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The map label for this gene is suhB [H]

Identifier: 126207694

GI number: 126207694

Start: 224692

End: 225504

Strand: Direct

Name: suhB [H]

Synonym: APL_0206

Alternate gene names: 126207694

Gene position: 224692-225504 (Clockwise)

Preceding gene: 126207692

Following gene: 126207695

Centisome position: 9.88

GC content: 45.76

Gene sequence:

>813_bases
ATGAACCCAATGTTAAACATTGCTATTCGTGCTGCACGAAAAGCAGGCAATATTATTGCGAAAGGCTATGAGCAAGCCGC
GAGTGAAATCGAAGTGGCTCAAAAAGGTACAAACGATTACGTAACGGCAATTGATAAAGCGGCGGAAGCGGCGATTATCG
AAGTAATCCGTAAATCTTATCCTGATCATGCGATTGTCGGCGAAGAGTCAGGTATTTTGGCAGGCGAAAACGAAAATGTG
CAATGGGTGATTGATCCATTAGACGGTACAACTAACTTCGTAAAACGTTTGCCTCATTTTGCAGTATCTATCGCAGTGCG
TGAAAACGGTCGTACCACGGTGGGAGTGGTTTACGATCCAATTCGTAACGAACTTTTCACCGCCGTACGCGGTGAAGGTG
CAAAACTCAATGAATTCCGTTTACGTGTAGAAACGGAACGTCGCGATTTAAACGGTACCGTACTTGCAACCGGTTTTCCT
TTCAAAGCGGCTAAACATCGTCCGGCGCATTTAAATATGCTCGAAGGCTTAATGAATAACGGCGTGGCGGATTTCCGTCG
TACCGGTTCCGCGGCACTTGATTTGGCTTATGTTGCGGCAAATCGTGTGGACGGTTACTTTGAAATCGGTTTAAAACCGT
GGGATTGTGCGGCGGGTGATTTAATTGTGCGTGAAGCGGGTGCAATCGTGACGAATTTTGTCGGCGGTACGGACTACTTA
AAATCAGGTAATGTCGTAGCAGGTCAGGCTCGTGTGGTAAAAGAAATCCTAAATGCGATTCAACCGACATTAACCGAAGA
TCTTAAAAACTAA

Upstream 100 bases:

>100_bases
TGCAAAAAATTTTGCGAATCGGACCGCTTGTTATTTCTTTATTTATCGAGTTTCTTTATAATCGGTTGTCTTTTTATGTT
CTTTAAAATCCGGTGGAATT

Downstream 100 bases:

>100_bases
TTTAAAATTTAAACCATAGATTACACGGATAAGGCAAGTAAGCGGTCGAATTTTCCGCTTATTTTGCAATATCCGTGTTA
ATTCGTGTGGGACGTGGGTT

Product: inositol-1-monophosphatase (IMPase)

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MNPMLNIAIRAARKAGNIIAKGYEQAASEIEVAQKGTNDYVTAIDKAAEAAIIEVIRKSYPDHAIVGEESGILAGENENV
QWVIDPLDGTTNFVKRLPHFAVSIAVRENGRTTVGVVYDPIRNELFTAVRGEGAKLNEFRLRVETERRDLNGTVLATGFP
FKAAKHRPAHLNMLEGLMNNGVADFRRTGSAALDLAYVAANRVDGYFEIGLKPWDCAAGDLIVREAGAIVTNFVGGTDYL
KSGNVVAGQARVVKEILNAIQPTLTEDLKN

Sequences:

>Translated_270_residues
MNPMLNIAIRAARKAGNIIAKGYEQAASEIEVAQKGTNDYVTAIDKAAEAAIIEVIRKSYPDHAIVGEESGILAGENENV
QWVIDPLDGTTNFVKRLPHFAVSIAVRENGRTTVGVVYDPIRNELFTAVRGEGAKLNEFRLRVETERRDLNGTVLATGFP
FKAAKHRPAHLNMLEGLMNNGVADFRRTGSAALDLAYVAANRVDGYFEIGLKPWDCAAGDLIVREAGAIVTNFVGGTDYL
KSGNVVAGQARVVKEILNAIQPTLTEDLKN
>Mature_270_residues
MNPMLNIAIRAARKAGNIIAKGYEQAASEIEVAQKGTNDYVTAIDKAAEAAIIEVIRKSYPDHAIVGEESGILAGENENV
QWVIDPLDGTTNFVKRLPHFAVSIAVRENGRTTVGVVYDPIRNELFTAVRGEGAKLNEFRLRVETERRDLNGTVLATGFP
FKAAKHRPAHLNMLEGLMNNGVADFRRTGSAALDLAYVAANRVDGYFEIGLKPWDCAAGDLIVREAGAIVTNFVGGTDYL
KSGNVVAGQARVVKEILNAIQPTLTEDLKN

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=260, Percent_Identity=35.3846153846154, Blast_Score=154, Evalue=5e-38,
Organism=Homo sapiens, GI221625487, Length=260, Percent_Identity=35.3846153846154, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI7657236, Length=252, Percent_Identity=36.5079365079365, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI221625507, Length=148, Percent_Identity=39.1891891891892, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1788882, Length=269, Percent_Identity=66.1710037174721, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1790659, Length=148, Percent_Identity=35.1351351351351, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193202570, Length=261, Percent_Identity=31.8007662835249, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI193202572, Length=258, Percent_Identity=30.2325581395349, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320493, Length=211, Percent_Identity=34.1232227488152, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6321836, Length=234, Percent_Identity=33.7606837606838, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24664922, Length=262, Percent_Identity=33.587786259542, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI21357329, Length=274, Percent_Identity=34.3065693430657, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24664926, Length=261, Percent_Identity=31.8007662835249, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24664918, Length=262, Percent_Identity=34.7328244274809, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21357957, Length=267, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI21357303, Length=262, Percent_Identity=30.5343511450382, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29247; Mature: 29247

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPMLNIAIRAARKAGNIIAKGYEQAASEIEVAQKGTNDYVTAIDKAAEAAIIEVIRKSY
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
PDHAIVGEESGILAGENENVQWVIDPLDGTTNFVKRLPHFAVSIAVRENGRTTVGVVYDP
CCCEEECCCCCEEECCCCCEEEEEECCCCHHHHHHHCCHHEEEEEEECCCCEEEEEEECH
IRNELFTAVRGEGAKLNEFRLRVETERRDLNGTVLATGFPFKAAKHRPAHLNMLEGLMNN
HHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHC
GVADFRRTGSAALDLAYVAANRVDGYFEIGLKPWDCAAGDLIVREAGAIVTNFVGGTDYL
CHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEHHHCHHHHHHCCCCHHH
KSGNVVAGQARVVKEILNAIQPTLTEDLKN
CCCCEEEHHHHHHHHHHHHHCHHHHHHHCC
>Mature Secondary Structure
MNPMLNIAIRAARKAGNIIAKGYEQAASEIEVAQKGTNDYVTAIDKAAEAAIIEVIRKSY
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
PDHAIVGEESGILAGENENVQWVIDPLDGTTNFVKRLPHFAVSIAVRENGRTTVGVVYDP
CCCEEECCCCCEEECCCCCEEEEEECCCCHHHHHHHCCHHEEEEEEECCCCEEEEEEECH
IRNELFTAVRGEGAKLNEFRLRVETERRDLNGTVLATGFPFKAAKHRPAHLNMLEGLMNN
HHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHC
GVADFRRTGSAALDLAYVAANRVDGYFEIGLKPWDCAAGDLIVREAGAIVTNFVGGTDYL
CHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEHHHCHHHHHHCCCCHHH
KSGNVVAGQARVVKEILNAIQPTLTEDLKN
CCCCEEEHHHHHHHHHHHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]