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The map label for this gene is xerD [H]

Identifier: 126209006

GI number: 126209006

Start: 1756562

End: 1757455

Strand: Reverse

Name: xerD [H]

Synonym: APL_1542

Alternate gene names: 126209006

Gene position: 1757455-1756562 (Counterclockwise)

Preceding gene: 126209007

Following gene: 126209004

Centisome position: 77.27

GC content: 40.16

Gene sequence:

>894_bases
ATGAAAAATTTAGATCCTATTATCGAACAGTTTTTAGATACGTTATGGCAAGAACACGGATTATCTGAAAATACGTCGGC
TGCATACCGTTTAGACTTGGAATCCTTCTCCGAATGGTTACCTACGCCTAAAGCATTTCTTACTTTAGATCATTTTGACC
TGCAAGCATTCTTGGGAGGAAGATTGGAACTGGGCTATAAGGCAACCAGTTCAGCTAGAATGCTTAGTTGCTTGCGTAAA
TTTTTCCGTTTTTTATATACGGAAAATTATCGTCAAGACGATCCTACTCTCACTTTAACTTCTCCGCGTAAGCCGGCGCA
TTTGCCTAAATCTTTAAGTGAAGAGCAAGTAATGGATTTATTGGATAGTCCGAATACGTTAGATCCTATCGAATTACGCG
ATAAAGCAATGTTAGAATTACTGTATGCAACGGGGTTACGTGTTAGCGAATTGGTATCGCTTAGCATAGATAATCTAAGC
TTACGCCAAGGTGTGGTACGTGTTGTGGGGAAAGGCGATAAAGAGAGATTAGTACCGATAGGTGAAGAAGCCGGTTATTG
GATTCAAGAATTCTTTCGGTATGGGCGTGCAATATTATTAAATAATCTACAATCAGATGTTGTTTTTCCAAGTCGCCGAG
GACAGCAAATGACTCGCCAAACATTTTGGCATAGAATAAAACATTACGCCGTTTTGGCCGGTATTGATAGTGAGAAACTA
TCTCCACATGTATTGCGTCATGCTTTTGCCACGCATTTGGTTAATCACGGTGCCGATTTAAGGGTAGTTCAAATGTTATT
AGGGCATAGTGATCTCTCTACGACGCAAATTTATACGCATGTCGCGAAAGCACGTTTAAAATCACTACATCAACAATTTC
ATCCGCGGGGATAA

Upstream 100 bases:

>100_bases
GATTAGTTTATGCTAGTCGGCTTTTTGCACATTTGTACTTTTCTCTAAAGTGAAGTTATTCTGTTAGAATAATAGAATAT
CTAGGAATAAAAGTAGCTTC

Downstream 100 bases:

>100_bases
TATGCAGAAATCATCATCTAAATTTAATTGGGCATTAGCATTACTTTGCTTACCTTGAGCATTATGGCCGCTTGCGCTAC
TGGTTTCACCGAAATTCTCC

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKNLDPIIEQFLDTLWQEHGLSENTSAAYRLDLESFSEWLPTPKAFLTLDHFDLQAFLGGRLELGYKATSSARMLSCLRK
FFRFLYTENYRQDDPTLTLTSPRKPAHLPKSLSEEQVMDLLDSPNTLDPIELRDKAMLELLYATGLRVSELVSLSIDNLS
LRQGVVRVVGKGDKERLVPIGEEAGYWIQEFFRYGRAILLNNLQSDVVFPSRRGQQMTRQTFWHRIKHYAVLAGIDSEKL
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKARLKSLHQQFHPRG

Sequences:

>Translated_297_residues
MKNLDPIIEQFLDTLWQEHGLSENTSAAYRLDLESFSEWLPTPKAFLTLDHFDLQAFLGGRLELGYKATSSARMLSCLRK
FFRFLYTENYRQDDPTLTLTSPRKPAHLPKSLSEEQVMDLLDSPNTLDPIELRDKAMLELLYATGLRVSELVSLSIDNLS
LRQGVVRVVGKGDKERLVPIGEEAGYWIQEFFRYGRAILLNNLQSDVVFPSRRGQQMTRQTFWHRIKHYAVLAGIDSEKL
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKARLKSLHQQFHPRG
>Mature_297_residues
MKNLDPIIEQFLDTLWQEHGLSENTSAAYRLDLESFSEWLPTPKAFLTLDHFDLQAFLGGRLELGYKATSSARMLSCLRK
FFRFLYTENYRQDDPTLTLTSPRKPAHLPKSLSEEQVMDLLDSPNTLDPIELRDKAMLELLYATGLRVSELVSLSIDNLS
LRQGVVRVVGKGDKERLVPIGEEAGYWIQEFFRYGRAILLNNLQSDVVFPSRRGQQMTRQTFWHRIKHYAVLAGIDSEKL
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKARLKSLHQQFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=68.7285223367698, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1790244, Length=299, Percent_Identity=36.7892976588629, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1790768, Length=162, Percent_Identity=32.7160493827161, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790767, Length=180, Percent_Identity=29.4444444444444, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34066; Mature: 34066

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLDPIIEQFLDTLWQEHGLSENTSAAYRLDLESFSEWLPTPKAFLTLDHFDLQAFLGG
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHCCCCHHEEEECHHHHHHHHCC
RLELGYKATSSARMLSCLRKFFRFLYTENYRQDDPTLTLTSPRKPAHLPKSLSEEQVMDL
CEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
LDSPNTLDPIELRDKAMLELLYATGLRVSELVSLSIDNLSLRQGVVRVVGKGDKERLVPI
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
GEEAGYWIQEFFRYGRAILLNNLQSDVVFPSRRGQQMTRQTFWHRIKHYAVLAGIDSEKL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCHHC
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKARLKSLHQQFHPRG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNLDPIIEQFLDTLWQEHGLSENTSAAYRLDLESFSEWLPTPKAFLTLDHFDLQAFLGG
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHCCCCHHEEEECHHHHHHHHCC
RLELGYKATSSARMLSCLRKFFRFLYTENYRQDDPTLTLTSPRKPAHLPKSLSEEQVMDL
CEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
LDSPNTLDPIELRDKAMLELLYATGLRVSELVSLSIDNLSLRQGVVRVVGKGDKERLVPI
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
GEEAGYWIQEFFRYGRAILLNNLQSDVVFPSRRGQQMTRQTFWHRIKHYAVLAGIDSEKL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCHHC
SPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKARLKSLHQQFHPRG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA