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The map label for this gene is lysN [H]

Identifier: 124265379

GI number: 124265379

Start: 202886

End: 204094

Strand: Direct

Name: lysN [H]

Synonym: Mpe_A0186

Alternate gene names: 124265379

Gene position: 202886-204094 (Clockwise)

Preceding gene: 124265378

Following gene: 124265380

Centisome position: 5.02

GC content: 74.52

Gene sequence:

>1209_bases
ATGACCTGGACCCTGGCGCGGCGCACCGAGCGCATGAATCCTTCCGCGATCCGCGAGATCCTGAAACTGGCCGAACGGCC
CGGCGTGCTGTCACTGGCCGGCGGCCTGCCGTCGCCGGACGGCTTCCCGGTCGAGGCGCTGCGCGAGGCCAGCGCCCGGG
TGCTGCGCGACACCCCACGGGAGGCGCTGCAGTACGCCGCGAGCGAAGGCTACGGGCCGCTGCGCGAGTGGGTCGCGGCC
CGGCTCGCCAACGACGGCGTCGTGGTCGAACCCGGGCAGGTGCTGGTCACCACCGGCTCGCAACAGGGGCTGGACCTGGT
CGGCAAGCTGCTGATCGATGCCGGCAGCGCGGTCGCGGTGGAGACGCCCACCTACCTGGGCGCGCTGCAGGCCTTCGCGC
CCTGCGAGCCGGCGTTCGCCGCGCTCGCCTCCGACGACGAGGGTCCGAAGCCCGAGGCCCTGGCCGGCGCCGCGGGCGCG
CGCTTCGCGTACCTGCTGCCGAACTTCCAGAACCCGACCGGGCGGGTGATCTCGGAGGCCCGTCGCGAGGCCCTGGTGGC
GGCGGCGCAGGCGGCTGCGCTGCCGCTGGTCGAGGACAACCCCTATGGCGAGCTGTGGTTCGACGCCCCGCCACCGGCGC
CGCTGGCCGCGCGCTGGCCGCAGGGCACGATCTACCTCGGCTCGTTCTCGAAGATCCTCGCGCCCGGCCTGCGGCTGGGG
TATGTGGTGGCGCCGCCGGCGCTGTATCCGAAGCTGCTGCAGGTCAAGCAGGCGGCCGACCTGCACACGCCGGGCTTCAA
CCAGCGCATCGTCCACGAGGTCGTGCGAGACGGCCTGCTCGATCGCCATGTGCCGACCGTGCGCGCGCGCCATGCCGCGC
AACGCGACGCGATGGCGGCGGCGCTGCGCGCGCACCTGCCCGCCGGCGCCGAATGGCAGCCACCGCGCGGCGGCATGTTC
TTCTGGCTGCGGCTGCCGCCGGGGCTGGACGCGACGGCGCTGCTGCCGCGCGCTATCGCCGCCGGCGTGGCCTACGTGCC
GGGTGCGCCCTTCCATGCCGGCGAAGCCGACCCGCGCACGCTGCGGCTGAGCTTCGTCACGCTGACGCCAGCGCAGCTGC
ACACTGCGATCGCCACGCTCGGGCGCGTGGTGCACGAGGCACTGGCCGAGCAGGCCGGGTCGGCGCTCTCGCTGAGGAGA
GCCGCATGA

Upstream 100 bases:

>100_bases
ATCCCGCCGCGCTGCCGCTGCCCGGCTTCGACAGCACGTGGCTGCATGTGCAGCAGGCGCTGGACTGGATGCTCGACGAC
ACCCCTCGAGGAGACCCCCG

Downstream 100 bases:

>100_bases
GCGCGAACCCCGCTCGCCGCTTCTCGCAGGTCGACGTGTTCACCGCCGAGCCGTTGCGCGGCAACGCCGTCGCGGTGGTG
TTCGACGCCGAGGGCCTGGA

Product: valine-pyruvate aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTWTLARRTERMNPSAIREILKLAERPGVLSLAGGLPSPDGFPVEALREASARVLRDTPREALQYAASEGYGPLREWVAA
RLANDGVVVEPGQVLVTTGSQQGLDLVGKLLIDAGSAVAVETPTYLGALQAFAPCEPAFAALASDDEGPKPEALAGAAGA
RFAYLLPNFQNPTGRVISEARREALVAAAQAAALPLVEDNPYGELWFDAPPPAPLAARWPQGTIYLGSFSKILAPGLRLG
YVVAPPALYPKLLQVKQAADLHTPGFNQRIVHEVVRDGLLDRHVPTVRARHAAQRDAMAAALRAHLPAGAEWQPPRGGMF
FWLRLPPGLDATALLPRAIAAGVAYVPGAPFHAGEADPRTLRLSFVTLTPAQLHTAIATLGRVVHEALAEQAGSALSLRR
AA

Sequences:

>Translated_402_residues
MTWTLARRTERMNPSAIREILKLAERPGVLSLAGGLPSPDGFPVEALREASARVLRDTPREALQYAASEGYGPLREWVAA
RLANDGVVVEPGQVLVTTGSQQGLDLVGKLLIDAGSAVAVETPTYLGALQAFAPCEPAFAALASDDEGPKPEALAGAAGA
RFAYLLPNFQNPTGRVISEARREALVAAAQAAALPLVEDNPYGELWFDAPPPAPLAARWPQGTIYLGSFSKILAPGLRLG
YVVAPPALYPKLLQVKQAADLHTPGFNQRIVHEVVRDGLLDRHVPTVRARHAAQRDAMAAALRAHLPAGAEWQPPRGGMF
FWLRLPPGLDATALLPRAIAAGVAYVPGAPFHAGEADPRTLRLSFVTLTPAQLHTAIATLGRVVHEALAEQAGSALSLRR
AA
>Mature_401_residues
TWTLARRTERMNPSAIREILKLAERPGVLSLAGGLPSPDGFPVEALREASARVLRDTPREALQYAASEGYGPLREWVAAR
LANDGVVVEPGQVLVTTGSQQGLDLVGKLLIDAGSAVAVETPTYLGALQAFAPCEPAFAALASDDEGPKPEALAGAAGAR
FAYLLPNFQNPTGRVISEARREALVAAAQAAALPLVEDNPYGELWFDAPPPAPLAARWPQGTIYLGSFSKILAPGLRLGY
VVAPPALYPKLLQVKQAADLHTPGFNQRIVHEVVRDGLLDRHVPTVRARHAAQRDAMAAALRAHLPAGAEWQPPRGGMFF
WLRLPPGLDATALLPRAIAAGVAYVPGAPFHAGEADPRTLRLSFVTLTPAQLHTAIATLGRVVHEALAEQAGSALSLRRA
A

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=412, Percent_Identity=31.0679611650485, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI33469970, Length=412, Percent_Identity=31.0679611650485, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI95147551, Length=338, Percent_Identity=26.3313609467456, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI169881279, Length=338, Percent_Identity=26.3313609467456, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1787710, Length=380, Percent_Identity=28.6842105263158, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790797, Length=393, Percent_Identity=25.6997455470738, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI48994949, Length=234, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321000, Length=373, Percent_Identity=24.9329758713137, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356535, Length=399, Percent_Identity=25.31328320802, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 42586; Mature: 42455

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWTLARRTERMNPSAIREILKLAERPGVLSLAGGLPSPDGFPVEALREASARVLRDTPR
CCCCHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHH
EALQYAASEGYGPLREWVAARLANDGVVVEPGQVLVTTGSQQGLDLVGKLLIDAGSAVAV
HHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCEEEEECCCCCCHHHHHHHHHCCCCEEEE
ETPTYLGALQAFAPCEPAFAALASDDEGPKPEALAGAAGARFAYLLPNFQNPTGRVISEA
ECCHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCCCCHHHHHHHH
RREALVAAAQAAALPLVEDNPYGELWFDAPPPAPLAARWPQGTIYLGSFSKILAPGLRLG
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCC
YVVAPPALYPKLLQVKQAADLHTPGFNQRIVHEVVRDGLLDRHVPTVRARHAAQRDAMAA
EEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHH
ALRAHLPAGAEWQPPRGGMFFWLRLPPGLDATALLPRAIAAGVAYVPGAPFHAGEADPRT
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCE
LRLSFVTLTPAQLHTAIATLGRVVHEALAEQAGSALSLRRAA
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
TWTLARRTERMNPSAIREILKLAERPGVLSLAGGLPSPDGFPVEALREASARVLRDTPR
CCCHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHH
EALQYAASEGYGPLREWVAARLANDGVVVEPGQVLVTTGSQQGLDLVGKLLIDAGSAVAV
HHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCEEEEECCCCCCHHHHHHHHHCCCCEEEE
ETPTYLGALQAFAPCEPAFAALASDDEGPKPEALAGAAGARFAYLLPNFQNPTGRVISEA
ECCHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCCCCHHHHHHHH
RREALVAAAQAAALPLVEDNPYGELWFDAPPPAPLAARWPQGTIYLGSFSKILAPGLRLG
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCC
YVVAPPALYPKLLQVKQAADLHTPGFNQRIVHEVVRDGLLDRHVPTVRARHAAQRDAMAA
EEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHH
ALRAHLPAGAEWQPPRGGMFFWLRLPPGLDATALLPRAIAAGVAYVPGAPFHAGEADPRT
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCE
LRLSFVTLTPAQLHTAIATLGRVVHEALAEQAGSALSLRRAA
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA