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The map label for this gene is corA [H]

Identifier: 124265420

GI number: 124265420

Start: 243818

End: 244774

Strand: Direct

Name: corA [H]

Synonym: Mpe_A0227

Alternate gene names: 124265420

Gene position: 243818-244774 (Clockwise)

Preceding gene: 124265416

Following gene: 124265421

Centisome position: 6.03

GC content: 62.7

Gene sequence:

>957_bases
ATGCTGAACGTCTTCACGCTCGCCAATGGGCGGCTGTTCCAAGAAGAAATCGAGAGCGCGGCAGCGCTCGCCCATGTGCG
GCCGGTGTGGGTCGACCTGGAAAGCCCGACGCCCGAGGAAAAGGGTTGGCTGGCCGGTCGCTTCGGACTGCAGATTCCCG
AGAACATCGTCGACGACGATCTGGAGGAGTCCGCCCGCTTCTACGAGGAAGACAACGGCGAACTGCACATCCGCTCCGAC
TTCCTGATCCACGACGAGGCGACACGAAATGTCCGCGTGGCGTTCATCCTGCACGACAAGGTGCTTTTTTCGGTGCATGC
CGAGGACCTGCCGGTGTTCCGCCTGCTGCGGTTGCGGGCGCGCCGCACGCCGGCGCTGATCGAAGACGCCAAGGACGTGC
TGCTCAAGCTCTACGACGCCGACGCCGAGTACTCGGCCGATTCGCTCGAGGGCATCTACGATGAATTGGAGAAGGTGTCG
TCGCGCGTGCTGCAGTCGGAGGTGAACGACCAGACCGCCGCCGAGGTGCTGGCCGCCATCGCGCGCCAGGAAGACTTGAA
CGGCCGCATCCGCCGCAACGTGATGGACACGCGACGCGCGGTCAGCTTCATGATGCGCAGCCGCCTGCTCAATGCCGAGC
AGTTCGAGGAGGCGCGCCAGATCCTGCGCGACATCGACTCGCTGGATTCGCACACCGCCTTCCTGTTCGACAAGATCAAC
TTCCTGATGGATGCCATCGTCGGCTTCATCAACATCAACCAGAACAAGATCATCAAGTTGTTCTCGGTGGCCAGCGTCGC
GCTGCTGCCGCCGACGCTGATCGCCAGCATCTACGGCATGAACTTCAAGGCGATGCCGGAACTCGACTGGAGCCTGGGCT
ATCCGTACGCGCTGGGCCTGATGGTCGCGTCGGTGATCGCGCCGTTCTGGTATTTCCGTCGCAAGGGTTGGCTGTGA

Upstream 100 bases:

>100_bases
GGAGTGAGACGGTCTCGATCTCACTTCCCAAGCCGACCCCGAGCCCAGCTTCCGGGGTCGAATCCGCGGCGCGTCGGCCC
GCGCGGTTGTTGGAGTTCGC

Downstream 100 bases:

>100_bases
TGGCGGCGCGGGGTCTCCGCGCTGCCGGTGAGACGCGATGAGCTCCGATGCTCCCGTGGGCCGCGGGCTCTGGCGCATCG
GGGCGGGCACGACGCTGGTG

Product: transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MLNVFTLANGRLFQEEIESAAALAHVRPVWVDLESPTPEEKGWLAGRFGLQIPENIVDDDLEESARFYEEDNGELHIRSD
FLIHDEATRNVRVAFILHDKVLFSVHAEDLPVFRLLRLRARRTPALIEDAKDVLLKLYDADAEYSADSLEGIYDELEKVS
SRVLQSEVNDQTAAEVLAAIARQEDLNGRIRRNVMDTRRAVSFMMRSRLLNAEQFEEARQILRDIDSLDSHTAFLFDKIN
FLMDAIVGFININQNKIIKLFSVASVALLPPTLIASIYGMNFKAMPELDWSLGYPYALGLMVASVIAPFWYFRRKGWL

Sequences:

>Translated_318_residues
MLNVFTLANGRLFQEEIESAAALAHVRPVWVDLESPTPEEKGWLAGRFGLQIPENIVDDDLEESARFYEEDNGELHIRSD
FLIHDEATRNVRVAFILHDKVLFSVHAEDLPVFRLLRLRARRTPALIEDAKDVLLKLYDADAEYSADSLEGIYDELEKVS
SRVLQSEVNDQTAAEVLAAIARQEDLNGRIRRNVMDTRRAVSFMMRSRLLNAEQFEEARQILRDIDSLDSHTAFLFDKIN
FLMDAIVGFININQNKIIKLFSVASVALLPPTLIASIYGMNFKAMPELDWSLGYPYALGLMVASVIAPFWYFRRKGWL
>Mature_318_residues
MLNVFTLANGRLFQEEIESAAALAHVRPVWVDLESPTPEEKGWLAGRFGLQIPENIVDDDLEESARFYEEDNGELHIRSD
FLIHDEATRNVRVAFILHDKVLFSVHAEDLPVFRLLRLRARRTPALIEDAKDVLLKLYDADAEYSADSLEGIYDELEKVS
SRVLQSEVNDQTAAEVLAAIARQEDLNGRIRRNVMDTRRAVSFMMRSRLLNAEQFEEARQILRDIDSLDSHTAFLFDKIN
FLMDAIVGFININQNKIIKLFSVASVALLPPTLIASIYGMNFKAMPELDWSLGYPYALGLMVASVIAPFWYFRRKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=320, Percent_Identity=44.6875, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36350; Mature: 36350

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNVFTLANGRLFQEEIESAAALAHVRPVWVDLESPTPEEKGWLAGRFGLQIPENIVDDD
CCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHCCC
LEESARFYEEDNGELHIRSDFLIHDEATRNVRVAFILHDKVLFSVHAEDLPVFRLLRLRA
HHHHHHHHHCCCCEEEEEECEEEECCCCCCEEEEEEEECCEEEEECCCCCHHHHHHHHHH
RRTPALIEDAKDVLLKLYDADAEYSADSLEGIYDELEKVSSRVLQSEVNDQTAAEVLAAI
HCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ARQEDLNGRIRRNVMDTRRAVSFMMRSRLLNAEQFEEARQILRDIDSLDSHTAFLFDKIN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FLMDAIVGFININQNKIIKLFSVASVALLPPTLIASIYGMNFKAMPELDWSLGYPYALGL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCCCCCCCHHHHHH
MVASVIAPFWYFRRKGWL
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLNVFTLANGRLFQEEIESAAALAHVRPVWVDLESPTPEEKGWLAGRFGLQIPENIVDDD
CCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHCCC
LEESARFYEEDNGELHIRSDFLIHDEATRNVRVAFILHDKVLFSVHAEDLPVFRLLRLRA
HHHHHHHHHCCCCEEEEEECEEEECCCCCCEEEEEEEECCEEEEECCCCCHHHHHHHHHH
RRTPALIEDAKDVLLKLYDADAEYSADSLEGIYDELEKVSSRVLQSEVNDQTAAEVLAAI
HCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ARQEDLNGRIRRNVMDTRRAVSFMMRSRLLNAEQFEEARQILRDIDSLDSHTAFLFDKIN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FLMDAIVGFININQNKIIKLFSVASVALLPPTLIASIYGMNFKAMPELDWSLGYPYALGL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCCCCCCCHHHHHH
MVASVIAPFWYFRRKGWL
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]