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The map label for this gene is alr [H]

Identifier: 126444859

GI number: 126444859

Start: 1012172

End: 1013296

Strand: Reverse

Name: alr [H]

Synonym: BURPS668_A1047

Alternate gene names: 126444859

Gene position: 1013296-1012172 (Counterclockwise)

Preceding gene: 126443339

Following gene: 126442867

Centisome position: 32.4

GC content: 71.91

Gene sequence:

>1125_bases
ATGCCTCGCCCCATCGTCGCCCGCATTCATCCCGACGCCGTCGCGCACAATCTTGCAATCGTCCGGCAAAAGGCGCCGAA
CGCGCGTATCTGGTCGGTCGTCAAGGCGAACGCGTACGGCCACGGCATCGAGCATGTCTATCCGGCGCTCGCCGGCGCGG
ACGGCATCGCGCTGCTCGACCTCGACGAAGCGGTGCGCGTGCGCGAGCTCGGCTGGACGAAGCCCGTGCTGCTGCTCGAA
GGCATCTTCGAGGCGGCCGATGTCGAGATCGCGGATCGCCATCGGCTGACGGTCGCCGTGCACGGCGACGAGCAGTTGAA
GCTGCTCACCGCCGCGAAGACGACGCGCCCGATCGACATCCAACTGAAGATGAACTCCGGGATGAACCGGCTCGGCTACC
GGCCGCATGCGTTGCGCGCCGCGTGGGAACGCGCGGCCGCCGCGCCGTCGATCGGCCGCATCGCGCTGATGATGCATTTC
GCGAACGCCGACGAAGGCGAGATCGACTGGCAGATGAGCGTGTTCGACGCGGCGACGCAGGGCCTGCCCGGCGAGCGCAC
GCTGTCGAACTCGGCCGCCGTGCTGTGGCATCCGCGCGCGCACCGCGACTGGGTGCGCCCCGGCACGATCCTGTACGGCG
CGTCGCCCACGGGCGCGAGCCGCCACGTCGCCGACGTGCCGCTGCGGGCCGCGATGACGGTCACGAGCCGGATCATCGGC
GTGCAAACGCTGACGCCGGGCGAGACGGTCGGCTACGGGCGCTGCTTCGCGGCCGAGCGCGAGATGCGCATCGGCGTCGT
CGCCTGCGGCTACGCGGACGGCTATCCGCGCCACGCGCCCACCGGCACGCCGATCGCGGTCGACGGCGTGCGCACGCAAG
TGGTCGGGCGCGTGTCGATGGACATGCTGACCGTCGACCTCACGCCGTGTCCGAACGCGGGCGTCGGCTCGGCCGTCGAG
CTGTGGGGCGAGCAGGTGCGCGTCGACGACGTCGCCGAAGCCGCGGGCACGATCGGCTACGAGCTGATGTGCGCGCTCGC
GCGGCGCGTGCCGGTCACCGTCGATCCGTCGCCCGCCGCGGCCGCGCTCGCCCGGCCGGTGCGCACCGGAAGCTACGGGC
GCTGA

Upstream 100 bases:

>100_bases
GCGTCTCGCACGGCGAATATCCACCAAACGAGCGCCATCGATTCACCCGCGCGGCGCGGCGCATACGAGCGCGCGCCGCC
TTGACTTCTCAGAGAGATTC

Downstream 100 bases:

>100_bases
ACGATGCGCGCGCCGACGCCGGCGAAAGCCGGCGCGCGGCGGGAGCCGGCCCGGCGCGCCGCGCGCGCGCCGACGGGCTT
CGCGTTCGAGCGCGCGCGCA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MPRPIVARIHPDAVAHNLAIVRQKAPNARIWSVVKANAYGHGIEHVYPALAGADGIALLDLDEAVRVRELGWTKPVLLLE
GIFEAADVEIADRHRLTVAVHGDEQLKLLTAAKTTRPIDIQLKMNSGMNRLGYRPHALRAAWERAAAAPSIGRIALMMHF
ANADEGEIDWQMSVFDAATQGLPGERTLSNSAAVLWHPRAHRDWVRPGTILYGASPTGASRHVADVPLRAAMTVTSRIIG
VQTLTPGETVGYGRCFAAEREMRIGVVACGYADGYPRHAPTGTPIAVDGVRTQVVGRVSMDMLTVDLTPCPNAGVGSAVE
LWGEQVRVDDVAEAAGTIGYELMCALARRVPVTVDPSPAAAALARPVRTGSYGR

