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The map label for this gene is yebA [C]

Identifier: 126207941

GI number: 126207941

Start: 527966

End: 529456

Strand: Direct

Name: yebA [C]

Synonym: APL_0457

Alternate gene names: 126207941

Gene position: 527966-529456 (Clockwise)

Preceding gene: 126207934

Following gene: 126207942

Centisome position: 23.21

GC content: 42.52

Gene sequence:

>1491_bases
ATGGCGATCTTATCAATTTTTATTGGTATTGTACTTGCGTTAAAAAATCAACCTTCTATAAATACAACGGCGAATTACGA
ACAATACGTTGTATTGGACGAGCAACAAGCGGATCAAAAAGATGATCCGGAACAACCGGAAGAGACGACACAATTAACAT
CCGCAGAAGATCAGAAACAAGCGGCGGATAAGACATCTACTAATAATGTAAATACGGAAGCTAATGAAGAAGTTTCCGAA
GACGAGAAAAATTCGGAATTAACCGCAGAAGATAATTCCGCAACCTCTTATGATGATCTTTTAGCTGAAGATGATGAGGT
TGAAGGGCAAGAGGGTGAGATCTCTAAAGTCGAAAATAAAGAGAATGAAGAAAAGTTGCCTCAAGAGGCCGAGAAAGTCT
TAAACGATATTTTAGACGTCGCGGACGAAGCGTTACGCATTCAGGATCAATTCAGTTATACCGTCGGTCGCGGTGATAAG
CTCAAAGATGTTTTGGAGCAGTCCGGTTTAGGTGCAAGTGATGCCAGAGCTATGATTAAACGTTTTCCGGAATTGGCTAA
TTTAGACGGCGGTCAGCAATTCTACTGGATTTTGGATAACCACGGCGAGTTGGAATATATGAACTGGTTGGTATCTGAAA
AAGAAGAACGTATTTATGAGCGTAAAGATAACGGTAAATGGGTCTTTCAAAAAATAGAGAAGAAAGGCGAATGGCGACAA
GATGTGGTACGTGGTGTAATTAGCGGTTCTTTTTCTTCAAGTCTTAAAGAAGTGGGGCTTTCGGAACGGCAAGTAAATCA
GTTGGCGGTCGGATTGCAGTCACAAATTGCAACTAATAAACTGAAAAAAGGTGATCGTTTCGCTATCTTGGTAAAACGTG
AATACATCAACGGTACGGTAACGGAAGTCGGCAACGTAGAAGGCATCCTGATTGTCAGCGACAAGAAACGTTATTATGCG
ATTCAAGCGGATAACGGACGTTATTACAGTAGCCACGGTGAAACCCTCAGCAGAGGATTTGCCCGTATTCCTTTGTTATT
TAATGCAAGGGTATCATCGCACTATAATCCTAGACGTTTACATCCGGTCACGCGCAGAGTCAGACCGCATAACGGGGTGG
ATTTCGGCATACCGACGGGAACGCCGATTATCGCACCGTCGGACGGTGTGGTTGAACATATCGCTTATCAGGCAAAAGGT
GCGGGGCGCTATATTAAAATTCGTCACGGTCACATTACCACGGTTTATATGCACTTAAGTAAAACGTTGGTGAGAGTCGG
ACAAAGTGTGAAAAAAGGTGAGCGTATTGCGTTATCGGGAAATACGGGAGCTTCTACGGGACCTCATTTACACTATGAAT
TCCATCTTAACGGAAGACCGGTTAATCCGATGACGGTGAAATTACCCGGTTCAAATTCGGGTATGGCGGATAAAGAACGT
AAGAAGTTCTTAACGCGTGCTAAATATGTTGAAGCAAAATTAAAATTTTAA

Upstream 100 bases:

>100_bases
GTAAGAAATAAATGATACGATAGGACATATTTTGCAACACGTTATATTGGCAAGAGATCGACGTCGGAAAAAATCTCGGT
TAAAAGGTTTGGTTTTTTTG

Downstream 100 bases:

>100_bases
TTTATAGGATATTTAATCATGAAAAAAAATGTAACGGCATTATTTTCCGTTTCTTTAATGGGCTTATGCGTATCTCCCGT
GATGGCTGATGATATGAGCT

Product: metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MAILSIFIGIVLALKNQPSINTTANYEQYVVLDEQQADQKDDPEQPEETTQLTSAEDQKQAADKTSTNNVNTEANEEVSE
DEKNSELTAEDNSATSYDDLLAEDDEVEGQEGEISKVENKENEEKLPQEAEKVLNDILDVADEALRIQDQFSYTVGRGDK
LKDVLEQSGLGASDARAMIKRFPELANLDGGQQFYWILDNHGELEYMNWLVSEKEERIYERKDNGKWVFQKIEKKGEWRQ
DVVRGVISGSFSSSLKEVGLSERQVNQLAVGLQSQIATNKLKKGDRFAILVKREYINGTVTEVGNVEGILIVSDKKRYYA
IQADNGRYYSSHGETLSRGFARIPLLFNARVSSHYNPRRLHPVTRRVRPHNGVDFGIPTGTPIIAPSDGVVEHIAYQAKG
AGRYIKIRHGHITTVYMHLSKTLVRVGQSVKKGERIALSGNTGASTGPHLHYEFHLNGRPVNPMTVKLPGSNSGMADKER
KKFLTRAKYVEAKLKF

Sequences:

>Translated_496_residues
MAILSIFIGIVLALKNQPSINTTANYEQYVVLDEQQADQKDDPEQPEETTQLTSAEDQKQAADKTSTNNVNTEANEEVSE
DEKNSELTAEDNSATSYDDLLAEDDEVEGQEGEISKVENKENEEKLPQEAEKVLNDILDVADEALRIQDQFSYTVGRGDK
LKDVLEQSGLGASDARAMIKRFPELANLDGGQQFYWILDNHGELEYMNWLVSEKEERIYERKDNGKWVFQKIEKKGEWRQ
DVVRGVISGSFSSSLKEVGLSERQVNQLAVGLQSQIATNKLKKGDRFAILVKREYINGTVTEVGNVEGILIVSDKKRYYA
IQADNGRYYSSHGETLSRGFARIPLLFNARVSSHYNPRRLHPVTRRVRPHNGVDFGIPTGTPIIAPSDGVVEHIAYQAKG
AGRYIKIRHGHITTVYMHLSKTLVRVGQSVKKGERIALSGNTGASTGPHLHYEFHLNGRPVNPMTVKLPGSNSGMADKER
KKFLTRAKYVEAKLKF
>Mature_495_residues
AILSIFIGIVLALKNQPSINTTANYEQYVVLDEQQADQKDDPEQPEETTQLTSAEDQKQAADKTSTNNVNTEANEEVSED
EKNSELTAEDNSATSYDDLLAEDDEVEGQEGEISKVENKENEEKLPQEAEKVLNDILDVADEALRIQDQFSYTVGRGDKL
KDVLEQSGLGASDARAMIKRFPELANLDGGQQFYWILDNHGELEYMNWLVSEKEERIYERKDNGKWVFQKIEKKGEWRQD
VVRGVISGSFSSSLKEVGLSERQVNQLAVGLQSQIATNKLKKGDRFAILVKREYINGTVTEVGNVEGILIVSDKKRYYAI
QADNGRYYSSHGETLSRGFARIPLLFNARVSSHYNPRRLHPVTRRVRPHNGVDFGIPTGTPIIAPSDGVVEHIAYQAKGA
GRYIKIRHGHITTVYMHLSKTLVRVGQSVKKGERIALSGNTGASTGPHLHYEFHLNGRPVNPMTVKLPGSNSGMADKERK
KFLTRAKYVEAKLKF

Specific function: Could Be Involved In Cell Wall Degradation Or Formation. [C]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

Organism=Escherichia coli, GI87081989, Length=395, Percent_Identity=41.7721518987342, Blast_Score=299, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR007340
- InterPro:   IPR016047
- InterPro:   IPR002886 [H]

Pfam domain/function: PF04225 OapA; PF01551 Peptidase_M23 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 55627; Mature: 55496

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILSIFIGIVLALKNQPSINTTANYEQYVVLDEQQADQKDDPEQPEETTQLTSAEDQKQ
CHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHCCCCCCCCCCHHHHHHCCCHHHHH
AADKTSTNNVNTEANEEVSEDEKNSELTAEDNSATSYDDLLAEDDEVEGQEGEISKVENK
HHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHCCC
ENEEKLPQEAEKVLNDILDVADEALRIQDQFSYTVGRGDKLKDVLEQSGLGASDARAMIK
CCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCHHHHHHHHH
RFPELANLDGGQQFYWILDNHGELEYMNWLVSEKEERIYERKDNGKWVFQKIEKKGEWRQ
HCHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
DVVRGVISGSFSSSLKEVGLSERQVNQLAVGLQSQIATNKLKKGDRFAILVKREYINGTV
HHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
TEVGNVEGILIVSDKKRYYAIQADNGRYYSSHGETLSRGFARIPLLFNARVSSHYNPRRL
EECCCCCEEEEEECCCEEEEEEECCCEEECCCCCHHHCCHHHCCEEEECHHHCCCCCCCC
HPVTRRVRPHNGVDFGIPTGTPIIAPSDGVVEHIAYQAKGAGRYIKIRHGHITTVYMHLS
CHHHHHCCCCCCCEECCCCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCEEEEHHHHH
KTLVRVGQSVKKGERIALSGNTGASTGPHLHYEFHLNGRPVNPMTVKLPGSNSGMADKER
HHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHH
KKFLTRAKYVEAKLKF
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AILSIFIGIVLALKNQPSINTTANYEQYVVLDEQQADQKDDPEQPEETTQLTSAEDQKQ
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHCCCCCCCCCCHHHHHHCCCHHHHH
AADKTSTNNVNTEANEEVSEDEKNSELTAEDNSATSYDDLLAEDDEVEGQEGEISKVENK
HHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHCCC
ENEEKLPQEAEKVLNDILDVADEALRIQDQFSYTVGRGDKLKDVLEQSGLGASDARAMIK
CCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCHHHHHHHHH
RFPELANLDGGQQFYWILDNHGELEYMNWLVSEKEERIYERKDNGKWVFQKIEKKGEWRQ
HCHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
DVVRGVISGSFSSSLKEVGLSERQVNQLAVGLQSQIATNKLKKGDRFAILVKREYINGTV
HHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
TEVGNVEGILIVSDKKRYYAIQADNGRYYSSHGETLSRGFARIPLLFNARVSSHYNPRRL
EECCCCCEEEEEECCCEEEEEEECCCEEECCCCCHHHCCHHHCCEEEECHHHCCCCCCCC
HPVTRRVRPHNGVDFGIPTGTPIIAPSDGVVEHIAYQAKGAGRYIKIRHGHITTVYMHLS
CHHHHHCCCCCCCEECCCCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCEEEEHHHHH
KTLVRVGQSVKKGERIALSGNTGASTGPHLHYEFHLNGRPVNPMTVKLPGSNSGMADKER
HHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHH
KKFLTRAKYVEAKLKF
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]