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The map label for this gene is fliM [H]

Identifier: 124265765

GI number: 124265765

Start: 604501

End: 605502

Strand: Direct

Name: fliM [H]

Synonym: Mpe_A0572

Alternate gene names: 124265765

Gene position: 604501-605502 (Clockwise)

Preceding gene: 124265764

Following gene: 124265766

Centisome position: 14.95

GC content: 65.37

Gene sequence:

>1002_bases
ATGAATCAGCAGATCCTGTCGCAGGACGAGGTGGATGCGCTGTTGCAGGGCATCACCGGCGAGAGCCAGAAGCTCGAGAC
CGAGGAGGTCGAGCAGGGCGGCGTGCGCGACTACAACCTGGCGAGCCAGGAGCGCATCGTGCGAGGGCGCATGCCCACGA
TGGAGATCATCAACGAGCGCTTCTCCCGCAACATCCGCATCGGCCTGTTCAATTTCATCCGGCGCACGCCGGAGGTGGCG
GTCGGCACGATCAAGGTGCAGAAGTACAGCGCCTTCCTGCGCGAGATCGTGGTGCCGACCAACTTCAACATCATGGCGGT
GCGACCGCTGCGCGGCAGCGGGCTGATCGTCTGCGATCCGACGCTGGTGTTCGCGGTGATCGACGCGCTGTTCGGCGGGG
CCGGCAAGTTCCACACCCGCATCGAGGGGCGTGATTTTTCGCCGACCGAGCTGCGCGTGATCTCGCGCCTGGTCGAGGTG
ATCTCGGCCGAGTACAAGAAGGCCTGGGCCGGTGTCTACCCGGTCGAGCTGGAGTACCAGCGTTCGGAGATGCAGCCGCA
GTTCGCGACCATCGCCGCGCCGAGCGAGATCGTCGTGACCACCTCATTCACCGTCGAGATCGGCGACACCAGCGGCACCA
TCCATTTCTGCATTCCGTACGCCACGCTGGAGCCGATCCGCGACACGCTGTACTCCACCGTGCAGGGGGATGCCAACGAG
CCCGACCGCCGCTGGGTCAAGCTGCTGACGCAGCAGATCCAGGCCGCCGAGGTCGACCTGGTGGCCGAGCTGGCGCAGGC
GCCGGCCACGGTCGAGCAGTTGCTCGCGCTGAAGCCGGGCGACTTCATCGAGCTCGACCTGGACCAGGTGGTCCACGCCA
AGGTGGACGGCGTGCCGGTGTTCGACTGCCACTACGGCACGAGCAACGGCAAGTACGCCATCAAGATCGATCAACTGCTG
ACGAACCAGGGCCCGTCCTGGCTGGGAGAACACCATGGCTGA

Upstream 100 bases:

>100_bases
CGCGTCGTGCCGTGCCTGCGGGCCGAGCGCTGGGCCGCTCCCAAGCCGGCCCGCGTCCCCTCGGGGGACCGGCTGACGTC
CTCGTCGGACGAGGGGCACC

Downstream 100 bases:

>100_bases
TGCCGCACCGAACGACGAACAGGACGCGATGGCCGCCGAGTGGGCCGCCGCGCTCGAGCAACAGTCGCCCGGCAGCGAGG
TCGTCACGACGGCCGAGCAG

Product: flagellar motor switch protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNQQILSQDEVDALLQGITGESQKLETEEVEQGGVRDYNLASQERIVRGRMPTMEIINERFSRNIRIGLFNFIRRTPEVA
VGTIKVQKYSAFLREIVVPTNFNIMAVRPLRGSGLIVCDPTLVFAVIDALFGGAGKFHTRIEGRDFSPTELRVISRLVEV
ISAEYKKAWAGVYPVELEYQRSEMQPQFATIAAPSEIVVTTSFTVEIGDTSGTIHFCIPYATLEPIRDTLYSTVQGDANE
PDRRWVKLLTQQIQAAEVDLVAELAQAPATVEQLLALKPGDFIELDLDQVVHAKVDGVPVFDCHYGTSNGKYAIKIDQLL
TNQGPSWLGEHHG

Sequences:

>Translated_333_residues
MNQQILSQDEVDALLQGITGESQKLETEEVEQGGVRDYNLASQERIVRGRMPTMEIINERFSRNIRIGLFNFIRRTPEVA
VGTIKVQKYSAFLREIVVPTNFNIMAVRPLRGSGLIVCDPTLVFAVIDALFGGAGKFHTRIEGRDFSPTELRVISRLVEV
ISAEYKKAWAGVYPVELEYQRSEMQPQFATIAAPSEIVVTTSFTVEIGDTSGTIHFCIPYATLEPIRDTLYSTVQGDANE
PDRRWVKLLTQQIQAAEVDLVAELAQAPATVEQLLALKPGDFIELDLDQVVHAKVDGVPVFDCHYGTSNGKYAIKIDQLL
TNQGPSWLGEHHG
>Mature_333_residues
MNQQILSQDEVDALLQGITGESQKLETEEVEQGGVRDYNLASQERIVRGRMPTMEIINERFSRNIRIGLFNFIRRTPEVA
VGTIKVQKYSAFLREIVVPTNFNIMAVRPLRGSGLIVCDPTLVFAVIDALFGGAGKFHTRIEGRDFSPTELRVISRLVEV
ISAEYKKAWAGVYPVELEYQRSEMQPQFATIAAPSEIVVTTSFTVEIGDTSGTIHFCIPYATLEPIRDTLYSTVQGDANE
PDRRWVKLLTQQIQAAEVDLVAELAQAPATVEQLLALKPGDFIELDLDQVVHAKVDGVPVFDCHYGTSNGKYAIKIDQLL
TNQGPSWLGEHHG

Specific function: FliM is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the mot

COG id: COG1868

COG function: function code N; Flagellar motor switch protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Bacterial flagellum basal body [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliM family [H]

Homologues:

Organism=Escherichia coli, GI1788255, Length=322, Percent_Identity=42.5465838509317, Blast_Score=294, Evalue=6e-81,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001689
- InterPro:   IPR001543 [H]

Pfam domain/function: PF02154 FliM; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 37076; Mature: 37076

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQILSQDEVDALLQGITGESQKLETEEVEQGGVRDYNLASQERIVRGRMPTMEIINER
CCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHH
FSRNIRIGLFNFIRRTPEVAVGTIKVQKYSAFLREIVVPTNFNIMAVRPLRGSGLIVCDP
HHCCEEEHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECH
TLVFAVIDALFGGAGKFHTRIEGRDFSPTELRVISRLVEVISAEYKKAWAGVYPVELEYQ
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
RSEMQPQFATIAAPSEIVVTTSFTVEIGDTSGTIHFCIPYATLEPIRDTLYSTVQGDANE
HHHCCCCEEEECCCCEEEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCC
PDRRWVKLLTQQIQAAEVDLVAELAQAPATVEQLLALKPGDFIELDLDQVVHAKVDGVPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEECHHHHHHHHCCCEEE
FDCHYGTSNGKYAIKIDQLLTNQGPSWLGEHHG
EEEECCCCCCEEEEEEHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNQQILSQDEVDALLQGITGESQKLETEEVEQGGVRDYNLASQERIVRGRMPTMEIINER
CCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHH
FSRNIRIGLFNFIRRTPEVAVGTIKVQKYSAFLREIVVPTNFNIMAVRPLRGSGLIVCDP
HHCCEEEHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECH
TLVFAVIDALFGGAGKFHTRIEGRDFSPTELRVISRLVEVISAEYKKAWAGVYPVELEYQ
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
RSEMQPQFATIAAPSEIVVTTSFTVEIGDTSGTIHFCIPYATLEPIRDTLYSTVQGDANE
HHHCCCCEEEECCCCEEEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCC
PDRRWVKLLTQQIQAAEVDLVAELAQAPATVEQLLALKPGDFIELDLDQVVHAKVDGVPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEECHHHHHHHHCCCEEE
FDCHYGTSNGKYAIKIDQLLTNQGPSWLGEHHG
EEEECCCCCCEEEEEEHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3519573; 9097040; 9278503; 2651416 [H]