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The map label for this gene is ftsZ [H]

Identifier: 124265660

GI number: 124265660

Start: 508003

End: 509220

Strand: Direct

Name: ftsZ [H]

Synonym: Mpe_A0467

Alternate gene names: 124265660

Gene position: 508003-509220 (Clockwise)

Preceding gene: 124265659

Following gene: 124265661

Centisome position: 12.56

GC content: 68.97

Gene sequence:

>1218_bases
ATGGCCATCGAGATGATTGAAGAATTCGAGCTCGGCACGAAGATCAAGGTGATCGGCGTGGGCGGCGGCGGCGGCAACGC
TGTCGAGCACATGATCAACGAGGGCGTGCAGGGCGTGGAGTTCATCTGCGCGAACACCGACGCGCAGGCGCTGCACCGCT
CCAAGGCCGACCAGCTCATCCAGCTCGGGAGCACCGGCCTGGGCGCGGGCTCCAAGCCGGCCGCCGGCAAGGCCGCGGCC
GACGAAGCCGAGGGCCGCATCCGCGACGCGATCGCGGGCGCCAACATGATCTTCCTGACTGCCGGCATGGGCGGCGGCAC
CGGCACCGGCGCCGCGCCGGTGATCGCGCGCGTGGCCAAGGAGATGGGCATCCTGACGGTGGGCGTGGTGACCAAGCCCT
TCGACTTCGAGGGCGGCCGGCGCATGAAGCAGGCCGAGGCCGGCCTGCAGGAGCTGGAAGCCAACGTCGACTCGCTGATC
GTGGTGCTCAACGAGAAGTTGCTCGAGGTGCTGGGAGACGACGTGTCGCAGGACCAGGCCTTCAAGCAGGCCAACGACGT
GCTGAAGAATGCCGTGGGCGGCATTGCCGACATCATCCACATCGATGCATCGATCAACGTCGACTTCGAGGACGTGAAGA
CGGTGATGAGCGAGCCCGGCAAGGCGATGATGGGCACCGCGATCGCGACCGGACCGGACCGCGCCAACAAGGCGGCCGAC
TCGGCGGTGGCCTGCCCGCTGCTCGAGGGCATCGACCTGTCGGGCGCGCGCGGTGTGCTGGTGCTGATCGCGGCGAGCCG
CGCCAGCCTGAAGCTGAGCGAGAGCAAGAACGCGATGAACACCATCCGCCGTTACGCCGCGGAAGACGCCCACGTGATCT
TCGGCGCCGCCTACGACGAGAGCCTGGGCGACCAGCTGCGCGTGACCGTGATCGCCACCGGACTCGCGCCGGCCCGCCGT
GTGCAGGCGCCGATGACGGTGGTGCACAACGCCACGCTGCAGCGGACCGGCACCGACAACATCCCGGTGCTGAACCAGCC
GCTGCACACGCAGGGCGGGCTGTCCGCCGCGCCGACCCAGCACGACTACGCCGGCATGCAGGTGCCGAGCGTGTGGCGCA
GCGGGCGCACCCAGGCCGCGGCGAAGGTGGATGCGCTGGCGAGCAACGGCATGGACGAGATCGAGATCCCGGCGTTCCTG
CGCAAGCAAGCCGATTGA

Upstream 100 bases:

>100_bases
CCTGTTCGGCCGCGTCAAGGATTGGTTCATCGGGAATTTTTAGGGCGTCATCCAGCCCACGTTTTCAACCGGCAACTGCA
TCAGACGAAGGAGGTCCACC

Downstream 100 bases:

>100_bases
TGACGACCACCCCCGTTGCGCCTTCGGCGCTCCCCCTCGAGGGGGCGGCGCTGGCGGGCCGGCGGAGCCGGACCCGCGGC
GCCTGCTGGGTGAAGGCAAC

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAIEMIEEFELGTKIKVIGVGGGGGNAVEHMINEGVQGVEFICANTDAQALHRSKADQLIQLGSTGLGAGSKPAAGKAAA
DEAEGRIRDAIAGANMIFLTAGMGGGTGTGAAPVIARVAKEMGILTVGVVTKPFDFEGGRRMKQAEAGLQELEANVDSLI
VVLNEKLLEVLGDDVSQDQAFKQANDVLKNAVGGIADIIHIDASINVDFEDVKTVMSEPGKAMMGTAIATGPDRANKAAD
SAVACPLLEGIDLSGARGVLVLIAASRASLKLSESKNAMNTIRRYAAEDAHVIFGAAYDESLGDQLRVTVIATGLAPARR
VQAPMTVVHNATLQRTGTDNIPVLNQPLHTQGGLSAAPTQHDYAGMQVPSVWRSGRTQAAAKVDALASNGMDEIEIPAFL
RKQAD

Sequences:

>Translated_405_residues
MAIEMIEEFELGTKIKVIGVGGGGGNAVEHMINEGVQGVEFICANTDAQALHRSKADQLIQLGSTGLGAGSKPAAGKAAA
DEAEGRIRDAIAGANMIFLTAGMGGGTGTGAAPVIARVAKEMGILTVGVVTKPFDFEGGRRMKQAEAGLQELEANVDSLI
VVLNEKLLEVLGDDVSQDQAFKQANDVLKNAVGGIADIIHIDASINVDFEDVKTVMSEPGKAMMGTAIATGPDRANKAAD
SAVACPLLEGIDLSGARGVLVLIAASRASLKLSESKNAMNTIRRYAAEDAHVIFGAAYDESLGDQLRVTVIATGLAPARR
VQAPMTVVHNATLQRTGTDNIPVLNQPLHTQGGLSAAPTQHDYAGMQVPSVWRSGRTQAAAKVDALASNGMDEIEIPAFL
RKQAD
>Mature_404_residues
AIEMIEEFELGTKIKVIGVGGGGGNAVEHMINEGVQGVEFICANTDAQALHRSKADQLIQLGSTGLGAGSKPAAGKAAAD
EAEGRIRDAIAGANMIFLTAGMGGGTGTGAAPVIARVAKEMGILTVGVVTKPFDFEGGRRMKQAEAGLQELEANVDSLIV
VLNEKLLEVLGDDVSQDQAFKQANDVLKNAVGGIADIIHIDASINVDFEDVKTVMSEPGKAMMGTAIATGPDRANKAADS
AVACPLLEGIDLSGARGVLVLIAASRASLKLSESKNAMNTIRRYAAEDAHVIFGAAYDESLGDQLRVTVIATGLAPARRV
QAPMTVVHNATLQRTGTDNIPVLNQPLHTQGGLSAAPTQHDYAGMQVPSVWRSGRTQAAAKVDALASNGMDEIEIPAFLR
KQAD

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=406, Percent_Identity=51.7241379310345, Blast_Score=304, Evalue=9e-84,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 42010; Mature: 41879

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEMIEEFELGTKIKVIGVGGGGGNAVEHMINEGVQGVEFICANTDAQALHRSKADQLI
CCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHH
QLGSTGLGAGSKPAAGKAAADEAEGRIRDAIAGANMIFLTAGMGGGTGTGAAPVIARVAK
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHH
EMGILTVGVVTKPFDFEGGRRMKQAEAGLQELEANVDSLIVVLNEKLLEVLGDDVSQDQA
HCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHH
FKQANDVLKNAVGGIADIIHIDASINVDFEDVKTVMSEPGKAMMGTAIATGPDRANKAAD
HHHHHHHHHHHHCCCEEEEEECCEECCCHHHHHHHHCCCCCCHHCCEEECCCCHHHHHHC
SAVACPLLEGIDLSGARGVLVLIAASRASLKLSESKNAMNTIRRYAAEDAHVIFGAAYDE
CHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCC
SLGDQLRVTVIATGLAPARRVQAPMTVVHNATLQRTGTDNIPVLNQPLHTQGGLSAAPTQ
CCCCCEEEEEEEECCCCHHHHCCCHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC
HDYAGMQVPSVWRSGRTQAAAKVDALASNGMDEIEIPAFLRKQAD
CCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
AIEMIEEFELGTKIKVIGVGGGGGNAVEHMINEGVQGVEFICANTDAQALHRSKADQLI
CHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHH
QLGSTGLGAGSKPAAGKAAADEAEGRIRDAIAGANMIFLTAGMGGGTGTGAAPVIARVAK
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHH
EMGILTVGVVTKPFDFEGGRRMKQAEAGLQELEANVDSLIVVLNEKLLEVLGDDVSQDQA
HCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHH
FKQANDVLKNAVGGIADIIHIDASINVDFEDVKTVMSEPGKAMMGTAIATGPDRANKAAD
HHHHHHHHHHHHCCCEEEEEECCEECCCHHHHHHHHCCCCCCHHCCEEECCCCHHHHHHC
SAVACPLLEGIDLSGARGVLVLIAASRASLKLSESKNAMNTIRRYAAEDAHVIFGAAYDE
CHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCC
SLGDQLRVTVIATGLAPARRVQAPMTVVHNATLQRTGTDNIPVLNQPLHTQGGLSAAPTQ
CCCCCEEEEEEEECCCCHHHHCCCHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC
HDYAGMQVPSVWRSGRTQAAAKVDALASNGMDEIEIPAFLRKQAD
CCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11443086; 12219091 [H]