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The map label for this gene is infC [H]

Identifier: 126174366

GI number: 126174366

Start: 2494591

End: 2495022

Strand: Direct

Name: infC [H]

Synonym: Sbal_2149

Alternate gene names: 126174366

Gene position: 2494591-2495022 (Clockwise)

Preceding gene: 126174365

Following gene: 126174367

Centisome position: 48.65

GC content: 44.21

Gene sequence:

>432_bases
GTGGTAAGCATCAGAGATGCTCAGAATTTGGCAGATGAAGCAGGTGTAGACCTGGTAGAAATCAGCCCAAATGCTGAACC
TCCAGTATGTCGCATTATGGACTACGGTAAGTTCCTTTTTGATAAGGCTAAGTCAGCCAAGGAACAAAAGAAGAAGCAAA
AGCAGGTTCAGGTTAAGGAAATTAAATTCCGTCCTGGAACTGACGAAAACGACTATCAGGTAAAACTACGCAACCTGATA
CGTTTTCTGGAAGACGGGGACAAAGCGAAGATTACGCTACGTTTCCGAGGTCGCGAAATGGCACACCAAAACCTGGGTAT
GGATCTATTGAACCGTATCAAGGCTGATTTGGACGAGTATGCGGTTGTTGAATCTTTTCCGAAAATGGAAGGCCGACAAG
CAATTATGGTGCTAGCGCCTAAAAAGAAATAA

Upstream 100 bases:

>100_bases
AAAAACAGCAGGGCGTCAGCCGGCCCCTAATAGAATCAATGAAGAAATCACAGGTGTACCTGAAGTACGCTTAACTGGCA
TTGATGGTGAAGCTATTGGT

Downstream 100 bases:

>100_bases
GTAGGGCAAAACTTAAAGTAGCAAAGGTCTATGGCCTTTGCTCGCCTTGCTTTTTATTAAACATCCCAATGCGGAGTTTT
AGAAATGCCTAAAATGAAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MVSIRDAQNLADEAGVDLVEISPNAEPPVCRIMDYGKFLFDKAKSAKEQKKKQKQVQVKEIKFRPGTDENDYQVKLRNLI
RFLEDGDKAKITLRFRGREMAHQNLGMDLLNRIKADLDEYAVVESFPKMEGRQAIMVLAPKKK

Sequences:

>Translated_143_residues
MVSIRDAQNLADEAGVDLVEISPNAEPPVCRIMDYGKFLFDKAKSAKEQKKKQKQVQVKEIKFRPGTDENDYQVKLRNLI
RFLEDGDKAKITLRFRGREMAHQNLGMDLLNRIKADLDEYAVVESFPKMEGRQAIMVLAPKKK
>Mature_143_residues
MVSIRDAQNLADEAGVDLVEISPNAEPPVCRIMDYGKFLFDKAKSAKEQKKKQKQVQVKEIKFRPGTDENDYQVKLRNLI
RFLEDGDKAKITLRFRGREMAHQNLGMDLLNRIKADLDEYAVVESFPKMEGRQAIMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=144, Percent_Identity=81.25, Blast_Score=216, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 16438; Mature: 16438

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRDAQNLADEAGVDLVEISPNAEPPVCRIMDYGKFLFDKAKSAKEQKKKQKQVQVKE
CCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKFRPGTDENDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQNLGMDLLNRIKADLDEY
EEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHH
AVVESFPKMEGRQAIMVLAPKKK
HHHHHCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MVSIRDAQNLADEAGVDLVEISPNAEPPVCRIMDYGKFLFDKAKSAKEQKKKQKQVQVKE
CCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKFRPGTDENDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQNLGMDLLNRIKADLDEY
EEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHH
AVVESFPKMEGRQAIMVLAPKKK
HHHHHCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA