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The map label for this gene is ftsW [H]

Identifier: 126207505

GI number: 126207505

Start: 19440

End: 20618

Strand: Direct

Name: ftsW [H]

Synonym: APL_0017

Alternate gene names: 126207505

Gene position: 19440-20618 (Clockwise)

Preceding gene: 126207504

Following gene: 126207506

Centisome position: 0.85

GC content: 44.02

Gene sequence:

>1179_bases
ATGTTAGAAAGATTGAAGACAGAATGGGATAAATGGGTTCGATTAACACCGGCGAATTCGTTATACGATCGTACTTTGCT
TTGGCTGTTTTTCGGCTTACTGGTTATCGGCTTCATTATGGTTACCTCGGCATCAATTCCGGTCAGTACCCGTTTAAACA
ATGATCCGTTTTATTTTGCGGTGCGTGACGGCGTCTATTTAGCGGCGGCATTGTTTGCCTTTGTCACGATCGTGCAAATT
CCGACCGAAAGCTGGGAAAAGCGAAACGTGCTGTTTTTCCTCGTATCGCTGGCTTTTTTGGTTATCGTATTGATTTTCGG
GCGCAGTATTAACGGTGCGGTACGTTGGATCCCGCTTGGTCCGGTCAATTTTCAGCCGGCGGAATTGGCAAAATTAGCGA
TCATTTGCTACTTTTCCAGTTTCTATGTGCGTAAATACGATGAAATGCGCACCAAACGGCTCAGTTTTATTCGTCCGATG
GTGATTCTCAGTATTTTCGGCTTTTTATTGCTGTTACAACCGGATTTAGGTAGTACCTTCGTACTCTTTATGCTCACTTT
TGCGATGTTGTTTATTATGGGCGCAAGAGTAATGCAGTTCCTATTTTTAGGGGTAACGGGTATTTTACTGTTCGCCTTTT
TGGTACTGACGTCAGAATATCGTTTAAAACGAGTAACCTCGTTTATGGATCCGTTCGCCGATGCTTACGGGGACGGTTTC
CAACTTTCAAATTCACAAATGGCATTCGGTCAGGGCGAATTTTGGGGACAGGGGTTAGGTAACTCAATCCAAAAATTAGA
ATACCTTCCCGAAGCGCATACCGACTTTGTTATGGCGGTAGTCGGTGAAGAATTCGGTTTTATCGGGATTGTCGCCATCG
TGATTTTATTATCGGTGTTATCGTTACGCGCACTTAAAATCAGTCGAGACGCATTAAAACTGGAAGCGCGTTTCAGAGGC
TTTTTCGCCTTCGGTATTGCGATTTGGATTTTTATTCAAGGCTTTGTGAACTTAGGCGTTGCCTCAGGTTTATTGCCAAC
CAAAGGTTTGACTTTCCCGCTGGTCAGTTACGGCGGATCCAGTTTAGTGATTATGTCGATCGCCATTGCGGTACTTTTAC
GCATAGACTATGAAAATCGCCTAGAACTGGTTGGACACGCTCAAATTAAAGAGAGTTAA

Upstream 100 bases:

>100_bases
GTGTTATTGTCACCGGCGTGCGCAAGTCTCGATCAATTTAAGAACTTTGAAGAACGCGGACAGGTTTTTGTTAAATTAGC
TCAGGAAGTAACCGCTTAAT

Downstream 100 bases:

>100_bases
GATCAACAAGCGGTCGGAATTTGCAAAAAATTTGCAAAAACTGACCGCTTTCTTTTTCCGTAAATTGTCAATTTCCTGTA
CAATAACAACAATTTGTCTA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MLERLKTEWDKWVRLTPANSLYDRTLLWLFFGLLVIGFIMVTSASIPVSTRLNNDPFYFAVRDGVYLAAALFAFVTIVQI
PTESWEKRNVLFFLVSLAFLVIVLIFGRSINGAVRWIPLGPVNFQPAELAKLAIICYFSSFYVRKYDEMRTKRLSFIRPM
VILSIFGFLLLLQPDLGSTFVLFMLTFAMLFIMGARVMQFLFLGVTGILLFAFLVLTSEYRLKRVTSFMDPFADAYGDGF
QLSNSQMAFGQGEFWGQGLGNSIQKLEYLPEAHTDFVMAVVGEEFGFIGIVAIVILLSVLSLRALKISRDALKLEARFRG
FFAFGIAIWIFIQGFVNLGVASGLLPTKGLTFPLVSYGGSSLVIMSIAIAVLLRIDYENRLELVGHAQIKES

Sequences:

>Translated_392_residues
MLERLKTEWDKWVRLTPANSLYDRTLLWLFFGLLVIGFIMVTSASIPVSTRLNNDPFYFAVRDGVYLAAALFAFVTIVQI
PTESWEKRNVLFFLVSLAFLVIVLIFGRSINGAVRWIPLGPVNFQPAELAKLAIICYFSSFYVRKYDEMRTKRLSFIRPM
VILSIFGFLLLLQPDLGSTFVLFMLTFAMLFIMGARVMQFLFLGVTGILLFAFLVLTSEYRLKRVTSFMDPFADAYGDGF
QLSNSQMAFGQGEFWGQGLGNSIQKLEYLPEAHTDFVMAVVGEEFGFIGIVAIVILLSVLSLRALKISRDALKLEARFRG
FFAFGIAIWIFIQGFVNLGVASGLLPTKGLTFPLVSYGGSSLVIMSIAIAVLLRIDYENRLELVGHAQIKES
>Mature_392_residues
MLERLKTEWDKWVRLTPANSLYDRTLLWLFFGLLVIGFIMVTSASIPVSTRLNNDPFYFAVRDGVYLAAALFAFVTIVQI
PTESWEKRNVLFFLVSLAFLVIVLIFGRSINGAVRWIPLGPVNFQPAELAKLAIICYFSSFYVRKYDEMRTKRLSFIRPM
VILSIFGFLLLLQPDLGSTFVLFMLTFAMLFIMGARVMQFLFLGVTGILLFAFLVLTSEYRLKRVTSFMDPFADAYGDGF
QLSNSQMAFGQGEFWGQGLGNSIQKLEYLPEAHTDFVMAVVGEEFGFIGIVAIVILLSVLSLRALKISRDALKLEARFRG
FFAFGIAIWIFIQGFVNLGVASGLLPTKGLTFPLVSYGGSSLVIMSIAIAVLLRIDYENRLELVGHAQIKES

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=362, Percent_Identity=53.8674033149171, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1786853, Length=321, Percent_Identity=32.7102803738318, Blast_Score=154, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44102; Mature: 44102

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERLKTEWDKWVRLTPANSLYDRTLLWLFFGLLVIGFIMVTSASIPVSTRLNNDPFYFA
CCCHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEE
VRDGVYLAAALFAFVTIVQIPTESWEKRNVLFFLVSLAFLVIVLIFGRSINGAVRWIPLG
EECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
PVNFQPAELAKLAIICYFSSFYVRKYDEMRTKRLSFIRPMVILSIFGFLLLLQPDLGSTF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VLFMLTFAMLFIMGARVMQFLFLGVTGILLFAFLVLTSEYRLKRVTSFMDPFADAYGDGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
QLSNSQMAFGQGEFWGQGLGNSIQKLEYLPEAHTDFVMAVVGEEFGFIGIVAIVILLSVL
EECCCCEECCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
SLRALKISRDALKLEARFRGFFAFGIAIWIFIQGFVNLGVASGLLPTKGLTFPLVSYGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCC
SLVIMSIAIAVLLRIDYENRLELVGHAQIKES
HHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MLERLKTEWDKWVRLTPANSLYDRTLLWLFFGLLVIGFIMVTSASIPVSTRLNNDPFYFA
CCCHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEE
VRDGVYLAAALFAFVTIVQIPTESWEKRNVLFFLVSLAFLVIVLIFGRSINGAVRWIPLG
EECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
PVNFQPAELAKLAIICYFSSFYVRKYDEMRTKRLSFIRPMVILSIFGFLLLLQPDLGSTF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VLFMLTFAMLFIMGARVMQFLFLGVTGILLFAFLVLTSEYRLKRVTSFMDPFADAYGDGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
QLSNSQMAFGQGEFWGQGLGNSIQKLEYLPEAHTDFVMAVVGEEFGFIGIVAIVILLSVL
EECCCCEECCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
SLRALKISRDALKLEARFRGFFAFGIAIWIFIQGFVNLGVASGLLPTKGLTFPLVSYGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCC
SLVIMSIAIAVLLRIDYENRLELVGHAQIKES
HHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]