BacMap

Definition	Methylibium petroleiphilum PM1 chromosome, complete genome.
Accession	NC_008825
Length	4,044,195

Click here to switch to the map view.

The map label for this gene is fadB1 [H]

Identifier: 124265790

GI number: 124265790

Start: 627910

End: 628698

Strand: Direct

Name: fadB1 [H]

Synonym: Mpe_A0597

Alternate gene names: 124265790

Gene position: 627910-628698 (Clockwise)

Preceding gene: 124265788

Following gene: 124265794

Centisome position: 15.53

GC content: 69.33

Gene sequence:

>789_bases
ATGGACTACCAGCATCTGCTGACCGAAGTGCGCGGCAGCGCCGCGCTGAAGACCGGGTGGATCACTCTGAACCGGCCCAA
GGCGCTGAATGCGCTCAACGATGCGCTGATGGACGAACTGGGCGACGCGCTGCGGGTCTACGATGCCGACGCCTCGATCG
GCTGCGTGGTGATCACCGGCAGCGAGAAGGCCTTCGCCGCCGGCGCCGACATCGGCGGCATGGCGTCGCAGACCTACATG
GACGCCTACAAGGGCGACTTCATCACCCGCAACTGGGAGGCGGTGCGCAGCGTGCGCAAGCCGGTGATCGCGGCAGTGGC
CGGCTACGCGCTGGGCGGTGGCTGCGAGCTGGCCATGATGTGCGACCTGATCATCGCCGCGGACACGGCGCGCTTCGGTC
AGCCGGAGATCAAGCTCGGCATCATCCCCGGCGCTGGCGGCACGCAGCGGCTGCCGCGGGCGGTCGGCAAGGCCAAGGCG
ATGGACCTGGTGCTGACGGCACGCATGATGGATGCGGCCGAGGCCGAGCGCGCCGGCCTGGTGTCACGCGTGGTGCCGGC
CGATCGCCTGCTGGCCGAGGCCCAGGAGGCGGCGGACGCGATCGGCGCGATGGGGTTGCCGGCCATCCTGGTGGCCAAGG
AGTGCGTGAACCGCGCCTACGAGTCGCCGCTGTCGGACGGCGTGTGGTTCGAGCGGCGCATGTTCCAGTCGCTGTTCGGC
ACCGAGGACCAGAAGGAAGGCATGGACGCCTTCGCGAACAAGCGCAAGCCGGTGTTCCGTCACCGCTGA

Upstream 100 bases:

>100_bases
TCCCCGGCTGCGTCACCCGGTCGGCTGCGCAGCAGCAGGTGCGAAGGACAGCACGCCGCTGCCCGTTACAGTGTCACCTA
CTGCGAAAGGACGCCCTGAC

Downstream 100 bases:

>100_bases
GCGGCAGCGCGCTCGTCCTCCAGGATCTGCGCGAACTCCTCGTCGGTGAACAGCCTCGACCGGGTGTGGAAGGCCTTGCC
TTCCGGCCCCTCGAGCGAGA

Product: short chain enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MDYQHLLTEVRGSAALKTGWITLNRPKALNALNDALMDELGDALRVYDADASIGCVVITGSEKAFAAGADIGGMASQTYM
DAYKGDFITRNWEAVRSVRKPVIAAVAGYALGGGCELAMMCDLIIAADTARFGQPEIKLGIIPGAGGTQRLPRAVGKAKA
MDLVLTARMMDAAEAERAGLVSRVVPADRLLAEAQEAADAIGAMGLPAILVAKECVNRAYESPLSDGVWFERRMFQSLFG
TEDQKEGMDAFANKRKPVFRHR

Sequences:

>Translated_262_residues
MDYQHLLTEVRGSAALKTGWITLNRPKALNALNDALMDELGDALRVYDADASIGCVVITGSEKAFAAGADIGGMASQTYM
DAYKGDFITRNWEAVRSVRKPVIAAVAGYALGGGCELAMMCDLIIAADTARFGQPEIKLGIIPGAGGTQRLPRAVGKAKA
MDLVLTARMMDAAEAERAGLVSRVVPADRLLAEAQEAADAIGAMGLPAILVAKECVNRAYESPLSDGVWFERRMFQSLFG
TEDQKEGMDAFANKRKPVFRHR
>Mature_262_residues
MDYQHLLTEVRGSAALKTGWITLNRPKALNALNDALMDELGDALRVYDADASIGCVVITGSEKAFAAGADIGGMASQTYM
DAYKGDFITRNWEAVRSVRKPVIAAVAGYALGGGCELAMMCDLIIAADTARFGQPEIKLGIIPGAGGTQRLPRAVGKAKA
MDLVLTARMMDAAEAERAGLVSRVVPADRLLAEAQEAADAIGAMGLPAILVAKECVNRAYESPLSDGVWFERRMFQSLFG
TEDQKEGMDAFANKRKPVFRHR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=261, Percent_Identity=49.8084291187739, Blast_Score=266, Evalue=1e-71,
Organism=Homo sapiens, GI4502327, Length=268, Percent_Identity=34.3283582089552, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI68989263, Length=182, Percent_Identity=36.8131868131868, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI31542718, Length=244, Percent_Identity=28.6885245901639, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI70995211, Length=196, Percent_Identity=36.734693877551, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI20127408, Length=209, Percent_Identity=33.0143540669856, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI150378541, Length=244, Percent_Identity=31.1475409836066, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI37594471, Length=194, Percent_Identity=30.9278350515464, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI37594469, Length=194, Percent_Identity=30.9278350515464, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI213417737, Length=231, Percent_Identity=29.4372294372294, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI157694516, Length=231, Percent_Identity=29.4372294372294, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI260274832, Length=211, Percent_Identity=28.436018957346, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI45643119, Length=211, Percent_Identity=28.436018957346, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI260275230, Length=211, Percent_Identity=28.436018957346, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI261878539, Length=93, Percent_Identity=43.010752688172, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4757968, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI49355787, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI25453481, Length=201, Percent_Identity=28.3582089552239, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI51538573, Length=201, Percent_Identity=28.3582089552239, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4757966, Length=201, Percent_Identity=28.3582089552239, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI51538581, Length=201, Percent_Identity=28.3582089552239, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI157694520, Length=194, Percent_Identity=30.4123711340206, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI221307494, Length=162, Percent_Identity=31.4814814814815, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI221136756, Length=162, Percent_Identity=31.4814814814815, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI221136753, Length=162, Percent_Identity=31.4814814814815, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1787659, Length=242, Percent_Identity=46.2809917355372, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI221142681, Length=247, Percent_Identity=39.2712550607287, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788597, Length=249, Percent_Identity=33.7349397590361, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787660, Length=247, Percent_Identity=34.8178137651822, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082183, Length=269, Percent_Identity=32.7137546468402, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790281, Length=179, Percent_Identity=32.9608938547486, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788682, Length=186, Percent_Identity=32.7956989247312, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=242, Percent_Identity=55.3719008264463, Blast_Score=270, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=48.8095238095238, Blast_Score=238, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17540714, Length=217, Percent_Identity=32.7188940092166, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17540306, Length=239, Percent_Identity=31.7991631799163, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17560910, Length=243, Percent_Identity=28.8065843621399, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17534483, Length=256, Percent_Identity=26.953125, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17558304, Length=162, Percent_Identity=35.8024691358025, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=210, Percent_Identity=31.9047619047619, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25144276, Length=164, Percent_Identity=37.8048780487805, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17508953, Length=164, Percent_Identity=37.8048780487805, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17508951, Length=164, Percent_Identity=37.8048780487805, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144160, Length=197, Percent_Identity=29.4416243654822, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25144157, Length=197, Percent_Identity=29.4416243654822, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=212, Percent_Identity=28.7735849056604, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=257, Percent_Identity=28.4046692607004, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25141363, Length=216, Percent_Identity=24.537037037037, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=182, Percent_Identity=29.6703296703297, Blast_Score=85, Evalue=9e-18,
Organism=Drosophila melanogaster, GI20129971, Length=260, Percent_Identity=55.3846153846154, Blast_Score=286, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24653477, Length=260, Percent_Identity=55.3846153846154, Blast_Score=286, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24653139, Length=270, Percent_Identity=35.9259259259259, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI21357171, Length=249, Percent_Identity=30.1204819277108, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19922422, Length=242, Percent_Identity=27.6859504132231, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24650670, Length=240, Percent_Identity=30, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24654903, Length=194, Percent_Identity=29.3814432989691, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19920382, Length=255, Percent_Identity=28.2352941176471, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28571729, Length=187, Percent_Identity=28.8770053475936, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571730, Length=187, Percent_Identity=28.8770053475936, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921000, Length=191, Percent_Identity=33.5078534031414, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583077, Length=191, Percent_Identity=33.5078534031414, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583079, Length=191, Percent_Identity=33.5078534031414, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28072; Mature: 28072

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYQHLLTEVRGSAALKTGWITLNRPKALNALNDALMDELGDALRVYDADASIGCVVITG
CCHHHHHHHHCCCHHEEECCEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEC
SEKAFAAGADIGGMASQTYMDAYKGDFITRNWEAVRSVRKPVIAAVAGYALGGGCELAMM
CCCCEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
CDLIIAADTARFGQPEIKLGIIPGAGGTQRLPRAVGKAKAMDLVLTARMMDAAEAERAGL
HHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRVVPADRLLAEAQEAADAIGAMGLPAILVAKECVNRAYESPLSDGVWFERRMFQSLFG
HHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
TEDQKEGMDAFANKRKPVFRHR
CCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDYQHLLTEVRGSAALKTGWITLNRPKALNALNDALMDELGDALRVYDADASIGCVVITG
CCHHHHHHHHCCCHHEEECCEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEC
SEKAFAAGADIGGMASQTYMDAYKGDFITRNWEAVRSVRKPVIAAVAGYALGGGCELAMM
CCCCEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
CDLIIAADTARFGQPEIKLGIIPGAGGTQRLPRAVGKAKAMDLVLTARMMDAAEAERAGL
HHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRVVPADRLLAEAQEAADAIGAMGLPAILVAKECVNRAYESPLSDGVWFERRMFQSLFG
HHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
TEDQKEGMDAFANKRKPVFRHR
CCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]