT

Product: sigma-54 dependent DNA-binding response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MPYILIVEDDADTRDMLCALAHTQQLACDAAATLEEARALIATHTPDLVLCDLVLPDGNGMDLFDELPKGAHVEMVLTTG
HASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTGVLHEEIAALRSELQRLGRFGRMLGRSPVMQTMYDAIGRVAG
TEASVLLMGESGTGKELAAQTIHDLSLRRKGPFLAVNCGAIAANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFLD
EITEMPVESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNLDPEAAMADGKLRPDLYHRINVFPITLPPLRARGDDIP
MLAEAFLRQLGEDSGRKMRFSASALAALAEYDWPGNVRELRNFVQRACIFNDGEVIDTLPPPIMDEVASEPGDDGDAVTV
PFGTSLEEVDRRIILGTLAQCGGVKTHAAEVLDISLKTIYNRLAQLEAEGDDKTKR

Sequences:

>Translated_456_residues
MPYILIVEDDADTRDMLCALAHTQQLACDAAATLEEARALIATHTPDLVLCDLVLPDGNGMDLFDELPKGAHVEMVLTTG
HASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTGVLHEEIAALRSELQRLGRFGRMLGRSPVMQTMYDAIGRVAG
TEASVLLMGESGTGKELAAQTIHDLSLRRKGPFLAVNCGAIAANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFLD
EITEMPVESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNLDPEAAMADGKLRPDLYHRINVFPITLPPLRARGDDIP
MLAEAFLRQLGEDSGRKMRFSASALAALAEYDWPGNVRELRNFVQRACIFNDGEVIDTLPPPIMDEVASEPGDDGDAVTV
PFGTSLEEVDRRIILGTLAQCGGVKTHAAEVLDISLKTIYNRLAQLEAEGDDKTKR
>Mature_455_residues
PYILIVEDDADTRDMLCALAHTQQLACDAAATLEEARALIATHTPDLVLCDLVLPDGNGMDLFDELPKGAHVEMVLTTGH
ASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTGVLHEEIAALRSELQRLGRFGRMLGRSPVMQTMYDAIGRVAGT
EASVLLMGESGTGKELAAQTIHDLSLRRKGPFLAVNCGAIAANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFLDE
ITEMPVESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNLDPEAAMADGKLRPDLYHRINVFPITLPPLRARGDDIPM
LAEAFLRQLGEDSGRKMRFSASALAALAEYDWPGNVRELRNFVQRACIFNDGEVIDTLPPPIMDEVASEPGDDGDAVTVP
FGTSLEEVDRRIILGTLAQCGGVKTHAAEVLDISLKTIYNRLAQLEAEGDDKTKR

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=39.4678492239468, Blast_Score=321, Evalue=8e-89,
Organism=Escherichia coli, GI1790437, Length=454, Percent_Identity=39.4273127753304, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=35.181236673774, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1788905, Length=453, Percent_Identity=34.878587196468, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1789087, Length=341, Percent_Identity=42.2287390029325, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI87082117, Length=247, Percent_Identity=47.3684210526316, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=39.4409937888199, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1786524, Length=343, Percent_Identity=39.9416909620991, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=40.9937888198758, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87081872, Length=261, Percent_Identity=42.911877394636, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1787583, Length=400, Percent_Identity=33.5, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87081858, Length=317, Percent_Identity=32.1766561514196, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789828, Length=361, Percent_Identity=30.4709141274238, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786838, Length=114, Percent_Identity=35.0877192982456, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49767; Mature: 49635

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYILIVEDDADTRDMLCALAHTQQLACDAAATLEEARALIATHTPDLVLCDLVLPDGNG
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
MDLFDELPKGAHVEMVLTTGHASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTGV
CCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCC
LHEEIAALRSELQRLGRFGRMLGRSPVMQTMYDAIGRVAGTEASVLLMGESGTGKELAAQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHH
TIHDLSLRRKGPFLAVNCGAIAANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFLD
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEECCCCEEEHH
EITEMPVESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNLDPEAAMADGKLRPDLYH
HHHCCCHHHHHHHHHHHHCCCCEECCCCCEECEEEEEEEECCCCHHHHHCCCCCCCCHHH
RINVFPITLPPLRARGDDIPMLAEAFLRQLGEDSGRKMRFSASALAALAEYDWPGNVREL
EEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCHHHH
RNFVQRACIFNDGEVIDTLPPPIMDEVASEPGDDGDAVTVPFGTSLEEVDRRIILGTLAQ
HHHHHHHHCCCCCCEECCCCCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
CGGVKTHAAEVLDISLKTIYNRLAQLEAEGDDKTKR
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PYILIVEDDADTRDMLCALAHTQQLACDAAATLEEARALIATHTPDLVLCDLVLPDGNG
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
MDLFDELPKGAHVEMVLTTGHASLETAIDALRRGATDYLVKPLNMQRLNSIFARVPRTGV
CCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCC
LHEEIAALRSELQRLGRFGRMLGRSPVMQTMYDAIGRVAGTEASVLLMGESGTGKELAAQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHH
TIHDLSLRRKGPFLAVNCGAIAANLVESEMFGHDRGSFTGADRQHKGFFERADGGTLFLD
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEECCCCEEEHH
EITEMPVESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNLDPEAAMADGKLRPDLYH
HHHCCCHHHHHHHHHHHHCCCCEECCCCCEECEEEEEEEECCCCHHHHHCCCCCCCCHHH
RINVFPITLPPLRARGDDIPMLAEAFLRQLGEDSGRKMRFSASALAALAEYDWPGNVREL
EEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCHHHH
RNFVQRACIFNDGEVIDTLPPPIMDEVASEPGDDGDAVTVPFGTSLEEVDRRIILGTLAQ
HHHHHHHHCCCCCCEECCCCCHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
CGGVKTHAAEVLDISLKTIYNRLAQLEAEGDDKTKR
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]