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The map label for this gene is dasR [H]

Identifier: 126445713

GI number: 126445713

Start: 1356577

End: 1357302

Strand: Direct

Name: dasR [H]

Synonym: BMA10247_A1390

Alternate gene names: 126445713

Gene position: 1356577-1357302 (Clockwise)

Preceding gene: 126446556

Following gene: 126446309

Centisome position: 57.66

GC content: 70.94

Gene sequence:

>726_bases
ATGCACGCCACCGACGACCGTCTCCCCCGCTACCAGCGCCTGCGCGACGAACTGGCCGCGCTGATCGCGGCCCGGCACTG
GCGGCCGGGCGAAGCGATCCCGACCGAGCAGGCGCTCGCGAAGCGCTATGACGTCGCGATCGGCACGGTGCGCAAGGCGG
TCGATCTGCTCGTCGCCGACGGCATGCTCGAACGCTTCCAGGGGCGCGGCACGTTCGTGCGGCGCGCGAGCTTCGACAGC
TCGCTGTTCCGTTTCTTCCGCTTCCAGGGCAGGCACGGCGAGCGCCGGATACCGGAGAGCCGGATCCTGCGCCGCGAGGT
CGTCGAAGCGCCGTCCGCGGTGGCGGCCGCGCTGCAGATTCCGGCCCGCGCGTCGGTGATCGAGATGACGCGGGTGCGCC
TGATCGACGGCGCGCCGATGCTCGCCGAGGAAATCTGGCTGCCCTACGACCGCTTCGCCGCATTCGCGCGGCTCGAGCTC
GCTTCGATCGGCGATCTGCTGTATCCGGTCTACGAAGCGCATTGCAACCAGATCGTCGCCTCGGCCACCGAGACGCTGAC
CGTCGAGGCGATCGGCCCCGTGCACGCGCGGCTGCTGCGCATCGAGCCGGGCACGCCCGCCGTCGTGATCGAGCGGCTCG
CGTACGGCTACGACCGCCGGCCGCTCGAATGGCGGCGCTCGCGCGGCCCCGCGAGCGAATTCATCTATCAGGCGGAAATC
CGCTAG

Upstream 100 bases:

>100_bases
TTACCAGTGCAGCCTGCCTGAATTGGGAAAGCACCATCGGGTTTGTCCCGATTCGCTCCGAACCAAGTCATGCAAACATA
TAGATGAATTTGGAGAAACC

Downstream 100 bases:

>100_bases
CGGCCGGCTCGCGCGACAGCGGAGCTCGCGCACGGGCCGCGCGCTCGCGCGAGCAACGCATGGAGCAGCGTGCGGCGCGC
ATGGCGAGCAGCGCCCGACA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MHATDDRLPRYQRLRDELAALIAARHWRPGEAIPTEQALAKRYDVAIGTVRKAVDLLVADGMLERFQGRGTFVRRASFDS
SLFRFFRFQGRHGERRIPESRILRREVVEAPSAVAAALQIPARASVIEMTRVRLIDGAPMLAEEIWLPYDRFAAFARLEL
ASIGDLLYPVYEAHCNQIVASATETLTVEAIGPVHARLLRIEPGTPAVVIERLAYGYDRRPLEWRRSRGPASEFIYQAEI
R

Sequences:

>Translated_241_residues
MHATDDRLPRYQRLRDELAALIAARHWRPGEAIPTEQALAKRYDVAIGTVRKAVDLLVADGMLERFQGRGTFVRRASFDS
SLFRFFRFQGRHGERRIPESRILRREVVEAPSAVAAALQIPARASVIEMTRVRLIDGAPMLAEEIWLPYDRFAAFARLEL
ASIGDLLYPVYEAHCNQIVASATETLTVEAIGPVHARLLRIEPGTPAVVIERLAYGYDRRPLEWRRSRGPASEFIYQAEI
R
>Mature_241_residues
MHATDDRLPRYQRLRDELAALIAARHWRPGEAIPTEQALAKRYDVAIGTVRKAVDLLVADGMLERFQGRGTFVRRASFDS
SLFRFFRFQGRHGERRIPESRILRREVVEAPSAVAAALQIPARASVIEMTRVRLIDGAPMLAEEIWLPYDRFAAFARLEL
ASIGDLLYPVYEAHCNQIVASATETLTVEAIGPVHARLLRIEPGTPAVVIERLAYGYDRRPLEWRRSRGPASEFIYQAEI
R

Specific function: Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N- acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=214, Percent_Identity=29.9065420560748, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1786950, Length=231, Percent_Identity=28.1385281385281, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790118, Length=234, Percent_Identity=26.4957264957265, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1790540, Length=165, Percent_Identity=31.5151515151515, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788418, Length=243, Percent_Identity=24.2798353909465, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27392; Mature: 27392

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHATDDRLPRYQRLRDELAALIAARHWRPGEAIPTEQALAKRYDVAIGTVRKAVDLLVAD
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GMLERFQGRGTFVRRASFDSSLFRFFRFQGRHGERRIPESRILRREVVEAPSAVAAALQI
HHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHC
PARASVIEMTRVRLIDGAPMLAEEIWLPYDRFAAFARLELASIGDLLYPVYEAHCNQIVA
CCHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATETLTVEAIGPVHARLLRIEPGTPAVVIERLAYGYDRRPLEWRRSRGPASEFIYQAEI
HHHHEEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHCCCCHHHHEEEECC
R
C
>Mature Secondary Structure
MHATDDRLPRYQRLRDELAALIAARHWRPGEAIPTEQALAKRYDVAIGTVRKAVDLLVAD
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GMLERFQGRGTFVRRASFDSSLFRFFRFQGRHGERRIPESRILRREVVEAPSAVAAALQI
HHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHC
PARASVIEMTRVRLIDGAPMLAEEIWLPYDRFAAFARLELASIGDLLYPVYEAHCNQIVA
CCHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATETLTVEAIGPVHARLLRIEPGTPAVVIERLAYGYDRRPLEWRRSRGPASEFIYQAEI
HHHHEEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHCCCCHHHHEEEECC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]