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The map label for this gene is pgsA [H]

Identifier: 126207763

GI number: 126207763

Start: 302222

End: 302773

Strand: Direct

Name: pgsA [H]

Synonym: APL_0275

Alternate gene names: 126207763

Gene position: 302222-302773 (Clockwise)

Preceding gene: 126207758

Following gene: 126207764

Centisome position: 13.29

GC content: 40.76

Gene sequence:

>552_bases
ATGAAACTAAATTTTCCTACCTATTTAACCTTATTTCGGGTCGTGTTAATTCCTCTGTTCGTCATTGCTTTTTATTTGCC
TGCCGGTTGGTATGCCGCTGAAATTTCAACGCTGATTTTTTTTATTGCGTCCATTACCGATGCTTTTGACGGTTATTTGG
CAAGAAAGTGGAATCAAACTACTCAATTAGGTGCGTTTTTAGATCCGGTTGCAGATAAAGTATTGGTTGCGGTGGCATTA
GTATGTGTAGTGGAATATTACCATACGTGGTGGATTTCTATTCCGGCGGCAATTATGATTGCGAGAGAAATTATTATTTC
GGCATTGAGAGAATGGATGGCGGAATTAGGCGAACGCGCCAGTGTAGCAGTTTCTATGTGGGGAAAATTTAAAACCACCG
CACAAATGTTGGCGCTTGGCGGAATGTTGTGGCGGTTTAATTTTGCGATGGAAGTGCTTGCTTGGATTTTACTGTATATT
GCCGCCGGTTTAACGCTCTGGTCAATGATGCAATATTTAAATGCGGCAAAAGGCAGTTTATTAAAATCGTAA

Upstream 100 bases:

>100_bases
TAGCCAAAGTCAATTGACTTTATCTATACAATAGTTAAAAATTTTCTTATGAGTGTGATACACTTAGATAACCGAACGTT
TACTTTGCAAATGCCACTAT

Downstream 100 bases:

>100_bases
TTAAAGAGAACCGAAACGATATAAGCGAGATAATATCTCGCTTTTTTTATGCGTAAAATAAATTGAAATGACAATTGTTT
TTATTTAAACTTAAGACCTT

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKLNFPTYLTLFRVVLIPLFVIAFYLPAGWYAAEISTLIFFIASITDAFDGYLARKWNQTTQLGAFLDPVADKVLVAVAL
VCVVEYYHTWWISIPAAIMIAREIIISALREWMAELGERASVAVSMWGKFKTTAQMLALGGMLWRFNFAMEVLAWILLYI
AAGLTLWSMMQYLNAAKGSLLKS

Sequences:

>Translated_183_residues
MKLNFPTYLTLFRVVLIPLFVIAFYLPAGWYAAEISTLIFFIASITDAFDGYLARKWNQTTQLGAFLDPVADKVLVAVAL
VCVVEYYHTWWISIPAAIMIAREIIISALREWMAELGERASVAVSMWGKFKTTAQMLALGGMLWRFNFAMEVLAWILLYI
AAGLTLWSMMQYLNAAKGSLLKS
>Mature_183_residues
MKLNFPTYLTLFRVVLIPLFVIAFYLPAGWYAAEISTLIFFIASITDAFDGYLARKWNQTTQLGAFLDPVADKVLVAVAL
VCVVEYYHTWWISIPAAIMIAREIIISALREWMAELGERASVAVSMWGKFKTTAQMLALGGMLWRFNFAMEVLAWILLYI
AAGLTLWSMMQYLNAAKGSLLKS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=183, Percent_Identity=63.9344262295082, Blast_Score=234, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20664; Mature: 20664

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNFPTYLTLFRVVLIPLFVIAFYLPAGWYAAEISTLIFFIASITDAFDGYLARKWNQT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TQLGAFLDPVADKVLVAVALVCVVEYYHTWWISIPAAIMIAREIIISALREWMAELGERA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SVAVSMWGKFKTTAQMLALGGMLWRFNFAMEVLAWILLYIAAGLTLWSMMQYLNAAKGSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKS
CCC
>Mature Secondary Structure
MKLNFPTYLTLFRVVLIPLFVIAFYLPAGWYAAEISTLIFFIASITDAFDGYLARKWNQT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TQLGAFLDPVADKVLVAVALVCVVEYYHTWWISIPAAIMIAREIIISALREWMAELGERA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SVAVSMWGKFKTTAQMLALGGMLWRFNFAMEVLAWILLYIAAGLTLWSMMQYLNAAKGSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]