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The map label for this gene is aroA [H]

Identifier: 126174289

GI number: 126174289

Start: 2400875

End: 2402155

Strand: Direct

Name: aroA [H]

Synonym: Sbal_2068

Alternate gene names: 126174289

Gene position: 2400875-2402155 (Clockwise)

Preceding gene: 126174285

Following gene: 126174290

Centisome position: 46.82

GC content: 48.63

Gene sequence:

>1281_bases
ATGAAGCAATTACGTCTTGAACCTGTTGTGCAAGTCCGCGGTGAGATCAATATTCCGGGCTCAAAAAGTATTTCAAATCG
TGCCTTATTATTGGCCACCTTAGCCCAAGGCACGACCACGCTTACCAATCTGCTCGACTCAGATGATATTCGCCACATGC
TGGCCTCCCTCAAGCAGTTAGGGGTGAACTATCGTTTATCTCAAAACAATACTGTGTGTGAACTTGATGGCTTAGGCGGT
GTGATTTCCTCAGAATCTGCGCAGGAATTGTTTTTAGGCAATGCGGGCACGGCAATGCGCCCCTTGTGCGCCGCCTTAAC
TCTTGGCCAAGGCGAATTTACCCTCACGGGCGAACCGCGTATGGAAGAGCGCCCGATTGGCGACTTAGTCGATGCCTTAA
GGCAACTCGGTGCCAATGTCGTTTATCTTAAAAATGACGGTTTCCCCCCGCTGACGATTAATGCGACGGGTCTTAGTGGC
GGCGATGTTGAAATTGCGGGCGATTTATCGAGCCAATTTTTAACAGCCCTATTGATGGTGGCGCCGCTTGCAAAGGGCAG
CGTAAATATCCATGTCAAAGGCGAGTTAGTTTCTAAGCCGTATATCGATATTACGTTGGCCCTGATGGCGCAATTTGGCG
TAACTGTCATCAACCATGACTATGCCCGTTTTGAGATTGTTGCAGGCCAGCGTTATGTATCACCGGGTAAAGTGCTGGTC
GAAGGTGATGCGTCATCGGCATCGTATTTCCTCGCCGCAGGGGCGATTAAGGGCGGTGAAGTCAAAGTCACCGGTGTGGG
CCGTTTAAGTATTCAAGGCGATGTGAAATTTGCCGATGTGCTTGAAAAAATGGGCGCTGATATTGAGTGGGGTGATGACT
ATATTATTGCCCGTGGCTCTCAATTAACGGCCGTTGATTTAGACATGAACCACATTCCCGATGCGGCTATGACCATTGCT
ACCGCAGCGTTATTTGCTAAAGGCACGACCGTTATTCGTAATATCTATAACTGGCGCATTAAAGAGACCGACCGCTTAGC
GGCCATGGCGACGGAATTACGTAAAGTAGGCGCTGAAGTGGAAGAGGGCAACGATTACATTAAAATCACCCCGCCTGCGG
TGATTAACACCGCAGAAATTGATACCTACAATGATCATCGTATGGCCATGTGTTTTTCGATGCTGGCATTTGCCGATTGC
GGTATTACTATCAATGATCCTGATTGCACTTCTAAAACATTCCCCGACTACTTTAAGCAGTTTGCGAGTCTGCAAGGCTA
A

Upstream 100 bases:

>100_bases
GTAATCTTAACTTGACGCTGTGTAGCGTGAAGTTGCCATTTTGCGTATTCAGTCCGCGTGATCGTGATGATGACGCCCTA
TAGAGAAAGAAGATTTATTC

Downstream 100 bases:

>100_bases
GTCCGTTTGTTTCGTTATTGTAACAACAAGCGATGTCAAGAATAGTCAGCCGTATTTGCGCGGCTGCTAATCTTCATAAA
AAATCCACGGATTTTGTTTG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKQLRLEPVVQVRGEINIPGSKSISNRALLLATLAQGTTTLTNLLDSDDIRHMLASLKQLGVNYRLSQNNTVCELDGLGG
VISSESAQELFLGNAGTAMRPLCAALTLGQGEFTLTGEPRMEERPIGDLVDALRQLGANVVYLKNDGFPPLTINATGLSG
GDVEIAGDLSSQFLTALLMVAPLAKGSVNIHVKGELVSKPYIDITLALMAQFGVTVINHDYARFEIVAGQRYVSPGKVLV
EGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGADIEWGDDYIIARGSQLTAVDLDMNHIPDAAMTIA
TAALFAKGTTVIRNIYNWRIKETDRLAAMATELRKVGAEVEEGNDYIKITPPAVINTAEIDTYNDHRMAMCFSMLAFADC
GITINDPDCTSKTFPDYFKQFASLQG

Sequences:

>Translated_426_residues
MKQLRLEPVVQVRGEINIPGSKSISNRALLLATLAQGTTTLTNLLDSDDIRHMLASLKQLGVNYRLSQNNTVCELDGLGG
VISSESAQELFLGNAGTAMRPLCAALTLGQGEFTLTGEPRMEERPIGDLVDALRQLGANVVYLKNDGFPPLTINATGLSG
GDVEIAGDLSSQFLTALLMVAPLAKGSVNIHVKGELVSKPYIDITLALMAQFGVTVINHDYARFEIVAGQRYVSPGKVLV
EGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGADIEWGDDYIIARGSQLTAVDLDMNHIPDAAMTIA
TAALFAKGTTVIRNIYNWRIKETDRLAAMATELRKVGAEVEEGNDYIKITPPAVINTAEIDTYNDHRMAMCFSMLAFADC
GITINDPDCTSKTFPDYFKQFASLQG
>Mature_426_residues
MKQLRLEPVVQVRGEINIPGSKSISNRALLLATLAQGTTTLTNLLDSDDIRHMLASLKQLGVNYRLSQNNTVCELDGLGG
VISSESAQELFLGNAGTAMRPLCAALTLGQGEFTLTGEPRMEERPIGDLVDALRQLGANVVYLKNDGFPPLTINATGLSG
GDVEIAGDLSSQFLTALLMVAPLAKGSVNIHVKGELVSKPYIDITLALMAQFGVTVINHDYARFEIVAGQRYVSPGKVLV
EGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGADIEWGDDYIIARGSQLTAVDLDMNHIPDAAMTIA
TAALFAKGTTVIRNIYNWRIKETDRLAAMATELRKVGAEVEEGNDYIKITPPAVINTAEIDTYNDHRMAMCFSMLAFADC
GITINDPDCTSKTFPDYFKQFASLQG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=424, Percent_Identity=67.688679245283, Blast_Score=577, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6320332, Length=451, Percent_Identity=36.8070953436807, Blast_Score=242, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45701; Mature: 45701

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLRLEPVVQVRGEINIPGSKSISNRALLLATLAQGTTTLTNLLDSDDIRHMLASLKQL
CCCCCCCCCEEECCEEECCCCCCCCCCEEEEEEHHCCHHHHHHHHCCHHHHHHHHHHHHC
GVNYRLSQNNTVCELDGLGGVISSESAQELFLGNAGTAMRPLCAALTLGQGEFTLTGEPR
CCEEEECCCCCEEEECCCCCCCCCCCCHHHEECCCCCHHHHHHHHHEECCCCEEECCCCC
MEERPIGDLVDALRQLGANVVYLKNDGFPPLTINATGLSGGDVEIAGDLSSQFLTALLMV
CCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHH
APLAKGSVNIHVKGELVSKPYIDITLALMAQFGVTVINHDYARFEIVAGQRYVSPGKVLV
HHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEECCCEEEEEEECCEECCCCCEEE
EGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGADIEWGDDYIIARGS
ECCCCCCEEEEEECCCCCCEEEEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCEEEECCC
QLTAVDLDMNHIPDAAMTIATAALFAKGTTVIRNIYNWRIKETDRLAAMATELRKVGAEV
EEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCEECCHHHHHHHHHHHHHHCCCH
EEGNDYIKITPPAVINTAEIDTYNDHRMAMCFSMLAFADCGITINDPDCTSKTFPDYFKQ
HCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHH
FASLQG
HHCCCC
>Mature Secondary Structure
MKQLRLEPVVQVRGEINIPGSKSISNRALLLATLAQGTTTLTNLLDSDDIRHMLASLKQL
CCCCCCCCCEEECCEEECCCCCCCCCCEEEEEEHHCCHHHHHHHHCCHHHHHHHHHHHHC
GVNYRLSQNNTVCELDGLGGVISSESAQELFLGNAGTAMRPLCAALTLGQGEFTLTGEPR
CCEEEECCCCCEEEECCCCCCCCCCCCHHHEECCCCCHHHHHHHHHEECCCCEEECCCCC
MEERPIGDLVDALRQLGANVVYLKNDGFPPLTINATGLSGGDVEIAGDLSSQFLTALLMV
CCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHH
APLAKGSVNIHVKGELVSKPYIDITLALMAQFGVTVINHDYARFEIVAGQRYVSPGKVLV
HHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCEEEECCCEEEEEEECCEECCCCCEEE
EGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGADIEWGDDYIIARGS
ECCCCCCEEEEEECCCCCCEEEEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCEEEECCC
QLTAVDLDMNHIPDAAMTIATAALFAKGTTVIRNIYNWRIKETDRLAAMATELRKVGAEV
EEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCEECCHHHHHHHHHHHHHHCCCH
EEGNDYIKITPPAVINTAEIDTYNDHRMAMCFSMLAFADCGITINDPDCTSKTFPDYFKQ
HCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHH
FASLQG
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA