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The map label for this gene is ahpC [C]

Identifier: 124265314

GI number: 124265314

Start: 123711

End: 124355

Strand: Direct

Name: ahpC [C]

Synonym: Mpe_A0121

Alternate gene names: 124265314

Gene position: 123711-124355 (Clockwise)

Preceding gene: 124265313

Following gene: 124265315

Centisome position: 3.06

GC content: 65.27

Gene sequence:

>645_bases
ATGCCAAGCCTGAGACTCGGCGACATCGCCCCCGATTTCGAGCAACAGTCCACCCAGGGTCCGCTCCAGTTCCACGCGTG
GCTCGGCGACAGCTGGGGCGTGCTGTTCTCTCACCCGGCCGACTTCACGCCCGTCTGCACCACCGAGCTCGGATTGACGG
CCCGCCTCAAGGCCGAGTTCTCCAAGCGCAATGTCAAGGTGATTGCGCTGTCGGTCGACCCGGTCGACAAGCACGGCGCG
TGGATCGAGGACATCAACCGCACCCAGAACGCGGTGGTCGACTTCCCGATCCTGGCCGACGCCGACCGCAAGGTCAGCGA
GCTCTACGACCTGATCCATCCGAACGCCAGCACGACCGCCACGGTGCGCTCGCTGTTCGTCATCGACCCGGCGAAGAAGA
TCCGCCTGACGATCACCTACCCGGCCTCGACCGGGCGCAATTTCGACGAGATCCTGCGCGTCATCGATTCGCTGCAGCTG
ACCGAATACCACAGCGTCGCGACGCCGGCGAACTGGAAGGACGGCGACGACGTGGTGATCGTGCCCGCGCTGCAGGACGC
CGAACTGATCCGGCAGAAGTTTCCGAAGGGCTATACCGCCGTCACGCCCTATCTGCGCCTGACGCCGCAGCCCAATCGCG
CCTGA

Upstream 100 bases:

>100_bases
CGCTGGCCGAGTGGTCGTTCGCGGTCCGAGGGGCGGCACACCGCCGCGGGTCGTCCTTCCTCCTCGATTCCCTGCCTCCA
TCCCATCCAGGAGCTCCACC

Downstream 100 bases:

>100_bases
GACTTCTTCGAGAAACGCATAAGCGTCCTTGCTTTCATTCGTTCCGCGTTGAAGCGGCGCTTTCTAGCATCTCCCCATTC
GCTCATTCCCGCCCTGATTC

Product: 1-Cys peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MPSLRLGDIAPDFEQQSTQGPLQFHAWLGDSWGVLFSHPADFTPVCTTELGLTARLKAEFSKRNVKVIALSVDPVDKHGA
WIEDINRTQNAVVDFPILADADRKVSELYDLIHPNASTTATVRSLFVIDPAKKIRLTITYPASTGRNFDEILRVIDSLQL
TEYHSVATPANWKDGDDVVIVPALQDAELIRQKFPKGYTAVTPYLRLTPQPNRA

Sequences:

>Translated_214_residues
MPSLRLGDIAPDFEQQSTQGPLQFHAWLGDSWGVLFSHPADFTPVCTTELGLTARLKAEFSKRNVKVIALSVDPVDKHGA
WIEDINRTQNAVVDFPILADADRKVSELYDLIHPNASTTATVRSLFVIDPAKKIRLTITYPASTGRNFDEILRVIDSLQL
TEYHSVATPANWKDGDDVVIVPALQDAELIRQKFPKGYTAVTPYLRLTPQPNRA
>Mature_213_residues
PSLRLGDIAPDFEQQSTQGPLQFHAWLGDSWGVLFSHPADFTPVCTTELGLTARLKAEFSKRNVKVIALSVDPVDKHGAW
IEDINRTQNAVVDFPILADADRKVSELYDLIHPNASTTATVRSLFVIDPAKKIRLTITYPASTGRNFDEILRVIDSLQLT
EYHSVATPANWKDGDDVVIVPALQDAELIRQKFPKGYTAVTPYLRLTPQPNRA

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=225, Percent_Identity=52, Blast_Score=220, Evalue=6e-58,
Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=32.1052631578947, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=32.1052631578947, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=32.1052631578947, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI5453549, Length=149, Percent_Identity=34.2281879194631, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI32483377, Length=140, Percent_Identity=32.8571428571429, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI5802974, Length=140, Percent_Identity=32.8571428571429, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=31.1688311688312, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=199, Percent_Identity=39.6984924623116, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI193204376, Length=197, Percent_Identity=31.4720812182741, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32565831, Length=197, Percent_Identity=31.4720812182741, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554494, Length=166, Percent_Identity=30.7228915662651, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319407, Length=214, Percent_Identity=51.4018691588785, Blast_Score=216, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6323613, Length=157, Percent_Identity=29.9363057324841, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=157, Percent_Identity=29.2993630573248, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=48.4018264840183, Blast_Score=208, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24652434, Length=210, Percent_Identity=47.6190476190476, Blast_Score=190, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24652436, Length=210, Percent_Identity=47.6190476190476, Blast_Score=190, Evalue=5e-49,
Organism=Drosophila melanogaster, GI17975518, Length=210, Percent_Identity=47.6190476190476, Blast_Score=190, Evalue=7e-49,
Organism=Drosophila melanogaster, GI17157991, Length=157, Percent_Identity=35.031847133758, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641739, Length=157, Percent_Identity=35.031847133758, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17738015, Length=195, Percent_Identity=31.2820512820513, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656348, Length=177, Percent_Identity=32.7683615819209, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17864676, Length=177, Percent_Identity=32.7683615819209, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357347, Length=196, Percent_Identity=28.0612244897959, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23821; Mature: 23690

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLRLGDIAPDFEQQSTQGPLQFHAWLGDSWGVLFSHPADFTPVCTTELGLTARLKAEF
CCCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCEEEECCCCCCCEEECCCCCEEEEEEHH
SKRNVKVIALSVDPVDKHGAWIEDINRTQNAVVDFPILADADRKVSELYDLIHPNASTTA
CCCCEEEEEEEECCCCCCCCHHHHHHCCCCEEEECCEECCCCHHHHHHHHHHCCCCCCHH
TVRSLFVIDPAKKIRLTITYPASTGRNFDEILRVIDSLQLTEYHSVATPANWKDGDDVVI
EEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VPALQDAELIRQKFPKGYTAVTPYLRLTPQPNRA
EECCCCHHHHHHHCCCCCEEECCEEEECCCCCCC
>Mature Secondary Structure 
PSLRLGDIAPDFEQQSTQGPLQFHAWLGDSWGVLFSHPADFTPVCTTELGLTARLKAEF
CCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCEEEECCCCCCCEEECCCCCEEEEEEHH
SKRNVKVIALSVDPVDKHGAWIEDINRTQNAVVDFPILADADRKVSELYDLIHPNASTTA
CCCCEEEEEEEECCCCCCCCHHHHHHCCCCEEEECCEECCCCHHHHHHHHHHCCCCCCHH
TVRSLFVIDPAKKIRLTITYPASTGRNFDEILRVIDSLQLTEYHSVATPANWKDGDDVVI
EEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VPALQDAELIRQKFPKGYTAVTPYLRLTPQPNRA
EECCCCHHHHHHHCCCCCEEECCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]