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The map label for this gene is obg

Identifier: 124265706

GI number: 124265706

Start: 551174

End: 552286

Strand: Direct

Name: obg

Synonym: Mpe_A0513

Alternate gene names: 124265706

Gene position: 551174-552286 (Clockwise)

Preceding gene: 124265705

Following gene: 124265707

Centisome position: 13.63

GC content: 66.31

Gene sequence:

>1113_bases
ATGAAATTCGTTGACGAGGCTTACATCGACGTGATCGCCGGCAACGGCGGCAACGGCTGCGTGAGCTTTCGGCGCGAGAA
GTTCATCCCATTCGGCGGTCCGAACGGTGGCGATGGCGGGCGTGGCGGTAGCGTCTACGCGGTGGCCGACCGGAACCTCA
ACACCCTGATAGATTTCCGTTTCGCTCGGCGACACGAGGCCCGCCATGGTGAGCACGGCCGCGGTTCCGATCAGTTCGGC
GCGGCCGCAGAAGATATCGTGATGCGCATGCCGGTGGGCACCATCATCAGCGATGCCGAGACCGGCGCGCCGGTCGCCGA
ATTGCTTGAGCCGGGCGAGCGCATCCTGATCGCCAAGGGCGGCGACGGCGGCTTCGGCAACCTTCACTACAAGACCAGCA
CCAACCGCGCACCCCGCCAGAAGACACCGGGCTGGCCCGGCGAGCAGAAGAAGCTCAAGCTGGAACTGCGCGTGCTCGCC
GACGTGGGCCTGCTGGGCATGCCGAACGCCGGCAAGTCCACGCTGATCAGCGCGATCTCGAACGCCCGGCCGAAGATTGC
CGACTATCCCTTCACGACGCTGCATCCCAACCTTGGCGTGGTGCGCGTCGGACCGGAGCAGAGCTTCGTCGTTGCCGACG
TGCCCGGGTTGATCGAGGGAGCGGCCGAGGGCGCCGGGCTGGGCCACCGCTTCCTGCGTCACCTGCAGCGCACCCGGCTG
CTGCTTCACATGATCGACATGGCGCCGTTCGACGACACCGATCCGGTCGCACAGGCGAAGGCGATCGTCGCCGAGTTGAA
GAAGTACGACCCGGCGCTGTACGACAAGCCGCGCTGGCTGGTACTCAACAAGCTCGACGTCGTGCCGGCCGAGGAGCGTG
CCGCGCGCGTGAAGGATTTCGTCAAGCGCTTCAAGTGGAAGGGGCCGGTCTTCGAGATCTCGGCGCTGACGCGCGAGGGC
TGCGAGACGCTGGTGCAGGCGATCTACCAGCACGTGGCCAGCTATCAGACCCACTATGTCGATCCCGACGTGCGCTTCGC
CGAGCCCGAGGCCGACGAGAGCGATGACGAGCCCCGCTTTGCACCGCAGGCGGATGACCCGCGCTTCCGTTGA

Upstream 100 bases:

>100_bases
CGCGCTTGGCGCCGCGACGAAGCCCCGGCCCGCCGGGGCTTTTTCGTTGCAGAGCTCCAGATAACATCTCACTGGCTCGT
TCGAGCAACAGGCATTCCCC

Downstream 100 bases:

>100_bases
AGCGCGCCTGTTTCGGACCGAGAGAGTAGAGGCCGCATGTCCGAAGTGCTGCGTGGAGCGAGGCGCATCGTCGTCAAGGT
CGGATCCAGCCTCGTGACCA

Product: hypothetical protein

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKFVDEAYIDVIAGNGGNGCVSFRREKFIPFGGPNGGDGGRGGSVYAVADRNLNTLIDFRFARRHEARHGEHGRGSDQFG
AAAEDIVMRMPVGTIISDAETGAPVAELLEPGERILIAKGGDGGFGNLHYKTSTNRAPRQKTPGWPGEQKKLKLELRVLA
DVGLLGMPNAGKSTLISAISNARPKIADYPFTTLHPNLGVVRVGPEQSFVVADVPGLIEGAAEGAGLGHRFLRHLQRTRL
LLHMIDMAPFDDTDPVAQAKAIVAELKKYDPALYDKPRWLVLNKLDVVPAEERAARVKDFVKRFKWKGPVFEISALTREG
CETLVQAIYQHVASYQTHYVDPDVRFAEPEADESDDEPRFAPQADDPRFR

Sequences:

