| Definition | Actinobacillus pleuropneumoniae serovar 5b str. L20 chromosome, complete genome. |
|---|---|
| Accession | NC_009053 |
| Length | 2,274,482 |
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The map label for this gene is clpP2 [H]
Identifier: 126207994
GI number: 126207994
Start: 579501
End: 581525
Strand: Direct
Name: clpP2 [H]
Synonym: APL_0510
Alternate gene names: 126207994
Gene position: 579501-581525 (Clockwise)
Preceding gene: 126207993
Following gene: 126207995
Centisome position: 25.48
GC content: 45.43
Gene sequence:
>2025_bases ATGAGAAAAAAACAAATGGTTCTAGCCCCGATGGCGAAGGCAGTAGCAGTAACCAAGACGAATAATCAGTCTTGGTTTAC GATTAAAGCTGCGGCCAACGACACCGCAGAGATTAGCATTTATGATGAAATCGGTTTTTGGGGTGTTACAGCCCAACAGT TTGCCAACGATTTAAAAGCCCTTGGAAACAATCTCAAACAGATCAATCTGCATATCCACTCGCCCGGAGGCGATGTGTTT GATGGTATTGCCATCTACAATTTGCTGAAAAATCACCCTGCTAACAAGACCGTCTATATCGACGGTCTTGCTGCATCTAT GGCTTCAGTTATTGCAATGGCTGGTAACGAAATCATTATGCCCGAAAACGCAATGATGATGATCCACAAGCCGTGGGGAA TCCAAGGCGGTGATGCTGATGATATGCGGAAATATGCGGATTTGCTTGATAAGGTCGAAAGTACCCTGATTATGGCCTAT GTCGCTAAAACAGAAAAATCCGAAGAAGAATTAGCAGAAATGCTGAAAGAAGAAACTTGGCTCACAGGCAAAGAGTGCGT GGAGCAAGGTTTCGCCGATAAGTTAGCCGAACCCCTTGTGGCGATGGCTTGTATCCAATCCAAAAAATTAGAGGACTACA CAAAAATGCCTGACAAAATCAAAAATATGCTATTCGCACCACAAGGCAACGCAGGTGCAAATCCAAAACCTGAACAACCT CAAACACCACCACAAGCGGGTGAAAATCCGCAAAATGTGGCAAAACCTGATGCAATGGTGGCATTAGCCCAACGCAATGC AACGATTAAAGCGACCTTTGCCGCTTTCGGCACACAATTTGACGGCTTACTGGCAGAATGTTTAGCTGATGTGTCAATGA CCGCTGAGCAAGCCAAAGACAAGCTCCTTGCCAAACTGGGCGAAAACACCACCCCAAGCGTACCGCAAAACCACATTCAC GCAGGTAACGGTAACATCGTTGGCGACAGCGTGAAGCAGTCGTTAATGGCTCGTGCTGGTCAAGATACCGACAAAACCAA CGCAAGAGATAATACCTACAATGCAATGACCTTGCGTGAGTTGGCTCGTGCCTCATTGGTTGATCGTGGCGTGGGTATTG CGGGCTACACCCCAATGCAGATGGTCGGTCTTGCCTTTACGCACTCAAGTTCTGATTTCGGTCAAATCTTAATTGATGTA GCACATAAATCCTTGCTAAAAGGCTGGGAAGTATCAAACGAAAATTACGAACAATTTACCTCACGCGGTATTTTAACCGA CTTCCGTCCGGCTAAACGTGTTGGCTTAGGGGAATTTGGCTACTTACCAACCGTGGGTGAGGGTGAAGAATACACCTATG GTACACTCGGTGATGAAGGCGCATCTATCGCACTCGCTACCTACGGGCAATTATTTAGCATTACCCGTCAGGCGATCATC AATGATGATATGCACCTCTTGACCACCATTCCTCAAAAAATGGGGCAAGCGGCACGTGCAACCATCGCAAAATTGGTATT TGCCTTGATTACAGGTAATGCAACTGCTCAAGATGGCAAAAAATTGTTTGACGCAAGTCATAAAAACAGCCTCACAGGGG CAAAATTGGACGTTGAACATATCGATAAAGCGGTGCAATTGATGAATGGTTTTGTAAACAGCCGTGGTGAACCATTAGCG ATTGAGCCAGAATTTATGTTGCTCCCAACCTCGCTACATACCAAAGCGAAGCAGATCTTAGGCTCATCAAGTGTCGAAGG AGCAGACATCAACAGCGGTATCATTAACCCAATCCGTGATATTGTTAGCCCGATTAAATCGCCACGTTTACAGATTGCCG ATGCGAAATCGTGGTATCTCATCAACAAAGAAGCTATTGAAGTTTCTTATCTTGATGGTGTAGATAGCCCGTATATCGAA CAGCAACAAGGCTTCTCGGTAGATGGTGTTACCACAAAAGTTCGCATTGATGCCGGCGTAAATGTGATTGATTATCGTGG TATTGTGAAAGTCACAAACCAGTAA
Upstream 100 bases:
>100_bases CCAGCCGAAGTCAAACGGCAACGAATTGTCGAGATCAAAGAGAATGCTCGTGAGGGCTTGAAATTTGATACTGATTTAAC CAACACGCAAGGAATTAGTA
Downstream 100 bases:
>100_bases CTAGCAAATAACTTATAGACCGTACTTTAATCAATAAGGTACGGTTTTTTATTATCTGAAAAAGGAAAACCTTATGGCTA AAAACTATATTCAGGATGGT
Product: putative Clp-like protease
Products: NA
Alternate protein names: Endopeptidase Clp 2 [H]
Number of amino acids: Translated: 674; Mature: 674
Protein sequence:
>674_residues MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKALGNNLKQINLHIHSPGGDVF DGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIMPENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAY VAKTEKSEEELAEMLKEETWLTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKDKLLAKLGENTTPSVPQNHIH AGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRELARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDV AHKSLLKGWEVSNENYEQFTSRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEHIDKAVQLMNGFVNSRGEPLA IEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRDIVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIE QQQGFSVDGVTTKVRIDAGVNVIDYRGIVKVTNQ
Sequences:
>Translated_674_residues MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKALGNNLKQINLHIHSPGGDVF DGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIMPENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAY VAKTEKSEEELAEMLKEETWLTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKDKLLAKLGENTTPSVPQNHIH AGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRELARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDV AHKSLLKGWEVSNENYEQFTSRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEHIDKAVQLMNGFVNSRGEPLA IEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRDIVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIE QQQGFSVDGVTTKVRIDAGVNVIDYRGIVKVTNQ >Mature_674_residues MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKALGNNLKQINLHIHSPGGDVF DGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIMPENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAY VAKTEKSEEELAEMLKEETWLTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKDKLLAKLGENTTPSVPQNHIH AGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRELARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDV AHKSLLKGWEVSNENYEQFTSRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEHIDKAVQLMNGFVNSRGEPLA IEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRDIVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIE QQQGFSVDGVTTKVRIDAGVNVIDYRGIVKVTNQ
Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S14 family [H]
Homologues:
Organism=Caenorhabditis elegans, GI17538017, Length=133, Percent_Identity=29.3233082706767, Blast_Score=67, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001907 - InterPro: IPR018215 [H]
Pfam domain/function: PF00574 CLP_protease [H]
EC number: =3.4.21.92 [H]
Molecular weight: Translated: 73046; Mature: 73046
Theoretical pI: Translated: 5.42; Mature: 5.42
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKA CCCCHHHHHHHHHEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHH LGNNLKQINLHIHSPGGDVFDGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIM HCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCEEEC PENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAYVAKTEKSEEELAEMLKEETW CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC LTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEECCCCCCCCCCCCCCC QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKD CCCCCCCCCCHHCCCCHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHH KLLAKLGENTTPSVPQNHIHAGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRE HHHHHHCCCCCCCCCCCCEECCCCCEECHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH LARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDVAHKSLLKGWEVSNENYEQFT HHHHHHHHCCCCCCCCCHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH SRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII HCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHH NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEH CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEECHHH IDKAVQLMNGFVNSRGEPLAIEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRD HHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH IVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIEQQQGFSVDGVTTKVRIDAGV HHHHHCCCCEEEECCCEEEEEECCEEEEEEECCCCCCCCHHHCCCCCCCCEEEEEECCCC NVIDYRGIVKVTNQ CEEECCCEEEECCC >Mature Secondary Structure MRKKQMVLAPMAKAVAVTKTNNQSWFTIKAAANDTAEISIYDEIGFWGVTAQQFANDLKA CCCCHHHHHHHHHEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHH LGNNLKQINLHIHSPGGDVFDGIAIYNLLKNHPANKTVYIDGLAASMASVIAMAGNEIIM HCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCEEEC PENAMMMIHKPWGIQGGDADDMRKYADLLDKVESTLIMAYVAKTEKSEEELAEMLKEETW CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC LTGKECVEQGFADKLAEPLVAMACIQSKKLEDYTKMPDKIKNMLFAPQGNAGANPKPEQP CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEECCCCCCCCCCCCCCC QTPPQAGENPQNVAKPDAMVALAQRNATIKATFAAFGTQFDGLLAECLADVSMTAEQAKD CCCCCCCCCCHHCCCCHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHH KLLAKLGENTTPSVPQNHIHAGNGNIVGDSVKQSLMARAGQDTDKTNARDNTYNAMTLRE HHHHHHCCCCCCCCCCCCEECCCCCEECHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH LARASLVDRGVGIAGYTPMQMVGLAFTHSSSDFGQILIDVAHKSLLKGWEVSNENYEQFT HHHHHHHHCCCCCCCCCHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH SRGILTDFRPAKRVGLGEFGYLPTVGEGEEYTYGTLGDEGASIALATYGQLFSITRQAII HCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHH NDDMHLLTTIPQKMGQAARATIAKLVFALITGNATAQDGKKLFDASHKNSLTGAKLDVEH CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEECHHH IDKAVQLMNGFVNSRGEPLAIEPEFMLLPTSLHTKAKQILGSSSVEGADINSGIINPIRD HHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH IVSPIKSPRLQIADAKSWYLINKEAIEVSYLDGVDSPYIEQQQGFSVDGVTTKVRIDAGV HHHHHCCCCEEEECCCEEEEEECCEEEEEEECCCCCCCCHHHCCCCCCCCEEEEEECCCC NVIDYRGIVKVTNQ CEEECCCEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11214968 [H]