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The map label for this gene is menC [H]

Identifier: 126207837

GI number: 126207837

Start: 395906

End: 396868

Strand: Direct

Name: menC [H]

Synonym: APL_0353

Alternate gene names: 126207837

Gene position: 395906-396868 (Clockwise)

Preceding gene: 126207834

Following gene: 126207838

Centisome position: 17.41

GC content: 46.0

Gene sequence:

>963_bases
ATGAGAAAAGCCGAACTTTACCGCTATGCGATTCCTTGTCAAACCGGCGTGGTATTACGCAAGCAACCGCTCATTCAACG
AGAAGGGCTGATTCTTAAACTGGAAGAAAACGGCAAAATCGGCTTAGGCGAAATTGCTCCCTTGCCCGGTTTTAGTCAAG
AAACATTAGCCGATGCGGAAATGCAAGCGAAGATGTGGTTAGCGAATCAAACCGATGATTTGGAAGAATTATTTCCTTCG
GTTGCGTTTGGTATTAGTTGTGCATTGGCTGAATTGCGTAATGAATTGATTACTCAGGGAAAGTTTGCTTCGGCAATTTT
ATGCGACGGTAATTTTACGCAGTTTGCGCAAAAAATCGCACGAATTCCGCAGCCGCTCGGCAAAATCAAAATCGGCTTCG
AGCCGGAAAAGGAAGGCGAGTTGGCAAATAGGTTGTTGGAACAATTCCCACATCTTACCTTGCGTTTGGATGCCAATCGC
AGTTTTTCGTTGGCGCAAGCGGTCGGATTTGGTAAAAAAATTGCAAAATCGAACCGCTTGCGTATCCAATTTATTGAAGA
ACCCTGTTTTACCCCCTCGTTCTCTCGTCAATTCGCACAAGCAACCGGTATTGCGATAGCGTGGGATGAAAGCGTACGTG
AAGCGGGATTCAACGTAAAAGCGGAAGATTATTTGAAAGCGATAGTGATTAAACCGACCCTTACCGGCTCGCTTGCCAAA
TGTGTGAATTTAATCAAGCAGGCACATACGCAAGGATTGAAAGCGGTTATCAGTTCTAGCCTTGAAAGCAGTTTGGGATT
ATCGCAGTTGGCAAGAATTGCCGCACAATACACACCGGAAACGGTAGCGGGGCTAGACACGCTCGGCTTAATGCAAGTGC
AGCTGGTTCGAGCGTGGCAGGGGGCGGATTTACCTTTAGCGGGATTACAAAGTCGGTTTTTGCAAAAAATTGCTGAAATT
TGA

Upstream 100 bases:

>100_bases
AATATTCTTTTAATTTTAGCTTAAACGGGCTTTTTTTTCCAGTTTCAATTATATGCGGCAAGCGGTAGAATTTAGGCAAA
ATTTTACAAACGGACAGAAA

Downstream 100 bases:

>100_bases
CCGCTTGTTTTATATAAGTTAAGACCGGCTTAGTGTTATTTTTTCAACACGGTTTGAATTAACAGCAAAATTGCCGCCGC
ATCATCAACCAAACCGAGCG

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MRKAELYRYAIPCQTGVVLRKQPLIQREGLILKLEENGKIGLGEIAPLPGFSQETLADAEMQAKMWLANQTDDLEELFPS
VAFGISCALAELRNELITQGKFASAILCDGNFTQFAQKIARIPQPLGKIKIGFEPEKEGELANRLLEQFPHLTLRLDANR
SFSLAQAVGFGKKIAKSNRLRIQFIEEPCFTPSFSRQFAQATGIAIAWDESVREAGFNVKAEDYLKAIVIKPTLTGSLAK
CVNLIKQAHTQGLKAVISSSLESSLGLSQLARIAAQYTPETVAGLDTLGLMQVQLVRAWQGADLPLAGLQSRFLQKIAEI

Sequences:

>Translated_320_residues
MRKAELYRYAIPCQTGVVLRKQPLIQREGLILKLEENGKIGLGEIAPLPGFSQETLADAEMQAKMWLANQTDDLEELFPS
VAFGISCALAELRNELITQGKFASAILCDGNFTQFAQKIARIPQPLGKIKIGFEPEKEGELANRLLEQFPHLTLRLDANR
SFSLAQAVGFGKKIAKSNRLRIQFIEEPCFTPSFSRQFAQATGIAIAWDESVREAGFNVKAEDYLKAIVIKPTLTGSLAK
CVNLIKQAHTQGLKAVISSSLESSLGLSQLARIAAQYTPETVAGLDTLGLMQVQLVRAWQGADLPLAGLQSRFLQKIAEI
>Mature_320_residues
MRKAELYRYAIPCQTGVVLRKQPLIQREGLILKLEENGKIGLGEIAPLPGFSQETLADAEMQAKMWLANQTDDLEELFPS
VAFGISCALAELRNELITQGKFASAILCDGNFTQFAQKIARIPQPLGKIKIGFEPEKEGELANRLLEQFPHLTLRLDANR
SFSLAQAVGFGKKIAKSNRLRIQFIEEPCFTPSFSRQFAQATGIAIAWDESVREAGFNVKAEDYLKAIVIKPTLTGSLAK
CVNLIKQAHTQGLKAVISSSLESSLGLSQLARIAAQYTPETVAGLDTLGLMQVQLVRAWQGADLPLAGLQSRFLQKIAEI

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=310, Percent_Identity=50.9677419354839, Blast_Score=290, Evalue=9e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 35141; Mature: 35141

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAELYRYAIPCQTGVVLRKQPLIQREGLILKLEENGKIGLGEIAPLPGFSQETLADAE
CCCCHHEEEECCCCCCEEECCCCCHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
MQAKMWLANQTDDLEELFPSVAFGISCALAELRNELITQGKFASAILCDGNFTQFAQKIA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
RIPQPLGKIKIGFEPEKEGELANRLLEQFPHLTLRLDANRSFSLAQAVGFGKKIAKSNRL
HCCCCHHCEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCE
RIQFIEEPCFTPSFSRQFAQATGIAIAWDESVREAGFNVKAEDYLKAIVIKPTLTGSLAK
EEEEECCCCCCCHHHHHHHHHCCEEEEECHHHHHCCCCCCHHHHHEEEEECCCCCHHHHH
CVNLIKQAHTQGLKAVISSSLESSLGLSQLARIAAQYTPETVAGLDTLGLMQVQLVRAWQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GADLPLAGLQSRFLQKIAEI
CCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKAELYRYAIPCQTGVVLRKQPLIQREGLILKLEENGKIGLGEIAPLPGFSQETLADAE
CCCCHHEEEECCCCCCEEECCCCCHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
MQAKMWLANQTDDLEELFPSVAFGISCALAELRNELITQGKFASAILCDGNFTQFAQKIA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
RIPQPLGKIKIGFEPEKEGELANRLLEQFPHLTLRLDANRSFSLAQAVGFGKKIAKSNRL
HCCCCHHCEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCE
RIQFIEEPCFTPSFSRQFAQATGIAIAWDESVREAGFNVKAEDYLKAIVIKPTLTGSLAK
EEEEECCCCCCCHHHHHHHHHCCEEEEECHHHHHCCCCCCHHHHHEEEEECCCCCHHHHH
CVNLIKQAHTQGLKAVISSSLESSLGLSQLARIAAQYTPETVAGLDTLGLMQVQLVRAWQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GADLPLAGLQSRFLQKIAEI
CCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA