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The map label for this gene is atpH

Identifier: 124265387

GI number: 124265387

Start: 208758

End: 209291

Strand: Direct

Name: atpH

Synonym: Mpe_A0194

Alternate gene names: 124265387

Gene position: 208758-209291 (Clockwise)

Preceding gene: 124265386

Following gene: 124265388

Centisome position: 5.16

GC content: 70.97

Gene sequence:

>534_bases
ATGGCAGAACTCGCAACCATCGCGCGCCCCTACGCCGAGGCCCTGTTCCGCGCCGCGCCGAAAGGTGAGGCGGCCGGCTG
GGCCGAGCAGGTGGCCGCGCTCGGCGCGGTCGCTGCCGACCCGGTGCTGCGGCAGTTCGCCGACAGCCCGAAGGTGGCGG
CCCAGCAGGTGTTCGATCTCGTCGCCGGCGTCACCAAGCAGACGCTGGTGCCGGGTGTGCAGAACCTGCTGCGCGCCATG
ATCGAGAACGGGCGCCTGTCGGCGCTGCCCGAGGTCGCCGCGCAGTTCCACGCGCTGGTCAACGCGAGTTCGGGCGTTTC
CGACGCCATCGTCTACAGCGCCTTCCCCATCGAGCCGGCCGCGCTGGCCGACCTGGTGGCGACGCTGGAGAAGCGCTTCG
GGCGCAGGCTGTCCGCCACGGTGCAGCTCGAGCCCGAACTGATCGGTGGTGTCCGGGTGGTGGTCGGCGACGAGGTGCTC
GACACCTCGGTCAAGGCCCGTCTCGAGCACATGAAGGTCGCGTTGACCGCCTGA

Upstream 100 bases:

>100_bases
CCGCGCTGGCCGTCAAGGGCGCCGAGCAGATCCTCAAGCGCGAAGTCAACGCCGGCGTCCACGCCGACTTGCTGTCGCGT
CTGAAGACGGAGCTCTGACG

Downstream 100 bases:

>100_bases
GCCGTATTTGAATCAATCCGCCCGGAGGCGCGAGTCGTCGGGTTCGGTCGTCGACGCCGCAGGGCGCCTGAAGAGACTGG
GAGCTAGCCATGCAACTGAA

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MAELATIARPYAEALFRAAPKGEAAGWAEQVAALGAVAADPVLRQFADSPKVAAQQVFDLVAGVTKQTLVPGVQNLLRAM
IENGRLSALPEVAAQFHALVNASSGVSDAIVYSAFPIEPAALADLVATLEKRFGRRLSATVQLEPELIGGVRVVVGDEVL
DTSVKARLEHMKVALTA

Sequences:

>Translated_177_residues
MAELATIARPYAEALFRAAPKGEAAGWAEQVAALGAVAADPVLRQFADSPKVAAQQVFDLVAGVTKQTLVPGVQNLLRAM
IENGRLSALPEVAAQFHALVNASSGVSDAIVYSAFPIEPAALADLVATLEKRFGRRLSATVQLEPELIGGVRVVVGDEVL
DTSVKARLEHMKVALTA
>Mature_176_residues
AELATIARPYAEALFRAAPKGEAAGWAEQVAALGAVAADPVLRQFADSPKVAAQQVFDLVAGVTKQTLVPGVQNLLRAMI
ENGRLSALPEVAAQFHALVNASSGVSDAIVYSAFPIEPAALADLVATLEKRFGRRLSATVQLEPELIGGVRVVVGDEVLD
TSVKARLEHMKVALTA

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Escherichia coli, GI1790173, Length=172, Percent_Identity=33.1395348837209, Blast_Score=90, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6320504, Length=173, Percent_Identity=26.5895953757225, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_METPP (A2SC67)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019391.1
- STRING:   A2SC67
- GeneID:   4783518
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0194
- NMPDR:   fig|279263.3.peg.259
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   FIAICGE
- PhylomeDB:   A2SC67
- ProtClustDB:   PRK05758
- BioCyc:   MPET420662:MPE_A0194-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 18539; Mature: 18407

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELATIARPYAEALFRAAPKGEAAGWAEQVAALGAVAADPVLRQFADSPKVAAQQVFDL
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VAGVTKQTLVPGVQNLLRAMIENGRLSALPEVAAQFHALVNASSGVSDAIVYSAFPIEPA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHH
ALADLVATLEKRFGRRLSATVQLEPELIGGVRVVVGDEVLDTSVKARLEHMKVALTA
HHHHHHHHHHHHHCCHHHHEEEECHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AELATIARPYAEALFRAAPKGEAAGWAEQVAALGAVAADPVLRQFADSPKVAAQQVFDL
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VAGVTKQTLVPGVQNLLRAMIENGRLSALPEVAAQFHALVNASSGVSDAIVYSAFPIEPA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHH
ALADLVATLEKRFGRRLSATVQLEPELIGGVRVVVGDEVLDTSVKARLEHMKVALTA
HHHHHHHHHHHHHCCHHHHEEEECHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA