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The map label for this gene is map [H]

Identifier: 126173687

GI number: 126173687

Start: 1681803

End: 1682609

Strand: Reverse

Name: map [H]

Synonym: Sbal_1449

Alternate gene names: 126173687

Gene position: 1682609-1681803 (Counterclockwise)

Preceding gene: 126173705

Following gene: 126173686

Centisome position: 32.82

GC content: 46.47

Gene sequence:

>807_bases
ATGAGTATAGTCATCAAGACAGCTGAAGAAATTGAAAAAATGCGTGCTGCGGGCAAACTTGCCGCACAGGTATTAGAAAT
GATCGCTCCGCACGTTAAGCCGGGCGTGACCACCAATGAACTCAATGACCTCTGCGCCAAATATACCGAAGAGCAAGGTG
CGATTTCGGCGCCGCTTAACTATCATGGTTTTCCTAAGTCCATTTGTACTTCTGTAAACCATGTGATTTGCCACGGTATT
CCAAACGACAACCCACCATTGAAAGAAGGCGATATCCTCAATATCGACATCACAGTGATTAAAGACGGCTATCACGGCGA
TACCTCACAGATGTTTTTGATTGGTGAAGTGAGCGCGAAGGATAAACGTCTGTGCCGCATCGCACAAGAAAGCCTGTATT
TGGCCATTCGTAAGGTGCGTCCAGGCCTAAAACTGGGTGAAATTGGCAATACTATCGAAAAATTCATCAAAGCAAGCAAA
ACAGGCCTTGAGAAATATTCCATCGTGCAAGATTATTGTGGCCACGGTATTGGCTCTGGTTTCCATGAGGAACCTCAGGT
CATGCATTACCGCAACGGCGATAACACAGTATTACGCCCAGGCATGTGTTTCACTATTGAACCTATGATCAATGCCGGTC
GCCACACGACCATACTCGATCGCGATGATAAGTGGACGGTTACCACCTCCGATGGTAAAAATTCTGCCCAGTGGGAACAT
ACCCTACTTGTGACTGAAAAAGGGGTTGAAGTACTGACCCTACGTGAGGATGAAGATTTTCCACGCATCATCAATCACGA
TCGATAG

Upstream 100 bases:

>100_bases
AAACATAACGGCGCGCTTTATACCATAAATAGCCCTAAAGCACAAATTTTTGCATTAGGTTGCGTGGCCAACAGACATTA
AAGACACAAGAGAAAACGCA

Downstream 100 bases:

>100_bases
GCCAAACCAACAAAAATAAAAACAAGGGACTCGATGAATATAGCTCTGCTCGCTAAACAATCATTAATCGAACAGAATCA
GACTCTTTTAGCCAGTTTCA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKPGVTTNELNDLCAKYTEEQGAISAPLNYHGFPKSICTSVNHVICHGI
PNDNPPLKEGDILNIDITVIKDGYHGDTSQMFLIGEVSAKDKRLCRIAQESLYLAIRKVRPGLKLGEIGNTIEKFIKASK
TGLEKYSIVQDYCGHGIGSGFHEEPQVMHYRNGDNTVLRPGMCFTIEPMINAGRHTTILDRDDKWTVTTSDGKNSAQWEH
TLLVTEKGVEVLTLREDEDFPRIINHDR

Sequences:

>Translated_268_residues
MSIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKPGVTTNELNDLCAKYTEEQGAISAPLNYHGFPKSICTSVNHVICHGI
PNDNPPLKEGDILNIDITVIKDGYHGDTSQMFLIGEVSAKDKRLCRIAQESLYLAIRKVRPGLKLGEIGNTIEKFIKASK
TGLEKYSIVQDYCGHGIGSGFHEEPQVMHYRNGDNTVLRPGMCFTIEPMINAGRHTTILDRDDKWTVTTSDGKNSAQWEH
TLLVTEKGVEVLTLREDEDFPRIINHDR
>Mature_267_residues
SIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKPGVTTNELNDLCAKYTEEQGAISAPLNYHGFPKSICTSVNHVICHGIP
NDNPPLKEGDILNIDITVIKDGYHGDTSQMFLIGEVSAKDKRLCRIAQESLYLAIRKVRPGLKLGEIGNTIEKFIKASKT
GLEKYSIVQDYCGHGIGSGFHEEPQVMHYRNGDNTVLRPGMCFTIEPMINAGRHTTILDRDDKWTVTTSDGKNSAQWEHT
LLVTEKGVEVLTLREDEDFPRIINHDR

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=265, Percent_Identity=45.6603773584906, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=41.6666666666667, Blast_Score=199, Evalue=3e-51,
Organism=Escherichia coli, GI1786364, Length=269, Percent_Identity=60.2230483271376, Blast_Score=337, Evalue=6e-94,
Organism=Escherichia coli, GI1788728, Length=257, Percent_Identity=27.2373540856031, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71996291, Length=256, Percent_Identity=45.3125, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6323273, Length=256, Percent_Identity=47.65625, Blast_Score=232, Evalue=4e-62,
Organism=Drosophila melanogaster, GI21355531, Length=252, Percent_Identity=48.4126984126984, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=40.5622489959839, Blast_Score=195, Evalue=3e-50,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29835; Mature: 29704

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKPGVTTNELNDLCAKYTEEQGAISAPLN
CEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCC
YHGFPKSICTSVNHVICHGIPNDNPPLKEGDILNIDITVIKDGYHGDTSQMFLIGEVSAK
CCCCCHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCC
DKRLCRIAQESLYLAIRKVRPGLKLGEIGNTIEKFIKASKTGLEKYSIVQDYCGHGIGSG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
FHEEPQVMHYRNGDNTVLRPGMCFTIEPMINAGRHTTILDRDDKWTVTTSDGKNSAQWEH
CCCCCCEEEEECCCCCEECCCCEEEECHHHCCCCCEEEEECCCCEEEEECCCCCCCCEEE
TLLVTEKGVEVLTLREDEDFPRIINHDR
EEEEEECCCEEEEEECCCCCCHHCCCCC
>Mature Secondary Structure 
SIVIKTAEEIEKMRAAGKLAAQVLEMIAPHVKPGVTTNELNDLCAKYTEEQGAISAPLN
EEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCC
YHGFPKSICTSVNHVICHGIPNDNPPLKEGDILNIDITVIKDGYHGDTSQMFLIGEVSAK
CCCCCHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCC
DKRLCRIAQESLYLAIRKVRPGLKLGEIGNTIEKFIKASKTGLEKYSIVQDYCGHGIGSG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
FHEEPQVMHYRNGDNTVLRPGMCFTIEPMINAGRHTTILDRDDKWTVTTSDGKNSAQWEH
CCCCCCEEEEECCCCCEECCCCEEEECHHHCCCCCEEEEECCCCEEEEECCCCCCCCEEE
TLLVTEKGVEVLTLREDEDFPRIINHDR
EEEEEECCCEEEEEECCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]