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The map label for this gene is bpeE [H]

Identifier: 126445936

GI number: 126445936

Start: 761719

End: 762939

Strand: Direct

Name: bpeE [H]

Synonym: BMA10247_A0827

Alternate gene names: 126445936

Gene position: 761719-762939 (Clockwise)

Preceding gene: 126447855

Following gene: 126447052

Centisome position: 32.38

GC content: 71.25

Gene sequence:

>1221_bases
TTGCGTACTTCCCGTTCGCGGATCGCGGCCGCGGCGTTCGCGGTCGTCTTCATCGCGGGCCTCGGCACGTTCGGCGCGAT
CCGCGTGAATGCCGGCGCGCCGGAGAAATCGGCGGCGCCGCTGCCGGAGGTCGACGTCGCGACCGTGCTGTCGAAGACGA
TCACCGATTGGCAGTCCTACTCGGGCCGCCTCGAGGCGGTCGAGAAGGTCGACGTGCGCCCGCTCGTGTCCGGCACGATC
GTGTCGGTGAATTTCAAGGACGGCGCGCTCGTGAAGAAGGGCGACGTGCTGTTCGTGATCGATCCGCGCCCGTATCAGGC
CGAGGTCGATCGCGCGGCCGCGCAGCTCGCCGGCGCGCAGGCCCGCAATGGCTACGCACAGAGCGACTGGCAGCGCGCGC
AGCGGCTGATCGGCGACAACGCGATCGCCAAGCGCGATTACGACGAGAAGCAGAACGCCGCGCGCGAGGCCTCGGCGAAC
CTGAAGGCGGCCGAGGCCGCGCTCGAGACGGCGCGCATCAACCTCGGCTACACGCGGATCACCGCGCCCGTGTCGGGCCG
CGTGTCGCGCGCGGAGATCACGCTCGGCAACGTCGTGTCGGCGGGCGCGTCGGCCGCACCGCTCACGACGCTCGTGTCGG
TGTCGCCGATCTACGCGTCGTTCGACGCGGACGAGCAGACCTACCTGCAATACATCGGCGGCGCGAAGGACGGCCGCAAG
GTGCCCGTCGAGCTCGGCCTCGCGAACGAGAGCGGCTACTCGCGGCAGGGCGTGATCGATTCGGTCGACAACCGGCTCGA
TACGTCGTCGGGCACGATCCGCGTGCGCGCGCGCTTCGACAACGCGGACGGCGCGCTCGTGCCCGGCCTCTACGCGCGCG
TGAAGGTGGGCGGCAGCGCGCCGCATCCGGCGCTGCTCATCGACGACGCGGCGATCAACACCGATCAGGACAAGAAGTTC
GTGTTCGTCGTCGATCAGCAGGGCCGCGTGTCGTATCGCGAGGTGCAGCTCGGCGCGCAGCACGGCAACCAGCGCGTGAT
CGTGGGCGGCCTGGCTGCGAGCGAGCGCATCGTCGTGAACGGCACGCAGCGCGTGCGGCCGGGCGAGCAGGTGAAGCCGC
ATCTCGTGCCGATGACGGGCGGCGACGACGCTGCCGCCGCGACGCCCGTCGCGGGCGGCGTGCAGCGTCCGCGGGCCGCG
CAGGGCAACGCGCGCGCGTGA

Upstream 100 bases:

>100_bases
CGTTTCTTCCAGTTCCGCTTCAGCGCGGGTGCACCGGGCTGACGCCGTTTTCATCCGAATTCAGAACAACCGACAACCTG
GGGGTTTTTTCATGGCTATC

Downstream 100 bases:

>100_bases
CGCCCGAACGCTCCCGACGAGCGTTCGCCGCGCCAGCGCGCCCAATCAGACAGAGCCTTTCATGAACATATCGAAATTCT
TCATCGATCGACCGATCTTC

Product: multidrug efflux pump BpeE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDWQSYSGRLEAVEKVDVRPLVSGTI
VSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAGAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREASAN
LKAAEAALETARINLGYTRITAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKDGRK
VPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVGGSAPHPALLIDDAAINTDQDKKF
VFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERIVVNGTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRPRAA
QGNARA

Sequences:

>Translated_406_residues
MRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDWQSYSGRLEAVEKVDVRPLVSGTI
VSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAGAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREASAN
LKAAEAALETARINLGYTRITAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKDGRK
VPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVGGSAPHPALLIDDAAINTDQDKKF
VFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERIVVNGTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRPRAA
QGNARA
>Mature_406_residues
MRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDWQSYSGRLEAVEKVDVRPLVSGTI
VSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAGAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREASAN
LKAAEAALETARINLGYTRITAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKDGRK
VPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVGGSAPHPALLIDDAAINTDQDKKF
VFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERIVVNGTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRPRAA
QGNARA

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=341, Percent_Identity=33.1378299120235, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87082036, Length=335, Percent_Identity=30.7462686567164, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1786668, Length=381, Percent_Identity=32.8083989501312, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789665, Length=351, Percent_Identity=32.1937321937322, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87081796, Length=375, Percent_Identity=27.7333333333333, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081951, Length=230, Percent_Identity=31.7391304347826, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789637, Length=141, Percent_Identity=34.0425531914894, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790519, Length=249, Percent_Identity=26.9076305220884, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42738; Mature: 42738

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDWQSY
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
SGRLEAVEKVDVRPLVSGTIVSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAGAQ
CCHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHHCCH
ARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREASANLKAAEAALETARINLGYTRI
HCCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHEEECCEEEE
TAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKDGRK
ECCCCCCCEEEEEEECHHHHCCCCCCCHHHEEEECCEEEECCCCHHHHHHHHCCCCCCCC
VPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVGGSA
CEEEEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCC
PHPALLIDDAAINTDQDKKFVFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERIVVN
CCCEEEEECCCCCCCCCCEEEEEECCCCCCEEEEEEEHHCCCCCEEEEEECCCCCEEEEE
GTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRPRAAQGNARA
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDWQSY
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
SGRLEAVEKVDVRPLVSGTIVSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAGAQ
CCHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHHCCH
ARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREASANLKAAEAALETARINLGYTRI
HCCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHEEECCEEEE
TAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKDGRK
ECCCCCCCEEEEEEECHHHHCCCCCCCHHHEEEECCEEEECCCCHHHHHHHHCCCCCCCC
VPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVGGSA
CEEEEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECCCC
PHPALLIDDAAINTDQDKKFVFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERIVVN
CCCEEEEECCCCCCCCCCEEEEEECCCCCCEEEEEEEHHCCCCCEEEEEECCCCCEEEEE
GTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRPRAAQGNARA
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]