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The map label for this gene is fur [H]

Identifier: 124265416

GI number: 124265416

Start: 240781

End: 241218

Strand: Direct

Name: fur [H]

Synonym: Mpe_A0223

Alternate gene names: 124265416

Gene position: 240781-241218 (Clockwise)

Preceding gene: 124265406

Following gene: 124265420

Centisome position: 5.95

GC content: 64.84

Gene sequence:

>438_bases
ATGACCACCCATGCCGAAGACCTCAAGAGCAGCGGACTCAAGGCCACCCTGCCGCGCCTCAAGATCCTCGAGGTGTTCCA
GACCTCGGCGGTGCGCCACCTGACGGCCGAGGACGTCTACAAGCACTTGCTGGCCGACGGTTCCGACATCGGCCTGGCCA
CGGTCTACCGGGTGCTGATGCAGTTCGAGCAGGCCGGCATCCTGTCTCGCAATCACTTCGAGTCGGGCAAGTCGGTGTTC
GAGCTCAACGAGGGCAAGCACCATGACCATCTGGTGTGCGTCGTGTGCGGGCGGGTCGAGGAGTTCTACGACGCCGAGAT
CGAGAAGCGCCAGCTGCAGATTGCCCGCGAGCGAGGCTACGAGCTGCAGGACCACTCGCTCGCGCTCTACGTGATCTGCG
GGCGCGACGGCTGCAAGGGCAGCAACTCGCCGCGCTGA

Upstream 100 bases:

>100_bases
GGGCCGCTGCGAGAGCGACGGGGTGCCCGCCGCACCAGGGCCGCAGGCTCGATATGATCCAAGAATTCTAGTGGAGCCCA
CCTGCCCCGAGGACCTGCCG

Downstream 100 bases:

>100_bases
CCGACGTTCAGATCGGTTCGTCGCCTTCCATCGCGATGCGATGGCGGGCGATGAACTCCTGGTAGGTGTCGATGCCGCGC
AGCTTCAGGATGGTGTTGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MTTHAEDLKSSGLKATLPRLKILEVFQTSAVRHLTAEDVYKHLLADGSDIGLATVYRVLMQFEQAGILSRNHFESGKSVF
ELNEGKHHDHLVCVVCGRVEEFYDAEIEKRQLQIARERGYELQDHSLALYVICGRDGCKGSNSPR

Sequences:

>Translated_145_residues
MTTHAEDLKSSGLKATLPRLKILEVFQTSAVRHLTAEDVYKHLLADGSDIGLATVYRVLMQFEQAGILSRNHFESGKSVF
ELNEGKHHDHLVCVVCGRVEEFYDAEIEKRQLQIARERGYELQDHSLALYVICGRDGCKGSNSPR
>Mature_144_residues
TTHAEDLKSSGLKATLPRLKILEVFQTSAVRHLTAEDVYKHLLADGSDIGLATVYRVLMQFEQAGILSRNHFESGKSVFE
LNEGKHHDHLVCVVCGRVEEFYDAEIEKRQLQIARERGYELQDHSLALYVICGRDGCKGSNSPR

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=139, Percent_Identity=56.1151079136691, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16343; Mature: 16212

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHAEDLKSSGLKATLPRLKILEVFQTSAVRHLTAEDVYKHLLADGSDIGLATVYRVLM
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHH
QFEQAGILSRNHFESGKSVFELNEGKHHDHLVCVVCGRVEEFYDAEIEKRQLQIARERGY
HHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCC
ELQDHSLALYVICGRDGCKGSNSPR
CCCCCCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TTHAEDLKSSGLKATLPRLKILEVFQTSAVRHLTAEDVYKHLLADGSDIGLATVYRVLM
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHH
QFEQAGILSRNHFESGKSVFELNEGKHHDHLVCVVCGRVEEFYDAEIEKRQLQIARERGY
HHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCC
ELQDHSLALYVICGRDGCKGSNSPR
CCCCCCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA