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The map label for this gene is tldD [C]

Identifier: 124025753

GI number: 124025753

Start: 963463

End: 964872

Strand: Direct

Name: tldD [C]

Synonym: NATL1_10461

Alternate gene names: 124025753

Gene position: 963463-964872 (Clockwise)

Preceding gene: 124025752

Following gene: 124025754

Centisome position: 51.67

GC content: 37.3

Gene sequence:

>1410_bases
TTGCTATTCCATACTTTTGACGACAAATTAAAACCTCAAGTTGAAGAATTATTGTCTCTGGGCAAATCCGCTGGGGCTGA
CCTAGTAGAAGTCTTTCTTGAAAAATCAGACAACATATCTCTCTTAGCCGAGCAGGATGACATTTCAAATGTAAGTCCAT
CTTTCGGGATTGGAGCAGGTATTAGGGTGTTTCTTGGCAAAAAAGATGGTTTTGTAAGCACAAATGATTTATCAAAAGCA
GGACTTCTCTTTGCCTTAAATCAAGCATTAGGAATGTTAGGCCTCACAAGTGGTTCAAATAATAAAGACAAGTTTGAAGG
GTTAAAGAAATTAAAGGATTTTGGATCAAATAAGAAAGATTGGTTAGATCATTCACCAGATCTCAATGAATCCACTCTTA
AACTGCTTGAAGCCACTAACTCACTGGCAGATAAAAATAAAAATCTTCAAGTAAGAAGAGCGAGTTATTCACGGAATTGG
CAAGAAGTTTTAGTTGCAGCTTCAGACGGTGTATTTTCAAGAGATATCCGTCTTCATCAAACTGTTGGTATAAATGTAAT
TGCCCAAAAAGATAAACATAGATCGACCTCTGCTAGAAGATATGGAAGTTCTGGTAATCCTGACGATTTAAGAAACTGGG
ATATCGAAAAAAGTGCTTGTGAATTAAATGAAAGTGCTCAGAAAATGCTTTACGCAGAATTTGTTGAAGCTGGCCAAATG
CCTGTAGTTCTTGCTAACAAATTTGGAGGAGTCATATTCCATGAAGCTTGTGGTCATCTTCTTGAAACAACTCAATTAGA
AAGAGGAACATCTCCATTTCATGACTCAATAAATAAGCAAATTGCTAACGAAGCCGTAAGTGCAGTTGATGAAGGACTTT
CGAATCATGCTTTTGGTTCACTCTCAATGGATGATGAAGGAATGGAACCTCAAAATACTTTATTAATTGAGAATGGGATA
TTAAAAAAGTTTCTTTCGGATAGAGCGGGCTCTCTAAGAACTGGTCATCCAAGAACAGGTAGTGGAAGGAGGCAAAATTT
CTCTTTCGCTGCTGCAAGTCGTATGAGAAATACATACATTAAGCAAGGTAATTTTTCGCCAGTAGAATTAATTAAAAGTG
TTGACGATGGTCTTTATTGTAAATCAATGGGCGGTGGCAGTGTAGGACCAACTGGTCAGTTTAACTTCTCTGTTGAAGAA
GGCTATTTAATAAAAAATGGAAAGCTTGATAAACCAGTTAAAGGGGCAACATTAATAGGTGAAGCAAAAGAAATACTACC
TAGAATTTCAATGTGCGCAAACGATTTAGATCTTGCACCAGGCTTCTGCGGGTCTGTAAGTGGAAGTGTGAATGTTACTG
TCGGCCAACCACATATAAAAGTAGATTCAATAACAGTTGGAGGTAGATAA

Upstream 100 bases:

>100_bases
ATGTCCTATTAATATTAATTACGCAGTTAAGCCAATCAAATGCCATAATGTAAAAAAAAAAAAATTGACTAATTCATTAC
TAACTAAAGAAAGTGAAAAT

Downstream 100 bases:

>100_bases
TATGAATAAATCAATCACTGATTCTAAAACAAGTGAATTAGATCCAATTATATTAAATAATCTTTTAAAAAAATATAGTG
AAGAGTCATCTATAAATAAA

Product: putative modulator of DNA gyrase; TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MLFHTFDDKLKPQVEELLSLGKSAGADLVEVFLEKSDNISLLAEQDDISNVSPSFGIGAGIRVFLGKKDGFVSTNDLSKA
GLLFALNQALGMLGLTSGSNNKDKFEGLKKLKDFGSNKKDWLDHSPDLNESTLKLLEATNSLADKNKNLQVRRASYSRNW
QEVLVAASDGVFSRDIRLHQTVGINVIAQKDKHRSTSARRYGSSGNPDDLRNWDIEKSACELNESAQKMLYAEFVEAGQM
PVVLANKFGGVIFHEACGHLLETTQLERGTSPFHDSINKQIANEAVSAVDEGLSNHAFGSLSMDDEGMEPQNTLLIENGI
LKKFLSDRAGSLRTGHPRTGSGRRQNFSFAAASRMRNTYIKQGNFSPVELIKSVDDGLYCKSMGGGSVGPTGQFNFSVEE
GYLIKNGKLDKPVKGATLIGEAKEILPRISMCANDLDLAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR

Sequences:

>Translated_469_residues
MLFHTFDDKLKPQVEELLSLGKSAGADLVEVFLEKSDNISLLAEQDDISNVSPSFGIGAGIRVFLGKKDGFVSTNDLSKA
GLLFALNQALGMLGLTSGSNNKDKFEGLKKLKDFGSNKKDWLDHSPDLNESTLKLLEATNSLADKNKNLQVRRASYSRNW
QEVLVAASDGVFSRDIRLHQTVGINVIAQKDKHRSTSARRYGSSGNPDDLRNWDIEKSACELNESAQKMLYAEFVEAGQM
PVVLANKFGGVIFHEACGHLLETTQLERGTSPFHDSINKQIANEAVSAVDEGLSNHAFGSLSMDDEGMEPQNTLLIENGI
LKKFLSDRAGSLRTGHPRTGSGRRQNFSFAAASRMRNTYIKQGNFSPVELIKSVDDGLYCKSMGGGSVGPTGQFNFSVEE
GYLIKNGKLDKPVKGATLIGEAKEILPRISMCANDLDLAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR
>Mature_469_residues
MLFHTFDDKLKPQVEELLSLGKSAGADLVEVFLEKSDNISLLAEQDDISNVSPSFGIGAGIRVFLGKKDGFVSTNDLSKA
GLLFALNQALGMLGLTSGSNNKDKFEGLKKLKDFGSNKKDWLDHSPDLNESTLKLLEATNSLADKNKNLQVRRASYSRNW
QEVLVAASDGVFSRDIRLHQTVGINVIAQKDKHRSTSARRYGSSGNPDDLRNWDIEKSACELNESAQKMLYAEFVEAGQM
PVVLANKFGGVIFHEACGHLLETTQLERGTSPFHDSINKQIANEAVSAVDEGLSNHAFGSLSMDDEGMEPQNTLLIENGI
LKKFLSDRAGSLRTGHPRTGSGRRQNFSFAAASRMRNTYIKQGNFSPVELIKSVDDGLYCKSMGGGSVGPTGQFNFSVEE
GYLIKNGKLDKPVKGATLIGEAKEILPRISMCANDLDLAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=456, Percent_Identity=36.1842105263158, Blast_Score=233, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50807; Mature: 50807

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFHTFDDKLKPQVEELLSLGKSAGADLVEVFLEKSDNISLLAEQDDISNVSPSFGIGAG
CCCCCCCHHCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
IRVFLGKKDGFVSTNDLSKAGLLFALNQALGMLGLTSGSNNKDKFEGLKKLKDFGSNKKD
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCHH
WLDHSPDLNESTLKLLEATNSLADKNKNLQVRRASYSRNWQEVLVAASDGVFSRDIRLHQ
HCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECHHCCCHHHEEEECCCCCEECCEEEEE
TVGINVIAQKDKHRSTSARRYGSSGNPDDLRNWDIEKSACELNESAQKMLYAEFVEAGQM
EECEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PVVLANKFGGVIFHEACGHLLETTQLERGTSPFHDSINKQIANEAVSAVDEGLSNHAFGS
CEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCC
LSMDDEGMEPQNTLLIENGILKKFLSDRAGSLRTGHPRTGSGRRQNFSFAAASRMRNTYI
CCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KQGNFSPVELIKSVDDGLYCKSMGGGSVGPTGQFNFSVEEGYLIKNGKLDKPVKGATLIG
CCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCHHH
EAKEILPRISMCANDLDLAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEECCCC
>Mature Secondary Structure
MLFHTFDDKLKPQVEELLSLGKSAGADLVEVFLEKSDNISLLAEQDDISNVSPSFGIGAG
CCCCCCCHHCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
IRVFLGKKDGFVSTNDLSKAGLLFALNQALGMLGLTSGSNNKDKFEGLKKLKDFGSNKKD
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCHH
WLDHSPDLNESTLKLLEATNSLADKNKNLQVRRASYSRNWQEVLVAASDGVFSRDIRLHQ
HCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECHHCCCHHHEEEECCCCCEECCEEEEE
TVGINVIAQKDKHRSTSARRYGSSGNPDDLRNWDIEKSACELNESAQKMLYAEFVEAGQM
EECEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PVVLANKFGGVIFHEACGHLLETTQLERGTSPFHDSINKQIANEAVSAVDEGLSNHAFGS
CEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCC
LSMDDEGMEPQNTLLIENGILKKFLSDRAGSLRTGHPRTGSGRRQNFSFAAASRMRNTYI
CCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KQGNFSPVELIKSVDDGLYCKSMGGGSVGPTGQFNFSVEEGYLIKNGKLDKPVKGATLIG
CCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCHHH
EAKEILPRISMCANDLDLAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]