Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 126174285

GI number: 126174285

Start: 2395531

End: 2396451

Strand: Direct

Name: nahR [H]

Synonym: Sbal_2064

Alternate gene names: 126174285

Gene position: 2395531-2396451 (Clockwise)

Preceding gene: 126174284

Following gene: 126174289

Centisome position: 46.72

GC content: 46.15

Gene sequence:

>921_bases
ATGGATTTGGCCAAGCTTTCGCGCATTAGTATGAAGCATTTGATCACTTTACATGTGATGCTCGATACTCTGAGCGTAAC
CGCCAGCGCCGAACGTTTATGTCTTAGCCCCTCATCCGTCAGTAAAACCTTAAGCCAGCTCAGGGACAGTTTGAACGATG
AACTGTTCTATCGTAATGGCAACTCACTGGTCGCAACCCCATTGGCAAGACGATTAGGCCCAAGCGTGCAGCAAATGATC
AATGATATGAATCAGATCATGAGTCAAGATGCGTTTAATCCAGCACATTTTGAGGGGCGTTTTTCACTTGCGATGCGCGA
AAGTACCTTTGAACTGCTGGTCGCCAAATTAAGTGCCCATATTCTCAGTTTGGCCCCACATATCCATCTCGATATTTATA
GCAAAGACAATATTGGTTTTGATGGACTCATCAAAGGCTCGTTAGATTTTGTGCTGTTACCTCACGATCTGAGCCAACCT
AATTATCTTCAAGACGATCTGGTGTGGGAAACCTTGTTCAGCGATGAAATGGTCTGTCTGATGAATTCGTCCCATCCCTT
GGCTAAACAGCCGCAGATCAGCTTCGATGATTACCTAAGTTACCGCCATATTGGCATTACCGATACGGATCTGAGTACGC
CATTTTTTGATATTTTGCTCGCCCAGCAATCTAAAAAACGTGCTGTCCCCATTTCGGTCCCTGATTTTGGCAGCGCGGCG
TTAATGTGCCACCACAGTGAATTGCTTTTTACTTGTTCGCGCCGCTGGGCATCCATAGCCAGCCAGGCTAAAGGATTAAC
CGTTAAATCCTTACCGATAGAATATGGCAAAGTGGCTTACAGTCTCGTTTGGCATCGACAAAGCATGAAGGATCCCGCGC
TGCGCTGGCTTTACGAGCAAATTTTGCTTTGCAGTCGTTAA

Upstream 100 bases:

>100_bases
ATTCTCAGCAATATGTTTGGTTGGTTGCATGCTATTGTTTATCATGCTTAAAAGTACGCGTTTGAGTGTGCATAGAAGAT
AAACCAATAGGATGTCACAG

Downstream 100 bases:

>100_bases
ATATAGCAAGAGGGCAAGATAAGATTTGTAACGCCTCGCTTTGCAAGCTTTGCGGCCAAGCGTTCAATATCGGTTTGTGT
GCAGCTTGGCCACGTTAACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRDSLNDELFYRNGNSLVATPLARRLGPSVQQMI
NDMNQIMSQDAFNPAHFEGRFSLAMRESTFELLVAKLSAHILSLAPHIHLDIYSKDNIGFDGLIKGSLDFVLLPHDLSQP
NYLQDDLVWETLFSDEMVCLMNSSHPLAKQPQISFDDYLSYRHIGITDTDLSTPFFDILLAQQSKKRAVPISVPDFGSAA
LMCHHSELLFTCSRRWASIASQAKGLTVKSLPIEYGKVAYSLVWHRQSMKDPALRWLYEQILLCSR

Sequences:

>Translated_306_residues
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRDSLNDELFYRNGNSLVATPLARRLGPSVQQMI
NDMNQIMSQDAFNPAHFEGRFSLAMRESTFELLVAKLSAHILSLAPHIHLDIYSKDNIGFDGLIKGSLDFVLLPHDLSQP
NYLQDDLVWETLFSDEMVCLMNSSHPLAKQPQISFDDYLSYRHIGITDTDLSTPFFDILLAQQSKKRAVPISVPDFGSAA
LMCHHSELLFTCSRRWASIASQAKGLTVKSLPIEYGKVAYSLVWHRQSMKDPALRWLYEQILLCSR
>Mature_306_residues
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRDSLNDELFYRNGNSLVATPLARRLGPSVQQMI
NDMNQIMSQDAFNPAHFEGRFSLAMRESTFELLVAKLSAHILSLAPHIHLDIYSKDNIGFDGLIKGSLDFVLLPHDLSQP
NYLQDDLVWETLFSDEMVCLMNSSHPLAKQPQISFDDYLSYRHIGITDTDLSTPFFDILLAQQSKKRAVPISVPDFGSAA
LMCHHSELLFTCSRRWASIASQAKGLTVKSLPIEYGKVAYSLVWHRQSMKDPALRWLYEQILLCSR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=293, Percent_Identity=25.5972696245734, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=24.4299674267101, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34499; Mature: 34499

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50931 HTH_LYSR ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRDSLNDELFYRNG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEECC
NSLVATPLARRLGPSVQQMINDMNQIMSQDAFNPAHFEGRFSLAMRESTFELLVAKLSAH
CCEEECHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
ILSLAPHIHLDIYSKDNIGFDGLIKGSLDFVLLPHDLSQPNYLQDDLVWETLFSDEMVCL
HHHHCCEEEEEEEECCCCCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEEE
MNSSHPLAKQPQISFDDYLSYRHIGITDTDLSTPFFDILLAQQSKKRAVPISVPDFGSAA
ECCCCCCCCCCCCCHHHHHCEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEE
LMCHHSELLFTCSRRWASIASQAKGLTVKSLPIEYGKVAYSLVWHRQSMKDPALRWLYEQ
EEEECHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILLCSR
HHHCCC
>Mature Secondary Structure
MDLAKLSRISMKHLITLHVMLDTLSVTASAERLCLSPSSVSKTLSQLRDSLNDELFYRNG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEECC
NSLVATPLARRLGPSVQQMINDMNQIMSQDAFNPAHFEGRFSLAMRESTFELLVAKLSAH
CCEEECHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
ILSLAPHIHLDIYSKDNIGFDGLIKGSLDFVLLPHDLSQPNYLQDDLVWETLFSDEMVCL
HHHHCCEEEEEEEECCCCCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEEE
MNSSHPLAKQPQISFDDYLSYRHIGITDTDLSTPFFDILLAQQSKKRAVPISVPDFGSAA
ECCCCCCCCCCCCCHHHHHCEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEE
LMCHHSELLFTCSRRWASIASQAKGLTVKSLPIEYGKVAYSLVWHRQSMKDPALRWLYEQ
EEEECHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILLCSR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]