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The map label for this gene is ywbI [H]

Identifier: 126175587

GI number: 126175587

Start: 3970404

End: 3971294

Strand: Direct

Name: ywbI [H]

Synonym: Sbal_3390

Alternate gene names: 126175587

Gene position: 3970404-3971294 (Clockwise)

Preceding gene: 126175581

Following gene: 126175589

Centisome position: 77.44

GC content: 52.41

Gene sequence:

>891_bases
ATGGACCTCAAAGTTATTCGCTATTTTATCGAAATCGTCGATGCCGGAGGCTTTGGTAAAGCCAGCGAAAAAGTCCATCT
CACCCAACCTGCGTTATCAAAAGCCGTGCGCCAGTTAGAACAAGAACTCGATCTCACCTTGCTTGAGCGCGGTAAACGCG
GCACCCAAGTCAAACTCACTCCTGCAGGCGAAGTCGTTTATCGACACGGTAAAGACCTTCTCGCCGGAAGGCAACGCATG
CTAGCCGAACTCACGGCGCAGCGCAGCTTAACCGCAGGCGAACTCAATCTGGGATTAGCGCCGCTGGGCAGCGCCGAGAT
TTTTGCCCCCATTATTGCCAAGTATCGCCAGCAATATCCGCAAATAGACATGCACTTGCTCGTCCGTGGCGGTGTAGAAC
AAACTTCGGCGATCCAAAAGGGTGAGATTGAACTGGCCACAGGGATTATCGATTTTGATGATGGCTATGATGGTATTCGG
GTGTTTAACGATCCTATGGTAGTGGTGCTTCCCAAGGAAAATCCGTTATCCACCCGACAGATATTGTCGTTTAGCGATCT
CAGCGCCGATCCTCAAGTGATGTTCGAAACCGAATACACCCTCTACCAATTAGTGCTCAATGCCTGCCGACACGCCGGAT
TTGTCCCTAAAAACATCACCCGCGTTAGCCAAGCCGATTTCGGGATTGCCTTAGTCGCGGCGGGCACTGGGGTGATGGTA
TTGCCGCGCTCCATCGCGCGGCGCTACAGTGTACCCGGCGTCGTGAATATCCCGCTGGCGAGTGACGAGCTGCGCTGGGA
GCTATCGCTCTTTTGGCGCAAAGACCAAGTATTGTCCTTTGCAGCTCAAGCCATGATAGCTTTAGTCGAGAAGCACTTAA
CTCATAAGTGA

Upstream 100 bases:

>100_bases
TTTTCTATGGGGCTATTCTAGGCTTGCTTATTTGATAAAAAAAATGAATATTAAGAATGTAATACATGAATTTTAAGAAT
GTATTTAAAGGTGAAGCCCA

Downstream 100 bases:

>100_bases
CACTATGTTACCAAGGGATCACTAAGCTCAAACGCACTAGCGTATCGCTATCCCAAGGCAGAATAGGCAAATACTCAGCC
GAGTTAATATCGACTTTGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDLKVIRYFIEIVDAGGFGKASEKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLTPAGEVVYRHGKDLLAGRQRM
LAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYPQIDMHLLVRGGVEQTSAIQKGEIELATGIIDFDDGYDGIR
VFNDPMVVVLPKENPLSTRQILSFSDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK

Sequences:

>Translated_296_residues
MDLKVIRYFIEIVDAGGFGKASEKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLTPAGEVVYRHGKDLLAGRQRM
LAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYPQIDMHLLVRGGVEQTSAIQKGEIELATGIIDFDDGYDGIR
VFNDPMVVVLPKENPLSTRQILSFSDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK
>Mature_296_residues
MDLKVIRYFIEIVDAGGFGKASEKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLTPAGEVVYRHGKDLLAGRQRM
LAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYPQIDMHLLVRGGVEQTSAIQKGEIELATGIIDFDDGYDGIR
VFNDPMVVVLPKENPLSTRQILSFSDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=25, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI2367136, Length=260, Percent_Identity=25, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=26.962457337884, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=24.3986254295533, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788887, Length=302, Percent_Identity=27.4834437086093, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=22.4913494809689, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788297, Length=262, Percent_Identity=28.2442748091603, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787806, Length=290, Percent_Identity=28.9655172413793, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789506, Length=291, Percent_Identity=20.9621993127148, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787530, Length=245, Percent_Identity=23.6734693877551, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787601, Length=140, Percent_Identity=29.2857142857143, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790262, Length=256, Percent_Identity=21.484375, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=255, Percent_Identity=23.1372549019608, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081904, Length=177, Percent_Identity=25.4237288135593, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789204, Length=257, Percent_Identity=21.7898832684825, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786401, Length=119, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789440, Length=126, Percent_Identity=31.7460317460317, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32766; Mature: 32766

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKVIRYFIEIVDAGGFGKASEKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLT
CCHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEC
PAGEVVYRHGKDLLAGRQRMLAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYP
CCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QIDMHLLVRGGVEQTSAIQKGEIELATGIIDFDDGYDGIRVFNDPMVVVLPKENPLSTRQ
CCCEEEEEECCCCHHHHHCCCCEEEEEEEEECCCCCCCEEEECCCEEEEEECCCCCCHHH
ILSFSDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
HHHHHCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCEEE
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK
ECHHHHHHCCCCCEEECCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLKVIRYFIEIVDAGGFGKASEKVHLTQPALSKAVRQLEQELDLTLLERGKRGTQVKLT
CCHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEC
PAGEVVYRHGKDLLAGRQRMLAELTAQRSLTAGELNLGLAPLGSAEIFAPIIAKYRQQYP
CCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QIDMHLLVRGGVEQTSAIQKGEIELATGIIDFDDGYDGIRVFNDPMVVVLPKENPLSTRQ
CCCEEEEEECCCCHHHHHCCCCEEEEEEEEECCCCCCCEEEECCCEEEEEECCCCCCHHH
ILSFSDLSADPQVMFETEYTLYQLVLNACRHAGFVPKNITRVSQADFGIALVAAGTGVMV
HHHHHCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCEEE
LPRSIARRYSVPGVVNIPLASDELRWELSLFWRKDQVLSFAAQAMIALVEKHLTHK
ECHHHHHHCCCCCEEECCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]