BacMap

Definition	Actinobacillus pleuropneumoniae serovar 5b str. L20 chromosome, complete genome.
Accession	NC_009053
Length	2,274,482

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The map label for this gene is 126207679

Identifier: 126207679

GI number: 126207679

Start: 210408

End: 211766

Strand: Reverse

Name: 126207679

Synonym: APL_0191

Alternate gene names: NA

Gene position: 211766-210408 (Counterclockwise)

Preceding gene: 126207680

Following gene: 126207675

Centisome position: 9.31

GC content: 40.4

Gene sequence:

>1359_bases
ATGGCGAATAAATCTGTAGAACGCCAATCTTGGTCAAATAGATTGGCTTATGTGATGACGGTTGCAGGGGCGACCGTCGG
TTTCGGGGCGACTTGGCGTTTTCCTTATTTAGTCGGAGAAAACGGCGGCGGTGCCTATGTATTTTTATTTTGTATTGCGA
TGATTGTGATCGGTATTCCGATGATTTTGGTTGAAAACGTTATCGGTCGTCGTATTAAAGTCAATGCAATCGATGCTTTC
GGCGGAATGGCAAACGGTAAAAAAATTGCTTCGGGTTGGAAAATTCTCGGTTATATGGGCTTACTCGGTGCTTTCGGTAT
CTTAGCCTACTATATGGTACTGGGCGGTTGGGTATTAAATTATATCAGCAGTTTAATTAGCGGCACTTTAGATCTTTCCA
CTCCGGTTACGGTTGAAACAACCGCATCTTACTATAAGGAAAGCATCCAAAACAGCCCGATGGCGATTATCGGTTATACC
GCTTTATTCGTCTTGGTAAACTATTTTATTTTGAGTAAAGGGATCGTGGACGGTATTGAACGTTCGGTTAAATACCTTAT
GCCGTTACTCTTTGTCTTCTTACTTGTCATGGTTATTCGCAATGTTACCCTACCGGGAGCGGCGGAAGGGATCGCATTTT
ATCTAATGCCCGATTTTTCTAAAATTACGCCGAAACTTTTCGTATTCGTATTGGGGCAAGTATTCTTTGCGTTAAGCCTC
GGTTTCGGTGTATTAATCACACTTTCCAGCTATTTGGATAAAAATGAGAATTTAGTTAAAACCGCTACCATTACCGGTAT
TATGAATACCTTGATTGCGGTACTCGCCGGTTTTATGATTTTCCCGTCATTATTTAGTTTTGGCGTGGCACCGAATTCAG
GCCCTACGTTGGTTTTCCAAAGTTTGCCGATTGTCTTCTCTAATATGTGGGGCGGAACACTTTTTGCCATTATTTTCTTC
AGTTTACTCGTTGTAGCGGCACTTACGACGTCCTTAACGATTTATGAAGTAATTATTACCGCTTTACAAGAAAAAACCAA
AATGAGCCGTAAAAAGGCGATTGCGGTTACGTTATCTACGATTTTTGTGATTGGCAATATTCCGTCGGTCTTAGGCGACA
ATCTCTGGCAACATATTCGTATTATGGATAAAAGTATTTTTGACGCTTTCGACTATATCAGCGGCAATATTCTGTTTATT
CTTACCGCATTAGGCAGTGCGATTTTTGTGGGATTTGTGTTAAAAGATGAAGCGAAAAAAGAATTGGGTGCGGGAAAAGT
CTTCACGAATATTTGGTTCAATTACGTTAAATTCGTGATTCCGGTTATTATCTTAGTGATTTTCTTTAATTCGTTATAA

Upstream 100 bases:

>100_bases
ATTAAAGTAGATGAACTGTTTGCACTCTTCTTATAATTTGCAAAAATTTCTTAAAATCTTACCGCTTGCTTTGCGGAAAT
AGCCTAACTTAGGAGTAATA

Downstream 100 bases:

>100_bases
ACAAAATACAAAAAAGGCTATTCAACGGAATAGCCTTTTTTATGGAAAAAATATGAGTTAAAAATTAACCCATACCGTAT
TTTTTTAATTTTTTGCGTAA

Product: SNF family Na+-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MANKSVERQSWSNRLAYVMTVAGATVGFGATWRFPYLVGENGGGAYVFLFCIAMIVIGIPMILVENVIGRRIKVNAIDAF
GGMANGKKIASGWKILGYMGLLGAFGILAYYMVLGGWVLNYISSLISGTLDLSTPVTVETTASYYKESIQNSPMAIIGYT
ALFVLVNYFILSKGIVDGIERSVKYLMPLLFVFLLVMVIRNVTLPGAAEGIAFYLMPDFSKITPKLFVFVLGQVFFALSL
GFGVLITLSSYLDKNENLVKTATITGIMNTLIAVLAGFMIFPSLFSFGVAPNSGPTLVFQSLPIVFSNMWGGTLFAIIFF
SLLVVAALTTSLTIYEVIITALQEKTKMSRKKAIAVTLSTIFVIGNIPSVLGDNLWQHIRIMDKSIFDAFDYISGNILFI
LTALGSAIFVGFVLKDEAKKELGAGKVFTNIWFNYVKFVIPVIILVIFFNSL

Sequences:

>Translated_452_residues
MANKSVERQSWSNRLAYVMTVAGATVGFGATWRFPYLVGENGGGAYVFLFCIAMIVIGIPMILVENVIGRRIKVNAIDAF
GGMANGKKIASGWKILGYMGLLGAFGILAYYMVLGGWVLNYISSLISGTLDLSTPVTVETTASYYKESIQNSPMAIIGYT
ALFVLVNYFILSKGIVDGIERSVKYLMPLLFVFLLVMVIRNVTLPGAAEGIAFYLMPDFSKITPKLFVFVLGQVFFALSL
GFGVLITLSSYLDKNENLVKTATITGIMNTLIAVLAGFMIFPSLFSFGVAPNSGPTLVFQSLPIVFSNMWGGTLFAIIFF
SLLVVAALTTSLTIYEVIITALQEKTKMSRKKAIAVTLSTIFVIGNIPSVLGDNLWQHIRIMDKSIFDAFDYISGNILFI
LTALGSAIFVGFVLKDEAKKELGAGKVFTNIWFNYVKFVIPVIILVIFFNSL
>Mature_451_residues
ANKSVERQSWSNRLAYVMTVAGATVGFGATWRFPYLVGENGGGAYVFLFCIAMIVIGIPMILVENVIGRRIKVNAIDAFG
GMANGKKIASGWKILGYMGLLGAFGILAYYMVLGGWVLNYISSLISGTLDLSTPVTVETTASYYKESIQNSPMAIIGYTA
LFVLVNYFILSKGIVDGIERSVKYLMPLLFVFLLVMVIRNVTLPGAAEGIAFYLMPDFSKITPKLFVFVLGQVFFALSLG
FGVLITLSSYLDKNENLVKTATITGIMNTLIAVLAGFMIFPSLFSFGVAPNSGPTLVFQSLPIVFSNMWGGTLFAIIFFS
LLVVAALTTSLTIYEVIITALQEKTKMSRKKAIAVTLSTIFVIGNIPSVLGDNLWQHIRIMDKSIFDAFDYISGNILFIL
TALGSAIFVGFVLKDEAKKELGAGKVFTNIWFNYVKFVIPVIILVIFFNSL

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=407, Percent_Identity=28.009828009828, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI188528618, Length=387, Percent_Identity=27.6485788113695, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI7657587, Length=482, Percent_Identity=26.5560165975104, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI21361581, Length=487, Percent_Identity=26.2833675564682, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI171184408, Length=414, Percent_Identity=26.0869565217391, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI171184406, Length=414, Percent_Identity=26.0869565217391, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI171184404, Length=414, Percent_Identity=26.0869565217391, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI51468073, Length=303, Percent_Identity=28.3828382838284, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI289191351, Length=407, Percent_Identity=27.5184275184275, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI4557046, Length=407, Percent_Identity=27.5184275184275, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI289191377, Length=407, Percent_Identity=27.5184275184275, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI33354281, Length=300, Percent_Identity=29.6666666666667, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4507041, Length=410, Percent_Identity=26.0975609756098, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI58219014, Length=300, Percent_Identity=30, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI197276623, Length=347, Percent_Identity=28.2420749279539, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI54607094, Length=347, Percent_Identity=28.2420749279539, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI5032097, Length=419, Percent_Identity=27.6849642004773, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI194018524, Length=298, Percent_Identity=27.5167785234899, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI134304856, Length=316, Percent_Identity=27.8481012658228, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI11181770, Length=308, Percent_Identity=27.2727272727273, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI67782317, Length=423, Percent_Identity=27.1867612293144, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI67782313, Length=423, Percent_Identity=27.4231678486998, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI67782315, Length=423, Percent_Identity=27.4231678486998, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI218563756, Length=419, Percent_Identity=26.7303102625298, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI12408638, Length=285, Percent_Identity=26.3157894736842, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI6005715, Length=355, Percent_Identity=26.1971830985915, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI300360519, Length=289, Percent_Identity=27.3356401384083, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI289191353, Length=209, Percent_Identity=31.1004784688995, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI21361693, Length=147, Percent_Identity=30.6122448979592, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI92859670, Length=199, Percent_Identity=31.1557788944724, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI55749589, Length=288, Percent_Identity=23.9583333333333, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI197276625, Length=145, Percent_Identity=30.3448275862069, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI218563758, Length=220, Percent_Identity=32.7272727272727, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI226437581, Length=252, Percent_Identity=25.7936507936508, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=425, Percent_Identity=28.4705882352941, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25146584, Length=453, Percent_Identity=24.9448123620309, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71995588, Length=420, Percent_Identity=24.7619047619048, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17554804, Length=492, Percent_Identity=24.5934959349593, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17569475, Length=399, Percent_Identity=23.3082706766917, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI133952791, Length=215, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71998244, Length=353, Percent_Identity=25.2124645892351, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI115534083, Length=441, Percent_Identity=21.0884353741497, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550877, Length=426, Percent_Identity=28.169014084507, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45551183, Length=426, Percent_Identity=28.169014084507, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24762620, Length=400, Percent_Identity=28.75, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24654186, Length=442, Percent_Identity=29.185520361991, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI17136952, Length=432, Percent_Identity=23.3796296296296, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI45551088, Length=397, Percent_Identity=25.9445843828715, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24652942, Length=397, Percent_Identity=25.9445843828715, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281364394, Length=381, Percent_Identity=24.9343832020997, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28574704, Length=381, Percent_Identity=24.9343832020997, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI17136950, Length=381, Percent_Identity=24.9343832020997, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28574702, Length=381, Percent_Identity=24.9343832020997, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI19921936, Length=383, Percent_Identity=26.8929503916449, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24661428, Length=497, Percent_Identity=26.3581488933602, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24639514, Length=301, Percent_Identity=27.906976744186, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24639516, Length=301, Percent_Identity=27.906976744186, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI221329674, Length=301, Percent_Identity=27.906976744186, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281365034, Length=394, Percent_Identity=25.8883248730964, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281364136, Length=520, Percent_Identity=25.5769230769231, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24655079, Length=300, Percent_Identity=28.6666666666667, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19921352, Length=393, Percent_Identity=25.1908396946565, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24584353, Length=393, Percent_Identity=25.1908396946565, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281363702, Length=399, Percent_Identity=24.812030075188, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363700, Length=304, Percent_Identity=26.9736842105263, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24582567, Length=450, Percent_Identity=22.4444444444444, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639853, Length=424, Percent_Identity=25.9433962264151, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24582569, Length=266, Percent_Identity=25.187969924812, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49379; Mature: 49247

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKSVERQSWSNRLAYVMTVAGATVGFGATWRFPYLVGENGGGAYVFLFCIAMIVIGIP
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHH
MILVENVIGRRIKVNAIDAFGGMANGKKIASGWKILGYMGLLGAFGILAYYMVLGGWVLN
HHHHHHHHCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YISSLISGTLDLSTPVTVETTASYYKESIQNSPMAIIGYTALFVLVNYFILSKGIVDGIE
HHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVKYLMPLLFVFLLVMVIRNVTLPGAAEGIAFYLMPDFSKITPKLFVFVLGQVFFALSL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
GFGVLITLSSYLDKNENLVKTATITGIMNTLIAVLAGFMIFPSLFSFGVAPNSGPTLVFQ
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEH
SLPIVFSNMWGGTLFAIIFFSLLVVAALTTSLTIYEVIITALQEKTKMSRKKAIAVTLST
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFVIGNIPSVLGDNLWQHIRIMDKSIFDAFDYISGNILFILTALGSAIFVGFVLKDEAKK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELGAGKVFTNIWFNYVKFVIPVIILVIFFNSL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANKSVERQSWSNRLAYVMTVAGATVGFGATWRFPYLVGENGGGAYVFLFCIAMIVIGIP
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHH
MILVENVIGRRIKVNAIDAFGGMANGKKIASGWKILGYMGLLGAFGILAYYMVLGGWVLN
HHHHHHHHCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YISSLISGTLDLSTPVTVETTASYYKESIQNSPMAIIGYTALFVLVNYFILSKGIVDGIE
HHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVKYLMPLLFVFLLVMVIRNVTLPGAAEGIAFYLMPDFSKITPKLFVFVLGQVFFALSL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
GFGVLITLSSYLDKNENLVKTATITGIMNTLIAVLAGFMIFPSLFSFGVAPNSGPTLVFQ
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEH
SLPIVFSNMWGGTLFAIIFFSLLVVAALTTSLTIYEVIITALQEKTKMSRKKAIAVTLST
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFVIGNIPSVLGDNLWQHIRIMDKSIFDAFDYISGNILFILTALGSAIFVGFVLKDEAKK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELGAGKVFTNIWFNYVKFVIPVIILVIFFNSL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]