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The map label for this gene is rsmC

Identifier: 126175727

GI number: 126175727

Start: 4150115

End: 4151158

Strand: Direct

Name: rsmC

Synonym: Sbal_3530

Alternate gene names: 126175727

Gene position: 4150115-4151158 (Clockwise)

Preceding gene: 126175726

Following gene: 126175728

Centisome position: 80.94

GC content: 50.1

Gene sequence:

>1044_bases
GTGTTAACCAATCCATCGCAAGTCATTATTCGTAATCAAGACAGCCTAAGCCAACATAAAGTGTTAGTGCTCAATCATGA
AGCCGATCTACTGCCAAAAGCCCTGCTCGATGTCGCGGCATCGGTCGATGCACTCGCCTTGGATTACCACCATTACTTGC
ACTTAGCGCCGCACGCCAACACAAAGCTGCGTTGCTATTTCGGCCATGACCTGCCGCACCAAGACCCGCTTGAACGAGAA
AAGTACGATACGGTTATTGTTTATTTCCCCAAAGCCAAACCCTTAGCACCTTATTTGTTTAACCTCGCCGCAAATCATCT
TGTGCCTAACGGCCAACTGTTAGTCGTGGGAGAAAACAAAGGCGGGATTAAGTCTTTAGTGAAGCTTTTGCCTGAGTATT
TTGCGACTGGGATGAAGCTCGATAACGCTCGCCACTGCCTGTTATTTGGCAGCAGTTTGGAAGGTAGCGCGCCGGCGATG
AAGCTCAGCGACTGGGTCAGTCAGTATCAACTGACTACACCACAGGGCGAGATCAGTATCTGCAACTTAGTTGGGGTGTT
TAGCGAAAAACGCTTAGATCTGGGCACTGAATTATTACTGTCGCACCTGCCGACACTCTCGGGCCGAGTGCTCGACTTTG
GTTGCGGCGCCGGCGTGATTGCCGCGGCCCTGCTCAAAGCCCAGCCGAGCTTATCCTTAGAGTGTGTCGATATTAATGCG
ATGGCCTTGGCTTCCTGCGAACTCACCTTAGCCGCCAATGGCATGACGGCCAAAGTCTATCCTTCAGATGGGCTCGCGCA
AACCACAGGGAAATTTAACGGCATTATCTCTAATCCGCCGTTCCACGATGGCCTTGCCAGCACCACCAGCATAGCGCAGA
ACTTTGTCACTGATAGCGCCAAGCAATTACAACATAATGGTATTTGGCAAATCGTCGCCAACCGCCACTTGCCCTATTCA
GATATCATTGCCGCCGAATTTGGCCAATTAAAAGTGGTTGCCGATAACAACAAGTACAAGCTGTATTACTTCCAACACAA
GTAA

Upstream 100 bases:

>100_bases
GGGATTTTATTAAGTCTTAGCGCAGGGATTCGATGCAAACTGGCTCAGGCGTGAATAACGGGTATAATGCCCACACTTAA
GTTTATAGGTGCCTGTAACT

Downstream 100 bases:

>100_bases
AACCGCTATCGAGAACGCGCTTATGCTTCAGCTATAGGCGCGTTATTGACTACGCCTCATACTCACTCGTATCACTATCC
CTGTTTTTTTCAGATAAAGC

Product: rRNA (guanine-N(2)-)-methyltransferase

Products: NA

Alternate protein names: 16S rRNA m2G1207 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rsmC

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLTNPSQVIIRNQDSLSQHKVLVLNHEADLLPKALLDVAASVDALALDYHHYLHLAPHANTKLRCYFGHDLPHQDPLERE
KYDTVIVYFPKAKPLAPYLFNLAANHLVPNGQLLVVGENKGGIKSLVKLLPEYFATGMKLDNARHCLLFGSSLEGSAPAM
KLSDWVSQYQLTTPQGEISICNLVGVFSEKRLDLGTELLLSHLPTLSGRVLDFGCGAGVIAAALLKAQPSLSLECVDINA
MALASCELTLAANGMTAKVYPSDGLAQTTGKFNGIISNPPFHDGLASTTSIAQNFVTDSAKQLQHNGIWQIVANRHLPYS
DIIAAEFGQLKVVADNNKYKLYYFQHK

Sequences:

>Translated_347_residues
MLTNPSQVIIRNQDSLSQHKVLVLNHEADLLPKALLDVAASVDALALDYHHYLHLAPHANTKLRCYFGHDLPHQDPLERE
KYDTVIVYFPKAKPLAPYLFNLAANHLVPNGQLLVVGENKGGIKSLVKLLPEYFATGMKLDNARHCLLFGSSLEGSAPAM
KLSDWVSQYQLTTPQGEISICNLVGVFSEKRLDLGTELLLSHLPTLSGRVLDFGCGAGVIAAALLKAQPSLSLECVDINA
MALASCELTLAANGMTAKVYPSDGLAQTTGKFNGIISNPPFHDGLASTTSIAQNFVTDSAKQLQHNGIWQIVANRHLPYS
DIIAAEFGQLKVVADNNKYKLYYFQHK
>Mature_347_residues
MLTNPSQVIIRNQDSLSQHKVLVLNHEADLLPKALLDVAASVDALALDYHHYLHLAPHANTKLRCYFGHDLPHQDPLERE
KYDTVIVYFPKAKPLAPYLFNLAANHLVPNGQLLVVGENKGGIKSLVKLLPEYFATGMKLDNARHCLLFGSSLEGSAPAM
KLSDWVSQYQLTTPQGEISICNLVGVFSEKRLDLGTELLLSHLPTLSGRVLDFGCGAGVIAAALLKAQPSLSLECVDINA
MALASCELTLAANGMTAKVYPSDGLAQTTGKFNGIISNPPFHDGLASTTSIAQNFVTDSAKQLQHNGIWQIVANRHLPYS
DIIAAEFGQLKVVADNNKYKLYYFQHK

Specific function: Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmC family

Homologues:

Organism=Escherichia coli, GI1790830, Length=344, Percent_Identity=36.3372093023256, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI87082206, Length=169, Percent_Identity=35.5029585798817, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMC_SHEB5 (A3D8E4)

Other databases:

- EMBL:   CP000563
- RefSeq:   YP_001051876.1
- ProteinModelPortal:   A3D8E4
- SMR:   A3D8E4
- STRING:   A3D8E4
- GeneID:   4844820
- GenomeReviews:   CP000563_GR
- KEGG:   sbl:Sbal_3530
- NMPDR:   fig|325240.3.peg.200
- eggNOG:   COG2813
- HOGENOM:   HBG296757
- OMA:   RHCQLWQ
- PhylomeDB:   A3D8E4
- ProtClustDB:   CLSK905955
- GO:   GO:0005737
- HAMAP:   MF_01862
- InterPro:   IPR002052
- InterPro:   IPR013675
- InterPro:   IPR007848

Pfam domain/function: PF05175 MTS; PF08468 MTS_N

EC number: =2.1.1.172

Molecular weight: Translated: 37879; Mature: 37879

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNPSQVIIRNQDSLSQHKVLVLNHEADLLPKALLDVAASVDALALDYHHYLHLAPHAN
CCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHEEEEEEHEEEECCCCC
TKLRCYFGHDLPHQDPLEREKYDTVIVYFPKAKPLAPYLFNLAANHLVPNGQLLVVGENK
CEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCC
GGIKSLVKLLPEYFATGMKLDNARHCLLFGSSLEGSAPAMKLSDWVSQYQLTTPQGEISI
CCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCCHHHHHHHHHEEEECCCCCEEE
CNLVGVFSEKRLDLGTELLLSHLPTLSGRVLDFGCGAGVIAAALLKAQPSLSLECVDINA
EEEEHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCE
MALASCELTLAANGMTAKVYPSDGLAQTTGKFNGIISNPPFHDGLASTTSIAQNFVTDSA
EEEEEEEEEEEECCEEEEEECCCCCHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHH
KQLQHNGIWQIVANRHLPYSDIIAAEFGQLKVVADNNKYKLYYFQHK
HHHHHCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCEEEEEEEECC
>Mature Secondary Structure
MLTNPSQVIIRNQDSLSQHKVLVLNHEADLLPKALLDVAASVDALALDYHHYLHLAPHAN
CCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHEEEEEEHEEEECCCCC
TKLRCYFGHDLPHQDPLEREKYDTVIVYFPKAKPLAPYLFNLAANHLVPNGQLLVVGENK
CEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCC
GGIKSLVKLLPEYFATGMKLDNARHCLLFGSSLEGSAPAMKLSDWVSQYQLTTPQGEISI
CCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCCHHHHHHHHHEEEECCCCCEEE
CNLVGVFSEKRLDLGTELLLSHLPTLSGRVLDFGCGAGVIAAALLKAQPSLSLECVDINA
EEEEHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCE
MALASCELTLAANGMTAKVYPSDGLAQTTGKFNGIISNPPFHDGLASTTSIAQNFVTDSA
EEEEEEEEEEEECCEEEEEECCCCCHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHH
KQLQHNGIWQIVANRHLPYSDIIAAEFGQLKVVADNNKYKLYYFQHK
HHHHHCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA