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The map label for this gene is pmbA [H]

Identifier: 124025754

GI number: 124025754

Start: 964874

End: 966262

Strand: Direct

Name: pmbA [H]

Synonym: NATL1_10471

Alternate gene names: 124025754

Gene position: 964874-966262 (Clockwise)

Preceding gene: 124025753

Following gene: 124025755

Centisome position: 51.74

GC content: 33.05

Gene sequence:

>1389_bases
ATGAATAAATCAATCACTGATTCTAAAACAAGTGAATTAGATCCAATTATATTAAATAATCTTTTAAAAAAATATAGTGA
AGAGTCATCTATAAATAAATGGGATATGGGCGCATCATCCAGTAGGGATATATCTGTTCAAGTTCAGCAAGGAAATGCTA
AACAACTAAAAGGTTCCCAAAGAAATTCCATGACATTAAGAGTATGGAATAAAAACAATCAAGTAGGAATTACTAGTACA
TCCGATTTGTCGAGTGAAGGCATTAAAAAAGCAATGAAAGGAGCAATTGAAGCTAGCCTATTTGGTAATGAAAAGGAGTC
TCCTGAATTTTCCTCATTAGCTAAATCAGAATTAGAAGATATTAATCCTAAAATATCTAATTCCCATACAATTGATCAAT
TGCTTAGTATTTTAAAGAAGGCAGAAAAAGAATTAATAGATACTCATAAATCAATAGATTCTGTTCCTTACAATGGTTTA
AATGAAAGTTATATGGAAAGAATATATATAAATAGTGAAGGTGCTAAAAGACATATGAAATTATCACAATCTTCTATATA
TTTGTATGCCAAGGCTGAGGAACAAAATAAAAAGCCTAGAAGTGCAGGGGGGATAAGAATGAACTCTAATTTAGAAGAAC
TTGATATTGATTCATGTATAAGTGAAACATCTGATAAGTTAATTAGTCATTTAGATTATAAATCAATAGAAACAAACAAG
TATCTTGTTTGTTTTACTCCTGAGGCTTTTCTTCAACTAATAAGTGCATTTAGTTCTATGTTTAATGCACGGTCTATTAT
TGATGGACTAAGTTTAATGAAAGAAGACTCACTAGGTAATCAAATTTCAGTTCCAAATTTAAACATAAGCGACGAAGGTC
TTCATCCTAAAAATGTTGGAGCTTTTAGTTTTGATGGTGAAGGAACACCCACACAAAATATCCAATTGGTCACAAACGGA
ATTTTGACACAACTTCTTCATTCAGAGGCAACTGCAAGGAAATTTGGTGTTAAACCTACAGGGCATGCAGGCTTAGGCGC
TAAGGTATCCGTTTCTCCAGATTGGCTAGTCATAAGCAAAAGTGAATCTGAAATGGATAAAGATGAAAGCCTAAGCATTG
AAAATACAATCAAAGAATACATATTGATAGATGAACTATCTGCGATTCATTCTGGAGTCAAGGCTAGTCAAGGCTCCTTC
TCCTTGCCCTTTGATGGATGGATAGTTAATGATGGGAAGAAGACATCAATTGAAGCCGCTACAGTTGCTGGAGATATTTT
AAAAGTTTTATCAAGTATTGTAAAAATTGAAGATGAACAGATAGTTACACATCAAGGCATCAGCCCACATGTTTGGGTTG
AGAACATTTCAATTACTGGGGAAGCGTGA

Upstream 100 bases:

>100_bases
CTTGCACCAGGCTTCTGCGGGTCTGTAAGTGGAAGTGTGAATGTTACTGTCGGCCAACCACATATAAAAGTAGATTCAAT
AACAGTTGGAGGTAGATAAT

Downstream 100 bases:

>100_bases
AGATTGTTTTTTGGGGAACGCCTAAATATGCCGCAGAAAATTTAAGAACCATCGTTAAGGCCGGCTACGAAGTTATAGCT
GTAGTTACACAACCAGACAG

Product: putative modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNKSITDSKTSELDPIILNNLLKKYSEESSINKWDMGASSSRDISVQVQQGNAKQLKGSQRNSMTLRVWNKNNQVGITST
SDLSSEGIKKAMKGAIEASLFGNEKESPEFSSLAKSELEDINPKISNSHTIDQLLSILKKAEKELIDTHKSIDSVPYNGL
NESYMERIYINSEGAKRHMKLSQSSIYLYAKAEEQNKKPRSAGGIRMNSNLEELDIDSCISETSDKLISHLDYKSIETNK
YLVCFTPEAFLQLISAFSSMFNARSIIDGLSLMKEDSLGNQISVPNLNISDEGLHPKNVGAFSFDGEGTPTQNIQLVTNG
ILTQLLHSEATARKFGVKPTGHAGLGAKVSVSPDWLVISKSESEMDKDESLSIENTIKEYILIDELSAIHSGVKASQGSF
SLPFDGWIVNDGKKTSIEAATVAGDILKVLSSIVKIEDEQIVTHQGISPHVWVENISITGEA

Sequences:

>Translated_462_residues
MNKSITDSKTSELDPIILNNLLKKYSEESSINKWDMGASSSRDISVQVQQGNAKQLKGSQRNSMTLRVWNKNNQVGITST
SDLSSEGIKKAMKGAIEASLFGNEKESPEFSSLAKSELEDINPKISNSHTIDQLLSILKKAEKELIDTHKSIDSVPYNGL
NESYMERIYINSEGAKRHMKLSQSSIYLYAKAEEQNKKPRSAGGIRMNSNLEELDIDSCISETSDKLISHLDYKSIETNK
YLVCFTPEAFLQLISAFSSMFNARSIIDGLSLMKEDSLGNQISVPNLNISDEGLHPKNVGAFSFDGEGTPTQNIQLVTNG
ILTQLLHSEATARKFGVKPTGHAGLGAKVSVSPDWLVISKSESEMDKDESLSIENTIKEYILIDELSAIHSGVKASQGSF
SLPFDGWIVNDGKKTSIEAATVAGDILKVLSSIVKIEDEQIVTHQGISPHVWVENISITGEA
>Mature_462_residues
MNKSITDSKTSELDPIILNNLLKKYSEESSINKWDMGASSSRDISVQVQQGNAKQLKGSQRNSMTLRVWNKNNQVGITST
SDLSSEGIKKAMKGAIEASLFGNEKESPEFSSLAKSELEDINPKISNSHTIDQLLSILKKAEKELIDTHKSIDSVPYNGL
NESYMERIYINSEGAKRHMKLSQSSIYLYAKAEEQNKKPRSAGGIRMNSNLEELDIDSCISETSDKLISHLDYKSIETNK
YLVCFTPEAFLQLISAFSSMFNARSIIDGLSLMKEDSLGNQISVPNLNISDEGLHPKNVGAFSFDGEGTPTQNIQLVTNG
ILTQLLHSEATARKFGVKPTGHAGLGAKVSVSPDWLVISKSESEMDKDESLSIENTIKEYILIDELSAIHSGVKASQGSF
SLPFDGWIVNDGKKTSIEAATVAGDILKVLSSIVKIEDEQIVTHQGISPHVWVENISITGEA

Specific function: May facilitate the secretion of the peptide antibiotic microcin B17 (MccB17) by completing its maturation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=419, Percent_Identity=23.8663484486874, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50651; Mature: 50651

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00047 HISTONE_H4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSITDSKTSELDPIILNNLLKKYSEESSINKWDMGASSSRDISVQVQQGNAKQLKGSQ
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCC
RNSMTLRVWNKNNQVGITSTSDLSSEGIKKAMKGAIEASLFGNEKESPEFSSLAKSELED
CCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
INPKISNSHTIDQLLSILKKAEKELIDTHKSIDSVPYNGLNESYMERIYINSEGAKRHMK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEECCCCCHHHHE
LSQSSIYLYAKAEEQNKKPRSAGGIRMNSNLEELDIDSCISETSDKLISHLDYKSIETNK
ECCCEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YLVCFTPEAFLQLISAFSSMFNARSIIDGLSLMKEDSLGNQISVPNLNISDEGLHPKNVG
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCC
AFSFDGEGTPTQNIQLVTNGILTQLLHSEATARKFGVKPTGHAGLGAKVSVSPDWLVISK
EEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEC
SESEMDKDESLSIENTIKEYILIDELSAIHSGVKASQGSFSLPFDGWIVNDGKKTSIEAA
CHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEECCCCCCCCHHH
TVAGDILKVLSSIVKIEDEQIVTHQGISPHVWVENISITGEA
HHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEEEEECCC
>Mature Secondary Structure
MNKSITDSKTSELDPIILNNLLKKYSEESSINKWDMGASSSRDISVQVQQGNAKQLKGSQ
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCC
RNSMTLRVWNKNNQVGITSTSDLSSEGIKKAMKGAIEASLFGNEKESPEFSSLAKSELED
CCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
INPKISNSHTIDQLLSILKKAEKELIDTHKSIDSVPYNGLNESYMERIYINSEGAKRHMK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEECCCCCHHHHE
LSQSSIYLYAKAEEQNKKPRSAGGIRMNSNLEELDIDSCISETSDKLISHLDYKSIETNK
ECCCEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YLVCFTPEAFLQLISAFSSMFNARSIIDGLSLMKEDSLGNQISVPNLNISDEGLHPKNVG
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCC
AFSFDGEGTPTQNIQLVTNGILTQLLHSEATARKFGVKPTGHAGLGAKVSVSPDWLVISK
EEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEC
SESEMDKDESLSIENTIKEYILIDELSAIHSGVKASQGSFSLPFDGWIVNDGKKTSIEAA
CHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEECCCCCCCCHHH
TVAGDILKVLSSIVKIEDEQIVTHQGISPHVWVENISITGEA
HHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]