>Translated_370_residues
MKFVDEAYIDVIAGNGGNGCVSFRREKFIPFGGPNGGDGGRGGSVYAVADRNLNTLIDFRFARRHEARHGEHGRGSDQFG
AAAEDIVMRMPVGTIISDAETGAPVAELLEPGERILIAKGGDGGFGNLHYKTSTNRAPRQKTPGWPGEQKKLKLELRVLA
DVGLLGMPNAGKSTLISAISNARPKIADYPFTTLHPNLGVVRVGPEQSFVVADVPGLIEGAAEGAGLGHRFLRHLQRTRL
LLHMIDMAPFDDTDPVAQAKAIVAELKKYDPALYDKPRWLVLNKLDVVPAEERAARVKDFVKRFKWKGPVFEISALTREG
CETLVQAIYQHVASYQTHYVDPDVRFAEPEADESDDEPRFAPQADDPRFR
>Mature_370_residues
MKFVDEAYIDVIAGNGGNGCVSFRREKFIPFGGPNGGDGGRGGSVYAVADRNLNTLIDFRFARRHEARHGEHGRGSDQFG
AAAEDIVMRMPVGTIISDAETGAPVAELLEPGERILIAKGGDGGFGNLHYKTSTNRAPRQKTPGWPGEQKKLKLELRVLA
DVGLLGMPNAGKSTLISAISNARPKIADYPFTTLHPNLGVVRVGPEQSFVVADVPGLIEGAAEGAGLGHRFLRHLQRTRL
LLHMIDMAPFDDTDPVAQAKAIVAELKKYDPALYDKPRWLVLNKLDVVPAEERAARVKDFVKRFKWKGPVFEISALTREG
CETLVQAIYQHVASYQTHYVDPDVRFAEPEADESDDEPRFAPQADDPRFR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=323, Percent_Identity=40.5572755417957, Blast_Score=188, Evalue=6e-48,
Organism=Homo sapiens, GI111955139, Length=350, Percent_Identity=35.1428571428571, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI111955063, Length=250, Percent_Identity=34.4, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789574, Length=332, Percent_Identity=55.421686746988, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1787454, Length=257, Percent_Identity=26.4591439688716, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790615, Length=157, Percent_Identity=32.484076433121, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=328, Percent_Identity=39.6341463414634, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17552324, Length=310, Percent_Identity=30.3225806451613, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=32.3741007194245, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=195, Percent_Identity=36.4102564102564, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24585318, Length=307, Percent_Identity=37.785016286645, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI20129375, Length=329, Percent_Identity=37.6899696048632, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24640873, Length=135, Percent_Identity=31.1111111111111, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640877, Length=135, Percent_Identity=31.1111111111111, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640875, Length=135, Percent_Identity=31.1111111111111, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_METPP (A2SD36)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019710.1
- ProteinModelPortal:   A2SD36
- SMR:   A2SD36
- STRING:   A2SD36
- GeneID:   4787089
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0513
- NMPDR:   fig|279263.3.peg.2757
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- PhylomeDB:   A2SD36
- ProtClustDB:   PRK12299
- BioCyc:   MPET420662:MPE_A0513-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 40576; Mature: 40576

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAYIDVIAGNGGNGCVSFRREKFIPFGGPNGGDGGRGGSVYAVADRNLNTLIDFR
CCCCCCEEEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
FARRHEARHGEHGRGSDQFGAAAEDIVMRMPVGTIISDAETGAPVAELLEPGERILIAKG
HHHHHHHCCCCCCCCCCHHCCHHHHHHHHCCCCHHHCCCCCCCCHHHHHCCCCEEEEEEC
GDGGFGNLHYKTSTNRAPRQKTPGWPGEQKKLKLELRVLADVGLLGMPNAGKSTLISAIS
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHH
NARPKIADYPFTTLHPNLGVVRVGPEQSFVVADVPGLIEGAAEGAGLGHRFLRHLQRTRL
CCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHH
LLHMIDMAPFDDTDPVAQAKAIVAELKKYDPALYDKPRWLVLNKLDVVPAEERAARVKDF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
VKRFKWKGPVFEISALTREGCETLVQAIYQHVASYQTHYVDPDVRFAEPEADESDDEPRF
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCC
APQADDPRFR
CCCCCCCCCC
>Mature Secondary Structure
MKFVDEAYIDVIAGNGGNGCVSFRREKFIPFGGPNGGDGGRGGSVYAVADRNLNTLIDFR
CCCCCCEEEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
FARRHEARHGEHGRGSDQFGAAAEDIVMRMPVGTIISDAETGAPVAELLEPGERILIAKG
HHHHHHHCCCCCCCCCCHHCCHHHHHHHHCCCCHHHCCCCCCCCHHHHHCCCCEEEEEEC
GDGGFGNLHYKTSTNRAPRQKTPGWPGEQKKLKLELRVLADVGLLGMPNAGKSTLISAIS
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHH
NARPKIADYPFTTLHPNLGVVRVGPEQSFVVADVPGLIEGAAEGAGLGHRFLRHLQRTRL
CCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHH
LLHMIDMAPFDDTDPVAQAKAIVAELKKYDPALYDKPRWLVLNKLDVVPAEERAARVKDF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
VKRFKWKGPVFEISALTREGCETLVQAIYQHVASYQTHYVDPDVRFAEPEADESDDEPRF
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCC
APQADDPRFR
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA