Click here to switch to the map view.

The map label for this gene is murG

Identifier: 126207506

GI number: 126207506

Start: 20773

End: 21828

Strand: Direct

Name: murG

Synonym: APL_0018

Alternate gene names: 126207506

Gene position: 20773-21828 (Clockwise)

Preceding gene: 126207505

Following gene: 126207507

Centisome position: 0.91

GC content: 48.58

Gene sequence:

>1056_bases
ATGGCTAAAAAACTTCTTGTCATGGCAGGCGGAACCGGCGGTCATGTCTTTCCGGCAATTGCCGTAGCGCGCGAGTTGCA
AAAACAAGGCTGGGAGATCCGTTGGTTAGGTACCAAAGATCGAATGGAAGCCGACCTTGTGCCGAAGCACGGTATTCCGA
TTGAGTTTATTCAAATTTCCGGATTAAAAGGAAAGGGAATCGGTGCATTATTGAAAGCGCCGTTTGCGATTTTTAAAGCG
GTAATGCAAGCGCGTAAAATCATTAAAAATTACCAGCCTGATGCGGTACTCGGTATGGGCGGTTATGTGTCCGGACCGGG
CGGTATTGCTGCGAAATTGTGCGGTGTGCCGGTTATTTTACATGAACAAAATGCGGTTGCCGGTTTAACTAATGTCTGGT
TATCAAAAATCGCTCGCCGTGTGTTACAAGCGTTCCCGACCGCATTCCCAAATGCAGAAGTGGTGGGGAATCCGGTGCGT
GAAGATCTCGCCCAGCTCGAAGCGCCGGAAATTCGTTTTGCCGAACGCGGTTATCCGATCAATATTTTAGTAATGGGCGG
CAGCCAAGGCGCAAGAGTGATTAACCAAACCGTACCTGAAGTGGCGAAACAACTCGGTAACAATGTTTTTATTAGTCATC
AAGTAGGGAAAGGTAACCTCGGCGGGGTAGAAGAAATTTATCAAGCGACCGGCAACGGTATCGCCGCCGAATTTATTGAC
GATATGGCGCAGGCTTATAGTTGGGCGGACTTAGTGATTTGCCGTTCGGGAGCTTTAACCGTCTGCGAAATCGCCGCGGC
AGGCTTACCGGCAATTTTTGTGCCGTATCAACATAAAGATCGCCAACAATATTTGAATGCGACTTATTTGGCGGATGGCG
GTGCGGCAATCATTATCGAGCAACAAGATTTTACGCCGCAGACTTTATTGAATGTGTTACAACCGTTAATCGCCGATCGC
CGAAAACTCACCGAAATGGCGGTCAAAGCCAGAGCTAAAGCAACACCTACCGCAGCACAACGTGTGGCGGAAGTGATTAT
CGAACAAGCTAAATAG

Upstream 100 bases:

>100_bases
TTTCCGTAAATTGTCAATTTCCTGTACAATAACAACAATTTGTCTAAAAAAAGTTTCACAAGCGGTCGATTCCGCTCAAA
AGTTTGTAAAAGAGATCAAA

Downstream 100 bases:

>100_bases
TTTTAAATGCAATCAACAAAAATATTTGGTTGCACAGATAGGAAAACAACAATGAAAAATTTCCAAGATAAAATTAAAAA
ATTAGTGCCGGAAATGCGCC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MAKKLLVMAGGTGGHVFPAIAVARELQKQGWEIRWLGTKDRMEADLVPKHGIPIEFIQISGLKGKGIGALLKAPFAIFKA
VMQARKIIKNYQPDAVLGMGGYVSGPGGIAAKLCGVPVILHEQNAVAGLTNVWLSKIARRVLQAFPTAFPNAEVVGNPVR
EDLAQLEAPEIRFAERGYPINILVMGGSQGARVINQTVPEVAKQLGNNVFISHQVGKGNLGGVEEIYQATGNGIAAEFID
DMAQAYSWADLVICRSGALTVCEIAAAGLPAIFVPYQHKDRQQYLNATYLADGGAAIIIEQQDFTPQTLLNVLQPLIADR
RKLTEMAVKARAKATPTAAQRVAEVIIEQAK

Sequences:

>Translated_351_residues
MAKKLLVMAGGTGGHVFPAIAVARELQKQGWEIRWLGTKDRMEADLVPKHGIPIEFIQISGLKGKGIGALLKAPFAIFKA
VMQARKIIKNYQPDAVLGMGGYVSGPGGIAAKLCGVPVILHEQNAVAGLTNVWLSKIARRVLQAFPTAFPNAEVVGNPVR
EDLAQLEAPEIRFAERGYPINILVMGGSQGARVINQTVPEVAKQLGNNVFISHQVGKGNLGGVEEIYQATGNGIAAEFID
DMAQAYSWADLVICRSGALTVCEIAAAGLPAIFVPYQHKDRQQYLNATYLADGGAAIIIEQQDFTPQTLLNVLQPLIADR
RKLTEMAVKARAKATPTAAQRVAEVIIEQAK
>Mature_350_residues
AKKLLVMAGGTGGHVFPAIAVARELQKQGWEIRWLGTKDRMEADLVPKHGIPIEFIQISGLKGKGIGALLKAPFAIFKAV
MQARKIIKNYQPDAVLGMGGYVSGPGGIAAKLCGVPVILHEQNAVAGLTNVWLSKIARRVLQAFPTAFPNAEVVGNPVRE
DLAQLEAPEIRFAERGYPINILVMGGSQGARVINQTVPEVAKQLGNNVFISHQVGKGNLGGVEEIYQATGNGIAAEFIDD
MAQAYSWADLVICRSGALTVCEIAAAGLPAIFVPYQHKDRQQYLNATYLADGGAAIIIEQQDFTPQTLLNVLQPLIADRR
KLTEMAVKARAKATPTAAQRVAEVIIEQAK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=351, Percent_Identity=61.8233618233618, Blast_Score=433, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ACTP2 (A3MY90)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001052731.1
- ProteinModelPortal:   A3MY90
- SMR:   A3MY90
- STRING:   A3MY90
- GeneID:   4849438
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0018
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   A3MY90
- ProtClustDB:   PRK00726
- BioCyc:   APLE416269:APL_0018-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37647; Mature: 37516

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKLLVMAGGTGGHVFPAIAVARELQKQGWEIRWLGTKDRMEADLVPKHGIPIEFIQIS
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCCCCCEEEEEEE
GLKGKGIGALLKAPFAIFKAVMQARKIIKNYQPDAVLGMGGYVSGPGGIAAKLCGVPVIL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCHHHHHHHCCEEEE
HEQNAVAGLTNVWLSKIARRVLQAFPTAFPNAEVVGNPVREDLAQLEAPEIRFAERGYPI
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHCCCCCEEECCCCCCE
NILVMGGSQGARVINQTVPEVAKQLGNNVFISHQVGKGNLGGVEEIYQATGNGIAAEFID
EEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHH
DMAQAYSWADLVICRSGALTVCEIAAAGLPAIFVPYQHKDRQQYLNATYLADGGAAIIIE
HHHHHHHHHHHEEECCCCCHHHHHHHCCCCEEEECCCCCCHHHHHCEEEEECCCEEEEEE
QQDFTPQTLLNVLQPLIADRRKLTEMAVKARAKATPTAAQRVAEVIIEQAK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKKLLVMAGGTGGHVFPAIAVARELQKQGWEIRWLGTKDRMEADLVPKHGIPIEFIQIS
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCCCCCEEEEEEE
GLKGKGIGALLKAPFAIFKAVMQARKIIKNYQPDAVLGMGGYVSGPGGIAAKLCGVPVIL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCHHHHHHHCCEEEE
HEQNAVAGLTNVWLSKIARRVLQAFPTAFPNAEVVGNPVREDLAQLEAPEIRFAERGYPI
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHCCCCCEEECCCCCCE
NILVMGGSQGARVINQTVPEVAKQLGNNVFISHQVGKGNLGGVEEIYQATGNGIAAEFID
EEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHH
DMAQAYSWADLVICRSGALTVCEIAAAGLPAIFVPYQHKDRQQYLNATYLADGGAAIIIE
HHHHHHHHHHHEEECCCCCHHHHHHHCCCCEEEECCCCCCHHHHHCEEEEECCCEEEEEE
QQDFTPQTLLNVLQPLIADRRKLTEMAVKARAKATPTAAQRVAEVIIEQAK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA