Click here to switch to the map view.

The map label for this gene is glpX [C]

Identifier: 124025512

GI number: 124025512

Start: 741306

End: 742310

Strand: Direct

Name: glpX [C]

Synonym: NATL1_08051

Alternate gene names: 124025512

Gene position: 741306-742310 (Clockwise)

Preceding gene: 124025510

Following gene: 124025513

Centisome position: 39.75

GC content: 41.89

Gene sequence:

>1005_bases
GTGGATCGTACTCTCGTCCAAGAAATTCTTGAAGTAGTTGAGCAAGCTGCAATTGCTTCGGCTCAATTGACTGGTTTGGG
TCAAAAAGATGAGGCTGATGCCGCCGCCGTAGAGGCAATGCGAAAGAGAATGGGAACGATTCAAATGCAAGGAAGAATCG
TTATTGGAGAAGGAGAAAGAGATGAAGCTCCAATGCTTTATATAGGAGAAGAAGTTGGATCAGGAACAGGTCCTGGAGTT
GATTTCGCTGTAGATCCTTGTGAGGGGACAAATTTATGTGCTAACAGTCAGCGTGGATCGATGGCTGTTTTAGCAGCGTC
AGATAGGGGAGGATTATTTAACGCTCCAGATTTTTATATGAATAAATTAGCTGCTCCTCCAGCAGCTAAAGGCAAAGTTG
ATATCAGAAAAACTCCCACAGAAAATATAAAAATCTTGAGTGACTGTCTTGGTATCGCAATTAGTGATTTAACTATTGTT
GTTATGGATAGAGCTAGACACAAAAATCTAGTTTCCGAAATTAGATCTACTGGTGCCAGGATTCAGCCTATTTCAGATGG
AGATGTCCAAGCGGCAATTGCATGTGGATTTGAAGGGACTGGTACTCATTGCTTAATGGGCATTGGAGCGGCTCCTGAGG
GGGTTATTTCAGCAGCGGCCATGAGGGCACTTGGAGGACATTTTCAGGGACAACTTGTTTATGATCCTGCAATAGCTCAA
ACATCAGAGTGGGCAGACTATACAAAAGAGGGAAATATAAAAAGATTGAATGAAATGGGCATAACTGATATTGACAAGAT
CTATGAAGCGAATGAACTTGCCTCAGGAGAAAATGTAGCTTTTGCTGGTAGTGGAATTACAGATGGATTGCTTTTCGATG
GAGTTAAATTTGAAAAAGACTGCACCAGAACTAGCAGTCTTGTGATTAGTACGCTTGATCAAACAGCAAGGTTTACCAAT
ACAGTTCACATCAAAGATGGTGCTCAAAGCATCTCTTTGAAGTGA

Upstream 100 bases:

>100_bases
GTTTTTTGTGAGTACTTTTTTCTGAGCATTTTTCAATGCCCTCAATTACTTACAATATTGTCTGCCTTAAGGCGTAAATT
TCTTTACCTAGCTGCAAAAA

Downstream 100 bases:

>100_bases
TAGTTAAGTAAATGAAGTAAGGGGCTATTTATGCATATTGCTGTCGTCGGTCTTAGCCATCGCACGGCCCCTGTCGAAGT
GCGTGAAAAGCTAAGTATCC

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2/SBPase

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MDRTLVQEILEVVEQAAIASAQLTGLGQKDEADAAAVEAMRKRMGTIQMQGRIVIGEGERDEAPMLYIGEEVGSGTGPGV
DFAVDPCEGTNLCANSQRGSMAVLAASDRGGLFNAPDFYMNKLAAPPAAKGKVDIRKTPTENIKILSDCLGIAISDLTIV
VMDRARHKNLVSEIRSTGARIQPISDGDVQAAIACGFEGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAIAQ
TSEWADYTKEGNIKRLNEMGITDIDKIYEANELASGENVAFAGSGITDGLLFDGVKFEKDCTRTSSLVISTLDQTARFTN
TVHIKDGAQSISLK

Sequences:

>Translated_334_residues
MDRTLVQEILEVVEQAAIASAQLTGLGQKDEADAAAVEAMRKRMGTIQMQGRIVIGEGERDEAPMLYIGEEVGSGTGPGV
DFAVDPCEGTNLCANSQRGSMAVLAASDRGGLFNAPDFYMNKLAAPPAAKGKVDIRKTPTENIKILSDCLGIAISDLTIV
VMDRARHKNLVSEIRSTGARIQPISDGDVQAAIACGFEGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAIAQ
TSEWADYTKEGNIKRLNEMGITDIDKIYEANELASGENVAFAGSGITDGLLFDGVKFEKDCTRTSSLVISTLDQTARFTN
TVHIKDGAQSISLK
>Mature_334_residues
MDRTLVQEILEVVEQAAIASAQLTGLGQKDEADAAAVEAMRKRMGTIQMQGRIVIGEGERDEAPMLYIGEEVGSGTGPGV
DFAVDPCEGTNLCANSQRGSMAVLAASDRGGLFNAPDFYMNKLAAPPAAKGKVDIRKTPTENIKILSDCLGIAISDLTIV
VMDRARHKNLVSEIRSTGARIQPISDGDVQAAIACGFEGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAIAQ
TSEWADYTKEGNIKRLNEMGITDIDKIYEANELASGENVAFAGSGITDGLLFDGVKFEKDCTRTSSLVISTLDQTARFTN
TVHIKDGAQSISLK

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family

Homologues:

Organism=Escherichia coli, GI1790360, Length=326, Percent_Identity=40.4907975460123, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1789298, Length=325, Percent_Identity=38.7692307692308, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FBSB_PROM1 (A2C1K3)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014628.1
- ProteinModelPortal:   A2C1K3
- SMR:   A2C1K3
- STRING:   A2C1K3
- GeneID:   4779894
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_08051
- eggNOG:   COG1494
- HOGENOM:   HBG284837
- OMA:   TSEWADM
- ProtClustDB:   PRK09479
- BioCyc:   PMAR167555:NATL1_08051-MONOMER
- InterPro:   IPR004464
- PIRSF:   PIRSF004532
- TIGRFAMs:   TIGR00330

Pfam domain/function: PF03320 FBPase_glpX

EC number: =3.1.3.11; =3.1.3.37

Molecular weight: Translated: 35271; Mature: 35271

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: BINDING 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRTLVQEILEVVEQAAIASAQLTGLGQKDEADAAAVEAMRKRMGTIQMQGRIVIGEGER
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCEEEECCEEEEECCCC
DEAPMLYIGEEVGSGTGPGVDFAVDPCEGTNLCANSQRGSMAVLAASDRGGLFNAPDFYM
CCCCEEEEEHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHH
NKLAAPPAAKGKVDIRKTPTENIKILSDCLGIAISDLTIVVMDRARHKNLVSEIRSTGAR
HHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHCCCE
IQPISDGDVQAAIACGFEGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAIAQ
EEECCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHC
TSEWADYTKEGNIKRLNEMGITDIDKIYEANELASGENVAFAGSGITDGLLFDGVKFEKD
CHHHHHHCCCCCCEEHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHCCCCCCCHH
CTRTSSLVISTLDQTARFTNTVHIKDGAQSISLK
HHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCC
>Mature Secondary Structure
MDRTLVQEILEVVEQAAIASAQLTGLGQKDEADAAAVEAMRKRMGTIQMQGRIVIGEGER
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCEEEECCEEEEECCCC
DEAPMLYIGEEVGSGTGPGVDFAVDPCEGTNLCANSQRGSMAVLAASDRGGLFNAPDFYM
CCCCEEEEEHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHH
NKLAAPPAAKGKVDIRKTPTENIKILSDCLGIAISDLTIVVMDRARHKNLVSEIRSTGAR
HHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHCCCE
IQPISDGDVQAAIACGFEGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAIAQ
EEECCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHC
TSEWADYTKEGNIKRLNEMGITDIDKIYEANELASGENVAFAGSGITDGLLFDGVKFEKD
CHHHHHHCCCCCCEEHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHCCCCCCCHH
CTRTSSLVISTLDQTARFTNTVHIKDGAQSISLK
HHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA