Click here to switch to the map view.

The map label for this gene is ribA [H]

Identifier: 126446144

GI number: 126446144

Start: 1174078

End: 1174665

Strand: Direct

Name: ribA [H]

Synonym: BMA10247_A1205

Alternate gene names: 126446144

Gene position: 1174078-1174665 (Clockwise)

Preceding gene: 126446480

Following gene: 126447546

Centisome position: 49.9

GC content: 66.5

Gene sequence:

>588_bases
GTGCCCATTCGTCCGCGCACCGCGCAACAGCGGTTCGACGCCGAAATGGTCACGTTCCAGGGCTTGTGCGACAGCGCCGA
GCATCTCGCGCTCGTTTTCGGGCCGCTCGCCGACGCGCCGCTCGTGCGCGTGCATTCCGAGTGCCTGACGGGCGACGTGT
TCGGCTCCGCGCGCTGCGATTGCGGCGAGCAGCTCGACGAGTCGGTCGCGATGTTCGGCCGTGAAGGCGGCATCCTGCTC
TATCTGCGCCAGGAGGGGCGCGGCATCGGGCTGTACAACAAGCTCGACGCGTACCGCCTGCAGATCTCGCAGGGCCTCGA
CACGTTCGCGGCGAACCGCGCGCTGAATTTCCCCGACGACCTGCGCGATTTCCGCGTCGCCGCGCAAATGCTGCAGGCGC
TCGGCGTCACCGAGATCTCGCTCGTCACCAACAACCCGGACAAGGTCTCGCAGATCGAGAAGCACGGCATCCGGATCCGG
CGCGTGCTGCAGACGGGCGTGTTCGTCAACACCACGAACCACGGCTACCTGCGCGCGAAGATCGATCACCACCGCCACGC
CATCAACCTCAGCCAGGAACTGCAATGA

Upstream 100 bases:

>100_bases
TTCGCGATGCGTATCTCAATGTTGAATAACCTTGAGGCACAGCATGAACGATGGTCGAATTTCCCCAACGATGAGCGCGT
CCGTCCGTACGCGCGTCAAT

Downstream 100 bases:

>100_bases
TCACTCACCGCGCACCGATCAGCGGGATTGCCGCGCACCGCGACCAGTACGTCCTGACGGCCGGTTACGACAACCAGGTC
ATCCTGTGGGACGCGAAGAC

Product: GTP cyclohydrolase II

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPIRPRTAQQRFDAEMVTFQGLCDSAEHLALVFGPLADAPLVRVHSECLTGDVFGSARCDCGEQLDESVAMFGREGGILL
YLRQEGRGIGLYNKLDAYRLQISQGLDTFAANRALNFPDDLRDFRVAAQMLQALGVTEISLVTNNPDKVSQIEKHGIRIR
RVLQTGVFVNTTNHGYLRAKIDHHRHAINLSQELQ

Sequences:

>Translated_195_residues
MPIRPRTAQQRFDAEMVTFQGLCDSAEHLALVFGPLADAPLVRVHSECLTGDVFGSARCDCGEQLDESVAMFGREGGILL
YLRQEGRGIGLYNKLDAYRLQISQGLDTFAANRALNFPDDLRDFRVAAQMLQALGVTEISLVTNNPDKVSQIEKHGIRIR
RVLQTGVFVNTTNHGYLRAKIDHHRHAINLSQELQ
>Mature_194_residues
PIRPRTAQQRFDAEMVTFQGLCDSAEHLALVFGPLADAPLVRVHSECLTGDVFGSARCDCGEQLDESVAMFGREGGILLY
LRQEGRGIGLYNKLDAYRLQISQGLDTFAANRALNFPDDLRDFRVAAQMLQALGVTEISLVTNNPDKVSQIEKHGIRIRR
VLQTGVFVNTTNHGYLRAKIDHHRHAINLSQELQ

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=180, Percent_Identity=47.7777777777778, Blast_Score=146, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6319438, Length=169, Percent_Identity=42.0118343195266, Blast_Score=114, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 21760; Mature: 21629

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRPRTAQQRFDAEMVTFQGLCDSAEHLALVFGPLADAPLVRVHSECLTGDVFGSARCD
CCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCC
CGEQLDESVAMFGREGGILLYLRQEGRGIGLYNKLDAYRLQISQGLDTFAANRALNFPDD
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCHH
LRDFRVAAQMLQALGVTEISLVTNNPDKVSQIEKHGIRIRRVLQTGVFVNTTNHGYLRAK
HHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEE
IDHHRHAINLSQELQ
ECCCHHEECHHHHCC
>Mature Secondary Structure 
PIRPRTAQQRFDAEMVTFQGLCDSAEHLALVFGPLADAPLVRVHSECLTGDVFGSARCD
CCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCC
CGEQLDESVAMFGREGGILLYLRQEGRGIGLYNKLDAYRLQISQGLDTFAANRALNFPDD
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCHH
LRDFRVAAQMLQALGVTEISLVTNNPDKVSQIEKHGIRIRRVLQTGVFVNTTNHGYLRAK
HHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEE
IDHHRHAINLSQELQ
ECCCHHEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]