Sequences:

>Translated_374_residues
MPRPIVARIHPDAVAHNLAIVRQKAPNARIWSVVKANAYGHGIEHVYPALAGADGIALLDLDEAVRVRELGWTKPVLLLE
GIFEAADVEIADRHRLTVAVHGDEQLKLLTAAKTTRPIDIQLKMNSGMNRLGYRPHALRAAWERAAAAPSIGRIALMMHF
ANADEGEIDWQMSVFDAATQGLPGERTLSNSAAVLWHPRAHRDWVRPGTILYGASPTGASRHVADVPLRAAMTVTSRIIG
VQTLTPGETVGYGRCFAAEREMRIGVVACGYADGYPRHAPTGTPIAVDGVRTQVVGRVSMDMLTVDLTPCPNAGVGSAVE
LWGEQVRVDDVAEAAGTIGYELMCALARRVPVTVDPSPAAAALARPVRTGSYGR
>Mature_373_residues
PRPIVARIHPDAVAHNLAIVRQKAPNARIWSVVKANAYGHGIEHVYPALAGADGIALLDLDEAVRVRELGWTKPVLLLEG
IFEAADVEIADRHRLTVAVHGDEQLKLLTAAKTTRPIDIQLKMNSGMNRLGYRPHALRAAWERAAAAPSIGRIALMMHFA
NADEGEIDWQMSVFDAATQGLPGERTLSNSAAVLWHPRAHRDWVRPGTILYGASPTGASRHVADVPLRAAMTVTSRIIGV
QTLTPGETVGYGRCFAAEREMRIGVVACGYADGYPRHAPTGTPIAVDGVRTQVVGRVSMDMLTVDLTPCPNAGVGSAVEL
WGEQVRVDDVAEAAGTIGYELMCALARRVPVTVDPSPAAAALARPVRTGSYGR

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=59.7733711048159, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1790487, Length=346, Percent_Identity=42.485549132948, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40088; Mature: 39957

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPIVARIHPDAVAHNLAIVRQKAPNARIWSVVKANAYGHGIEHVYPALAGADGIALLD
CCCCEEEEECCHHHHHCEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCEEEEE
LDEAVRVRELGWTKPVLLLEGIFEAADVEIADRHRLTVAVHGDEQLKLLTAAKTTRPIDI
CHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCEEEEEEEECCCCEEEEEECCCCCCEEE
QLKMNSGMNRLGYRPHALRAAWERAAAAPSIGRIALMMHFANADEGEIDWQMSVFDAATQ
EEEECCCCHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEEHHHHHC
GLPGERTLSNSAAVLWHPRAHRDWVRPGTILYGASPTGASRHVADVPLRAAMTVTSRIIG
CCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEE
VQTLTPGETVGYGRCFAAEREMRIGVVACGYADGYPRHAPTGTPIAVDGVRTQVVGRVSM
EEEECCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEECCHHEEHHHEEEE
DMLTVDLTPCPNAGVGSAVELWGEQVRVDDVAEAAGTIGYELMCALARRVPVTVDPSPAA
EEEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHH
AALARPVRTGSYGR
HHHHCCCCCCCCCC
>Mature Secondary Structure 
PRPIVARIHPDAVAHNLAIVRQKAPNARIWSVVKANAYGHGIEHVYPALAGADGIALLD
CCCEEEEECCHHHHHCEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCEEEEE
LDEAVRVRELGWTKPVLLLEGIFEAADVEIADRHRLTVAVHGDEQLKLLTAAKTTRPIDI
CHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCEEEEEEEECCCCEEEEEECCCCCCEEE
QLKMNSGMNRLGYRPHALRAAWERAAAAPSIGRIALMMHFANADEGEIDWQMSVFDAATQ
EEEECCCCHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEEHHHHHC
GLPGERTLSNSAAVLWHPRAHRDWVRPGTILYGASPTGASRHVADVPLRAAMTVTSRIIG
CCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEE
VQTLTPGETVGYGRCFAAEREMRIGVVACGYADGYPRHAPTGTPIAVDGVRTQVVGRVSM
EEEECCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEECCHHEEHHHEEEE
DMLTVDLTPCPNAGVGSAVELWGEQVRVDDVAEAAGTIGYELMCALARRVPVTVDPSPAA
EEEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHH
AALARPVRTGSYGR
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA