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The map label for this gene is gluQ

Identifier: 124022282

GI number: 124022282

Start: 551489

End: 552409

Strand: Direct

Name: gluQ

Synonym: P9303_05721

Alternate gene names: 124022282

Gene position: 551489-552409 (Clockwise)

Preceding gene: 124022281

Following gene: 124022283

Centisome position: 20.56

GC content: 57.0

Gene sequence:

>921_bases
ATGGCCACGTCCTCTGAACTGCCTGATCATCTGTATGAGCAGATGGAAGCGGGGCAGCGCCTTAGGAATCAGGGCTATCG
CGGCAGGTTTGCCCCGTCTCCGACGGGACCATTACACCTGGGCAATCTGTGCACTGCTCTGGTGTCTTGGTTGCAAGCGC
GCTTGGCTAATGGGGCTTGGCTGTTGCGGGTGGATGACCTGGATCAGCCTCGCAATCGTGTGGGAGCGGTTGAGAGCCTG
CAGCAGGATTTGCACTGGCTAGGCCTTGATTGGGATGGTCCCGTGGTGTTTCAGAGCCGCCGCCGTGGGCTTTACAACTC
TTTCCTCTCCGCTCTGCGGCGCCAGGGGAAGTTGTATGCCTGTCGATGTAGCCGGCGAATGTTGGCTGACATCTCAGCAC
CAGCTGGGCGGCACTTGGTTTACCCAGGCACGTGTCGAGATCTGGAGCTGTTTTGGGGGTGGCATGAGGGCAGGCTGCCC
AGTTGGCGTTTAAGGGTGAGCAAAGAGTTCTCCCATACCAGTGGGGACGTGATTTTGCGGCGCGCTGATGGTTTTATCGC
TTATCACTTGGCGACGGTTGTTGATGAACTGACTCTCGGGATTAGTGAGGTCGTACGCGGTGAAGACTTGCTTGTGGCCA
TGAATGCACAGCTCGCTTTGATCAATGAGATTTCAGCGCGGCCTGTGATCTATCGCCACGTGCCGTTGTTGTGTGATGAC
CAAGGCAGGAAGTTGGCCAAGCGAGAGGGACATGCTGGTTTGGACAGCCTGCGTTCCGAGGGACTGGGGCCTTCCCATGT
GGTGGGCTGGCTTGCTGCTAGCCAGAGCCTTGTTCCTTTTGGTGCTGAACTCACGGCAGGGGAGTTGTTGAGTGAGTTGA
AGAAGAAGGAGGGGGTTCTAAAAAGCGTGCTGAAGCCTTAA

Upstream 100 bases:

>100_bases
GTTCAGGGCTGATTTTTTAGCCCTTGTTTGCAGACGGGCGGTCGTCACGGCCGCCTTTTATTTGTGGGCCTACTGAGTCA
GGGCTCCTTCCATTGATTCA

Downstream 100 bases:

>100_bases
AGGCGCAATGGCTCTAATTCTTAACGAAGCCTTCGGGATCGTAATCGCAAAAATGTATGAAAATAACTGGTCACTTAATG
CACACAATCAATGTCGATCT

Product: glutamyl/glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glu-Q-RSs

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MATSSELPDHLYEQMEAGQRLRNQGYRGRFAPSPTGPLHLGNLCTALVSWLQARLANGAWLLRVDDLDQPRNRVGAVESL
QQDLHWLGLDWDGPVVFQSRRRGLYNSFLSALRRQGKLYACRCSRRMLADISAPAGRHLVYPGTCRDLELFWGWHEGRLP
SWRLRVSKEFSHTSGDVILRRADGFIAYHLATVVDELTLGISEVVRGEDLLVAMNAQLALINEISARPVIYRHVPLLCDD
QGRKLAKREGHAGLDSLRSEGLGPSHVVGWLAASQSLVPFGAELTAGELLSELKKKEGVLKSVLKP

Sequences:

>Translated_306_residues
MATSSELPDHLYEQMEAGQRLRNQGYRGRFAPSPTGPLHLGNLCTALVSWLQARLANGAWLLRVDDLDQPRNRVGAVESL
QQDLHWLGLDWDGPVVFQSRRRGLYNSFLSALRRQGKLYACRCSRRMLADISAPAGRHLVYPGTCRDLELFWGWHEGRLP
SWRLRVSKEFSHTSGDVILRRADGFIAYHLATVVDELTLGISEVVRGEDLLVAMNAQLALINEISARPVIYRHVPLLCDD
QGRKLAKREGHAGLDSLRSEGLGPSHVVGWLAASQSLVPFGAELTAGELLSELKKKEGVLKSVLKP
>Mature_305_residues
ATSSELPDHLYEQMEAGQRLRNQGYRGRFAPSPTGPLHLGNLCTALVSWLQARLANGAWLLRVDDLDQPRNRVGAVESLQ
QDLHWLGLDWDGPVVFQSRRRGLYNSFLSALRRQGKLYACRCSRRMLADISAPAGRHLVYPGTCRDLELFWGWHEGRLPS
WRLRVSKEFSHTSGDVILRRADGFIAYHLATVVDELTLGISEVVRGEDLLVAMNAQLALINEISARPVIYRHVPLLCDDQ
GRKLAKREGHAGLDSLRSEGLGPSHVVGWLAASQSLVPFGAELTAGELLSELKKKEGVLKSVLKP

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily

Homologues:

Organism=Homo sapiens, GI134288884, Length=296, Percent_Identity=33.445945945946, Blast_Score=139, Evalue=2e-33,
Organism=Escherichia coli, GI226510925, Length=260, Percent_Identity=36.5384615384615, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1788743, Length=261, Percent_Identity=32.9501915708812, Blast_Score=146, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324540, Length=274, Percent_Identity=33.5766423357664, Blast_Score=141, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24665321, Length=278, Percent_Identity=34.1726618705036, Blast_Score=140, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLUQ_PROM3 (A2C764)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016589.1
- ProteinModelPortal:   A2C764
- SMR:   A2C764
- STRING:   A2C764
- GeneID:   4778302
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_05721
- eggNOG:   COG0008
- HOGENOM:   HBG628189
- OMA:   DAPSSYH
- ProtClustDB:   PRK05710
- GO:   GO:0005737
- HAMAP:   MF_01428
- InterPro:   IPR001412
- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119
- PRINTS:   PR00987

Pfam domain/function: PF00749 tRNA-synt_1c

EC number: NA

Molecular weight: Translated: 34071; Mature: 33939

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 65-65 BINDING 188-188 BINDING 206-206 BINDING 247-247

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSSELPDHLYEQMEAGQRLRNQGYRGRFAPSPTGPLHLGNLCTALVSWLQARLANGAW
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
LLRVDDLDQPRNRVGAVESLQQDLHWLGLDWDGPVVFQSRRRGLYNSFLSALRRQGKLYA
EEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHCHHHHHHHHHHHHCCCEEE
CRCSRRMLADISAPAGRHLVYPGTCRDLELFWGWHEGRLPSWRLRVSKEFSHTSGDVILR
EHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCEEEEEHHCCCCCCCEEEE
RADGFIAYHLATVVDELTLGISEVVRGEDLLVAMNAQLALINEISARPVIYRHVPLLCDD
ECCCHHHHHHHHHHHHHHHCHHHHHCCCCEEEEECCCEEEEHHHCCCCEEEECCCEEECC
QGRKLAKREGHAGLDSLRSEGLGPSHVVGWLAASQSLVPFGAELTAGELLSELKKKEGVL
CCHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KSVLKP
HHHHCC
>Mature Secondary Structure 
ATSSELPDHLYEQMEAGQRLRNQGYRGRFAPSPTGPLHLGNLCTALVSWLQARLANGAW
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
LLRVDDLDQPRNRVGAVESLQQDLHWLGLDWDGPVVFQSRRRGLYNSFLSALRRQGKLYA
EEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHCHHHHHHHHHHHHCCCEEE
CRCSRRMLADISAPAGRHLVYPGTCRDLELFWGWHEGRLPSWRLRVSKEFSHTSGDVILR
EHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCEEEEEHHCCCCCCCEEEE
RADGFIAYHLATVVDELTLGISEVVRGEDLLVAMNAQLALINEISARPVIYRHVPLLCDD
ECCCHHHHHHHHHHHHHHHCHHHHHCCCCEEEEECCCEEEEHHHCCCCEEEECCCEEECC
QGRKLAKREGHAGLDSLRSEGLGPSHVVGWLAASQSLVPFGAELTAGELLSELKKKEGVL
CCHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KSVLKP
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA