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The map label for this gene is surA [H]

Identifier: 124265396

GI number: 124265396

Start: 218898

End: 220211

Strand: Direct

Name: surA [H]

Synonym: Mpe_A0203

Alternate gene names: 124265396

Gene position: 218898-220211 (Clockwise)

Preceding gene: 124265395

Following gene: 124265397

Centisome position: 5.41

GC content: 69.94

Gene sequence:

>1314_bases
ATGTTGCCGAAGTCTTCTCCCCCTTGCGCCAGAGGGCTGCTGCTCGCGCTGCTCTGCAGCCTCTTCGTCGCGAACGCGGT
CGCGCAGCCGTCGCCGGTCCGCTCGGCCGACTACATCGTCGCGATCGTCGACCGGGAACTGGTCACCAATGCAGAAGTCC
AGCAGCGGCTGGCTGCGCTGCGGCGCGAGGCGGCTCAGAGTGGGCAGGCACTACCGCCTGACGACGAATTGCGCCGCCGC
ATGCTCGACACCCTGATCGACGAACGCGCCCAGCTCAGTGCGGCCCGCGAAAGCGGCGTGCGCATCGACGAGGCCGAGCT
CGACCGCACCGTCGGCAACGTCGCCGCGCAGAACCGCATCACGCTGGCGCAGCTGCGCGAGCGCCTGCAGCGCGACGGCA
TCGAGTTCTCGCGCTTTCGCAGCAACCTGCGGGATCAGTTGCTGCTCGAGCGGGTGCGAGAACGCGAGGTCCAGTCGCGC
ATCAAGATCAGCGACAGCGAGGTCGAGACCCTGCTGGCCAGTCGTGCCAGCGGCGTGGCCCCGCCGCAGTTCAATGTCGC
GCAGCTGCTGATCGGCGTGCCCGAGGGCGCCGGCGAGGCCGAGCTGGCGCAGCGCCGCGTGCTCGCCGAACAGGCTCTGC
AGCGTGCCCGCGGGGGCGAGGACTTTGCGCGTCTCGTCAACGAGCTGTCGACCGGGTCGAAGGAGCAGGGTGGGGCCCTG
GGCCTGCGCACGCTCGATCGGCTGCCCGACCTGTTTGCTGACGCGGTGCGCGATCTGCGCGGCGGCGCCATCGTGCCGCA
GGTGTTGCAGTCGGGCGCCGGCTTTCATGTGCTGAAGGTGGTGGAGCGGCGCGATGGCGGCATGATGGTGCCGCAGACGC
GCGCTCGCCACATCCTGCTGCGGACCTCGGCACAACTGACGCAGTCGGCCGCCGTGGCCCGGCTGGCGGAGTTCAAGCAG
CAGGTCGACAGCGGCAAGGCCAGCTTCGCCCAGCTCGCCCGCGAGAACTCCGAGGACGGCAGCGCGGCCCAGGGCGGCGA
ACTCGGCTGGGCCTCGCCGGGCCAGTTCGTGCCGGAGTTCGAGGAGGCCATGAAGGCACTCGGCATCAACCAGGTGTCGG
ATCCGGTGGTCTCGCGGTTTGGCGTGCACCTGATCCAGGTGCTGGAGCGTCGCAGCGTCCCGGTCGACCGGAAGCAGCAG
CGCGAGATCGCGCGCAATGTCCTGCGCGAGCAGAAGTTCGAGAGTGCCTACCAGGAGTGGGCGCGCGATGTGCGGGCCCG
CGCCTACGTGGAGATGAGGGAGCCTCCGCAGTGA

Upstream 100 bases:

>100_bases
TTGAAGGTGCTGAGGGAGAATGTGCCCGGTTACCGTTTGCTGCGCGACGACAGTCCGGTGGTCGCGCCGGCCCTCTCGAC
CCCCTGAGCTGCTGTCATCG

Downstream 100 bases:

>100_bases
GCGTGAGGTCGGTGACAGTGGCCCCGCGGCAGGCGTGAAGCACATCGCCCGCAAGCGCTTCGGCCAGCATTTCCTGTCCG
ATGCGGCGGTGGTCGATGCG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MLPKSSPPCARGLLLALLCSLFVANAVAQPSPVRSADYIVAIVDRELVTNAEVQQRLAALRREAAQSGQALPPDDELRRR
MLDTLIDERAQLSAARESGVRIDEAELDRTVGNVAAQNRITLAQLRERLQRDGIEFSRFRSNLRDQLLLERVREREVQSR
IKISDSEVETLLASRASGVAPPQFNVAQLLIGVPEGAGEAELAQRRVLAEQALQRARGGEDFARLVNELSTGSKEQGGAL
GLRTLDRLPDLFADAVRDLRGGAIVPQVLQSGAGFHVLKVVERRDGGMMVPQTRARHILLRTSAQLTQSAAVARLAEFKQ
QVDSGKASFAQLARENSEDGSAAQGGELGWASPGQFVPEFEEAMKALGINQVSDPVVSRFGVHLIQVLERRSVPVDRKQQ
REIARNVLREQKFESAYQEWARDVRARAYVEMREPPQ

Sequences:

>Translated_437_residues
MLPKSSPPCARGLLLALLCSLFVANAVAQPSPVRSADYIVAIVDRELVTNAEVQQRLAALRREAAQSGQALPPDDELRRR
MLDTLIDERAQLSAARESGVRIDEAELDRTVGNVAAQNRITLAQLRERLQRDGIEFSRFRSNLRDQLLLERVREREVQSR
IKISDSEVETLLASRASGVAPPQFNVAQLLIGVPEGAGEAELAQRRVLAEQALQRARGGEDFARLVNELSTGSKEQGGAL
GLRTLDRLPDLFADAVRDLRGGAIVPQVLQSGAGFHVLKVVERRDGGMMVPQTRARHILLRTSAQLTQSAAVARLAEFKQ
QVDSGKASFAQLARENSEDGSAAQGGELGWASPGQFVPEFEEAMKALGINQVSDPVVSRFGVHLIQVLERRSVPVDRKQQ
REIARNVLREQKFESAYQEWARDVRARAYVEMREPPQ
>Mature_437_residues
MLPKSSPPCARGLLLALLCSLFVANAVAQPSPVRSADYIVAIVDRELVTNAEVQQRLAALRREAAQSGQALPPDDELRRR
MLDTLIDERAQLSAARESGVRIDEAELDRTVGNVAAQNRITLAQLRERLQRDGIEFSRFRSNLRDQLLLERVREREVQSR
IKISDSEVETLLASRASGVAPPQFNVAQLLIGVPEGAGEAELAQRRVLAEQALQRARGGEDFARLVNELSTGSKEQGGAL
GLRTLDRLPDLFADAVRDLRGGAIVPQVLQSGAGFHVLKVVERRDGGMMVPQTRARHILLRTSAQLTQSAAVARLAEFKQ
QVDSGKASFAQLARENSEDGSAAQGGELGWASPGQFVPEFEEAMKALGINQVSDPVVSRFGVHLIQVLERRSVPVDRKQQ
REIARNVLREQKFESAYQEWARDVRARAYVEMREPPQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=387, Percent_Identity=35.4005167958656, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48235; Mature: 48235

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKSSPPCARGLLLALLCSLFVANAVAQPSPVRSADYIVAIVDRELVTNAEVQQRLAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
RREAAQSGQALPPDDELRRRMLDTLIDERAQLSAARESGVRIDEAELDRTVGNVAAQNRI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCH
TLAQLRERLQRDGIEFSRFRSNLRDQLLLERVREREVQSRIKISDSEVETLLASRASGVA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
PPQFNVAQLLIGVPEGAGEAELAQRRVLAEQALQRARGGEDFARLVNELSTGSKEQGGAL
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCH
GLRTLDRLPDLFADAVRDLRGGAIVPQVLQSGAGFHVLKVVERRDGGMMVPQTRARHILL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
RTSAQLTQSAAVARLAEFKQQVDSGKASFAQLARENSEDGSAAQGGELGWASPGQFVPEF
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
EEAMKALGINQVSDPVVSRFGVHLIQVLERRSVPVDRKQQREIARNVLREQKFESAYQEW
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARDVRARAYVEMREPPQ
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLPKSSPPCARGLLLALLCSLFVANAVAQPSPVRSADYIVAIVDRELVTNAEVQQRLAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
RREAAQSGQALPPDDELRRRMLDTLIDERAQLSAARESGVRIDEAELDRTVGNVAAQNRI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCH
TLAQLRERLQRDGIEFSRFRSNLRDQLLLERVREREVQSRIKISDSEVETLLASRASGVA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
PPQFNVAQLLIGVPEGAGEAELAQRRVLAEQALQRARGGEDFARLVNELSTGSKEQGGAL
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCH
GLRTLDRLPDLFADAVRDLRGGAIVPQVLQSGAGFHVLKVVERRDGGMMVPQTRARHILL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
RTSAQLTQSAAVARLAEFKQQVDSGKASFAQLARENSEDGSAAQGGELGWASPGQFVPEF
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
EEAMKALGINQVSDPVVSRFGVHLIQVLERRSVPVDRKQQREIARNVLREQKFESAYQEW
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARDVRARAYVEMREPPQ
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA