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The map label for this gene is murQ

Identifier: 124025695

GI number: 124025695

Start: 906972

End: 907904

Strand: Direct

Name: murQ

Synonym: NATL1_09881

Alternate gene names: 124025695

Gene position: 906972-907904 (Clockwise)

Preceding gene: 124025694

Following gene: 124025696

Centisome position: 48.64

GC content: 32.05

Gene sequence:

>933_bases
ATGAGTGATACAAATAATCATTCAAAAAATATTATTCATCGAATACTAACAGAGCAGATTAATTTAACTTCGAATGAATT
GGATACAAAGTCTACTAAAGAAATAGTTAATATTTTTTCTGAAGCTGATAAAGAACCTCAAAAAGCTGTTGAGCGTGTTA
TCCCAGAATTAATTAATGCTATTGATGAAATCACTGCAAGACTAAAATCAAAGGGTAGATTGTTTTATATAGGTGCAGGT
ACTTCAGGAAGATTAGGTGTACTTGATGCTTCTGAATGTCCCCCAACTTTTTGCTCGAATCCTGATTTGGTGCAAGGAAT
AATTGCTGGAGGCATACCTTCGCTAACAAGAAGTTCAGAACATCTTGAGGATGTATCTGAGATTGCTATCGCTGATCTTA
AAGATAGAAATTTCTCATATAGAGATGTTTTAATAGGTATAACAGCAAGTGGTAGAACTCCTTATGTTATTGCGGCATTA
AACTATTCCAAAAGTATAAGTGCACTAAGTATTTCTATTTCATCTGTTCCCGAAAGTGATTCAACTTTAGATAATGATAT
TGATATTAGGCTGATTACTGGACCTGAAATTCTTGCTGGTTCCACAAGATTAAAAGCAGGAACTGCTACAAAGATGGCTT
TAAATATAATTTCTACATCTGTGATGATTAAATTAGGCAAGGTTTATGGTAATAGAATGATTGATTTATCAGTATCAAAC
GATAAATTATTGGATAGAGCAATCGGTATTTTATTTGATATTGGATCGGTTGATAAAGATACTGCTGTTCGACTTTTAAA
GAAGACAAATGGATCTGTAAAACTATCTTTATTAATTGCTTTGTCTGGAATGGATGTTATAGATGCAAAGCAATTACTTA
ATGATTCAAAGGGTAATTTAAGAACTGCACTAATTAGCTTTAAAGATAATTGA

Upstream 100 bases:

>100_bases
ATTTAGAAGTGGGAAATTGGCAAAATCAAGATAATTTAAATGGACAAATATCCTCTAATGATCAACTCCAAGATATAAAA
AAGCGTTTAGAAAATCTTTT

Downstream 100 bases:

>100_bases
ATTATGTTCAATTAAACTTTAAGTATACATATTATACTTTCTGCAATAAACTTTAAAAGTAGTTATTATTAGAAAAATTT
ATTTGAGTTATGTCTAAAGT

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSDTNNHSKNIIHRILTEQINLTSNELDTKSTKEIVNIFSEADKEPQKAVERVIPELINAIDEITARLKSKGRLFYIGAG
TSGRLGVLDASECPPTFCSNPDLVQGIIAGGIPSLTRSSEHLEDVSEIAIADLKDRNFSYRDVLIGITASGRTPYVIAAL
NYSKSISALSISISSVPESDSTLDNDIDIRLITGPEILAGSTRLKAGTATKMALNIISTSVMIKLGKVYGNRMIDLSVSN
DKLLDRAIGILFDIGSVDKDTAVRLLKKTNGSVKLSLLIALSGMDVIDAKQLLNDSKGNLRTALISFKDN

Sequences:

>Translated_310_residues
MSDTNNHSKNIIHRILTEQINLTSNELDTKSTKEIVNIFSEADKEPQKAVERVIPELINAIDEITARLKSKGRLFYIGAG
TSGRLGVLDASECPPTFCSNPDLVQGIIAGGIPSLTRSSEHLEDVSEIAIADLKDRNFSYRDVLIGITASGRTPYVIAAL
NYSKSISALSISISSVPESDSTLDNDIDIRLITGPEILAGSTRLKAGTATKMALNIISTSVMIKLGKVYGNRMIDLSVSN
DKLLDRAIGILFDIGSVDKDTAVRLLKKTNGSVKLSLLIALSGMDVIDAKQLLNDSKGNLRTALISFKDN
>Mature_309_residues
SDTNNHSKNIIHRILTEQINLTSNELDTKSTKEIVNIFSEADKEPQKAVERVIPELINAIDEITARLKSKGRLFYIGAGT
SGRLGVLDASECPPTFCSNPDLVQGIIAGGIPSLTRSSEHLEDVSEIAIADLKDRNFSYRDVLIGITASGRTPYVIAALN
YSKSISALSISISSVPESDSTLDNDIDIRLITGPEILAGSTRLKAGTATKMALNIISTSVMIKLGKVYGNRMIDLSVSND
KLLDRAIGILFDIGSVDKDTAVRLLKKTNGSVKLSLLIALSGMDVIDAKQLLNDSKGNLRTALISFKDN

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=293, Percent_Identity=42.320819112628, Blast_Score=237, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_PROM1 (A2C236)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014811.1
- ProteinModelPortal:   A2C236
- SMR:   A2C236
- STRING:   A2C236
- GeneID:   4780590
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_09881
- eggNOG:   COG2103
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- ProtClustDB:   PRK05441
- BioCyc:   PMAR167555:NATL1_09881-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 33431; Mature: 33300

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 92-92 ACT_SITE 123-123

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTNNHSKNIIHRILTEQINLTSNELDTKSTKEIVNIFSEADKEPQKAVERVIPELINA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IDEITARLKSKGRLFYIGAGTSGRLGVLDASECPPTFCSNPDLVQGIIAGGIPSLTRSSE
HHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCHH
HLEDVSEIAIADLKDRNFSYRDVLIGITASGRTPYVIAALNYSKSISALSISISSVPESD
HHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEEEEECCCCCCEEEEEEECCCCCCC
STLDNDIDIRLITGPEILAGSTRLKAGTATKMALNIISTSVMIKLGKVYGNRMIDLSVSN
CCCCCCCEEEEEECCCEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
DKLLDRAIGILFDIGSVDKDTAVRLLKKTNGSVKLSLLIALSGMDVIDAKQLLNDSKGNL
HHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCE
RTALISFKDN
EEEEEEECCC
>Mature Secondary Structure 
SDTNNHSKNIIHRILTEQINLTSNELDTKSTKEIVNIFSEADKEPQKAVERVIPELINA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IDEITARLKSKGRLFYIGAGTSGRLGVLDASECPPTFCSNPDLVQGIIAGGIPSLTRSSE
HHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCHH
HLEDVSEIAIADLKDRNFSYRDVLIGITASGRTPYVIAALNYSKSISALSISISSVPESD
HHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEEEEECCCCCCEEEEEEECCCCCCC
STLDNDIDIRLITGPEILAGSTRLKAGTATKMALNIISTSVMIKLGKVYGNRMIDLSVSN
CCCCCCCEEEEEECCCEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
DKLLDRAIGILFDIGSVDKDTAVRLLKKTNGSVKLSLLIALSGMDVIDAKQLLNDSKGNL
HHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCE
RTALISFKDN
EEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA