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The map label for this gene is typA [H]

Identifier: 124025505

GI number: 124025505

Start: 733452

End: 735248

Strand: Direct

Name: typA [H]

Synonym: NATL1_07981

Alternate gene names: 124025505

Gene position: 733452-735248 (Clockwise)

Preceding gene: 124025504

Following gene: 124025506

Centisome position: 39.33

GC content: 38.56

Gene sequence:

>1797_bases
ATGAGTTTTGATATACAAGCTATTAGGAATATCGCAATAATTGCTCACGTTGATCACGGTAAGACAACTTTGGTTGATGC
TCTTTTAAATCAATCTGGAACTTTTCGAGATAACGAGGAAGTCCCAACTTGTGCGTTGGATTCGAATGAATTGGAACGTG
AAAGAGGTATAACAATTCTTTCGAAAAACACAGCTGTTACTTATAACGATACTCGGATAAACATTGTTGATACACCAGGC
CACGCTGATTTTGGAGGAGAAGTCGAGAGGGTTTTGGGAATGGTAGATGGCTGTCTTCTTGTTGTTGATGCTAACGAGGG
ACCAATGCCACAAACTCGATTCGTTCTGAAAAAAGCTTTAGAGCAAGGATTAAGACCTATTGTGTTTGTGAATAAAATTG
ATCGTGCAAGGGTAGAACCAGAAACCGCGGTAGACAAGGTTTTAGATCTGTTTTTGGAGTTAGGCGCTGATGATGATCAA
TGTGATTTTCCTTATCTATTTGGGAGTGGATTAGGGGGGTTTGCCAAGACTGAAGTAAAAAGTGAAAACGATAATATGAA
ACCTTTATTTGAAGCAATTATTAGACAAGTTCCTCCTCCAGTTGGCGATGTGAATAAGCCTTTACAATTACAAGTCACGA
CCCTAGATTACTCAGATTTCTTAGGAACAATTATTATTGGAAGAGTACATAATGGTGTAATTAAAAACGGCCAAAGGACA
TGTTTGATAAAGGAAGACGGTAGTTTAAAAAAAGGAAGGATTAATAAATTATTAGGATTTAAGGGATTAAAAAGAATTGA
AATTGAAGAAGCAAATGCTGGAGATATAGTTGCCTTGGCTGGCTTTGATGAAGTTTCTATTGGTGAAACTGTAGCCTGCC
CTGATGAGCCGAAACCTTTACCTCTAATTAAGGTAGATGAGCCAACCTTGCAGATGACTTTTGTTGTCAATGATTCTCCT
TTTGCAGGGAAAGAGGGCAAGTTCGTAACCAGTCGGCAGTTGAAGGATCGTTTAAATAAAGAACTTCTAACGAATGTTGC
TTTAAGAGTTGAAGATACGGATTCTCCTGACCGTTTTTCTGTTAGTGGAAGGGGAGAGTTACATCTAGGAATTCTTATAG
AGACAATGAGAAGAGAGGGGTATGAATTTCAAGTTTCTCAACCACAAGTAATTTTCAGGACAATAGATGAAATTAAATGT
GAACCTGTTGAAACGCTTGTCCTTGACGTCCCTGAAGCTTCGATTGGTGCTTGTATTGAGAGCCTTGGGGTAAGAAAAGG
TGAAATGCAAAACATGGAAACTGGTACTGATCACCGAACTCAACTTGAGTTTGTTATTCCCTCAAGAGGCTTGATTGGAT
TTAGGGGTGAATTTATTCGTGCAACAAGAGGAGAAGGGATTATGAGTCATTCATTTTTTGAATACAGGCCATCTGTAGGA
GATTTTGAGCAAAGGAGAAATGGAGTCCTTATTTCATTTGAAGAGGGTGTCGCTACGTTCTATTCCCTAAAGAATGCAGA
AGACCGTGGACAATTTTTTATTACTCCTGGAGCCAAGGTTTATAAAGGAATGATTATTGGGGAGAATAAACGCCCACAGG
ATCTTGAATTAAATATCTGTAGGGCTAAACAACTTACCAATATGCGATCAGCTGGTGCAGAGGAGCTAGATCAATTGCAA
TCCCCAATTGAAATGACATTAGAAAGAGCTCTTGAATACATTGGACCAGGTGAGATGTTGGAAGTTACTCCTGAATCAAT
AAGGCTTAGAAAAATTAAAGCAAAGAAAAATTTGTAA

Upstream 100 bases:

>100_bases
TATTCGATATTTTGATTGGCATTTAAAACAGCTAAATGAAGTCATCGTGAGATATTCTTTATGTTTCTATTAACCAAAAG
AATTTTAATTTTTTTAAATT

Downstream 100 bases:

>100_bases
AGATAATGAACCCTATGGATAATGAAGATAATTTATTTATAAATGATGCTCGTTTTGAAATAGGAATGAAATTATTTAAT
TCTTGTCAGTGGTACAAATC

Product: tyrosine binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MSFDIQAIRNIAIIAHVDHGKTTLVDALLNQSGTFRDNEEVPTCALDSNELERERGITILSKNTAVTYNDTRINIVDTPG
HADFGGEVERVLGMVDGCLLVVDANEGPMPQTRFVLKKALEQGLRPIVFVNKIDRARVEPETAVDKVLDLFLELGADDDQ
CDFPYLFGSGLGGFAKTEVKSENDNMKPLFEAIIRQVPPPVGDVNKPLQLQVTTLDYSDFLGTIIIGRVHNGVIKNGQRT
CLIKEDGSLKKGRINKLLGFKGLKRIEIEEANAGDIVALAGFDEVSIGETVACPDEPKPLPLIKVDEPTLQMTFVVNDSP
FAGKEGKFVTSRQLKDRLNKELLTNVALRVEDTDSPDRFSVSGRGELHLGILIETMRREGYEFQVSQPQVIFRTIDEIKC
EPVETLVLDVPEASIGACIESLGVRKGEMQNMETGTDHRTQLEFVIPSRGLIGFRGEFIRATRGEGIMSHSFFEYRPSVG
DFEQRRNGVLISFEEGVATFYSLKNAEDRGQFFITPGAKVYKGMIIGENKRPQDLELNICRAKQLTNMRSAGAEELDQLQ
SPIEMTLERALEYIGPGEMLEVTPESIRLRKIKAKKNL

Sequences:

>Translated_598_residues
MSFDIQAIRNIAIIAHVDHGKTTLVDALLNQSGTFRDNEEVPTCALDSNELERERGITILSKNTAVTYNDTRINIVDTPG
HADFGGEVERVLGMVDGCLLVVDANEGPMPQTRFVLKKALEQGLRPIVFVNKIDRARVEPETAVDKVLDLFLELGADDDQ
CDFPYLFGSGLGGFAKTEVKSENDNMKPLFEAIIRQVPPPVGDVNKPLQLQVTTLDYSDFLGTIIIGRVHNGVIKNGQRT
CLIKEDGSLKKGRINKLLGFKGLKRIEIEEANAGDIVALAGFDEVSIGETVACPDEPKPLPLIKVDEPTLQMTFVVNDSP
FAGKEGKFVTSRQLKDRLNKELLTNVALRVEDTDSPDRFSVSGRGELHLGILIETMRREGYEFQVSQPQVIFRTIDEIKC
EPVETLVLDVPEASIGACIESLGVRKGEMQNMETGTDHRTQLEFVIPSRGLIGFRGEFIRATRGEGIMSHSFFEYRPSVG
DFEQRRNGVLISFEEGVATFYSLKNAEDRGQFFITPGAKVYKGMIIGENKRPQDLELNICRAKQLTNMRSAGAEELDQLQ
SPIEMTLERALEYIGPGEMLEVTPESIRLRKIKAKKNL
>Mature_597_residues
SFDIQAIRNIAIIAHVDHGKTTLVDALLNQSGTFRDNEEVPTCALDSNELERERGITILSKNTAVTYNDTRINIVDTPGH
ADFGGEVERVLGMVDGCLLVVDANEGPMPQTRFVLKKALEQGLRPIVFVNKIDRARVEPETAVDKVLDLFLELGADDDQC
DFPYLFGSGLGGFAKTEVKSENDNMKPLFEAIIRQVPPPVGDVNKPLQLQVTTLDYSDFLGTIIIGRVHNGVIKNGQRTC
LIKEDGSLKKGRINKLLGFKGLKRIEIEEANAGDIVALAGFDEVSIGETVACPDEPKPLPLIKVDEPTLQMTFVVNDSPF
AGKEGKFVTSRQLKDRLNKELLTNVALRVEDTDSPDRFSVSGRGELHLGILIETMRREGYEFQVSQPQVIFRTIDEIKCE
PVETLVLDVPEASIGACIESLGVRKGEMQNMETGTDHRTQLEFVIPSRGLIGFRGEFIRATRGEGIMSHSFFEYRPSVGD
FEQRRNGVLISFEEGVATFYSLKNAEDRGQFFITPGAKVYKGMIIGENKRPQDLELNICRAKQLTNMRSAGAEELDQLQS
PIEMTLERALEYIGPGEMLEVTPESIRLRKIKAKKNL

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=323, Percent_Identity=32.8173374613003, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI94966754, Length=157, Percent_Identity=40.7643312101911, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI34147630, Length=300, Percent_Identity=30, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI18390331, Length=147, Percent_Identity=42.1768707482993, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=39.3103448275862, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI25306283, Length=145, Percent_Identity=40, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI19923640, Length=145, Percent_Identity=40, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI25306287, Length=145, Percent_Identity=40, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI217272894, Length=140, Percent_Identity=38.5714285714286, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI217272892, Length=140, Percent_Identity=38.5714285714286, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=42.7272727272727, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=42.7272727272727, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=42.7272727272727, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI94966752, Length=153, Percent_Identity=32.6797385620915, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI5729864, Length=318, Percent_Identity=25.7861635220126, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI223555963, Length=318, Percent_Identity=26.1006289308176, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI48994988, Length=596, Percent_Identity=54.1946308724832, Blast_Score=638, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=544, Percent_Identity=27.3897058823529, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1789738, Length=140, Percent_Identity=43.5714285714286, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790412, Length=296, Percent_Identity=28.3783783783784, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789737, Length=296, Percent_Identity=28.3783783783784, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=34.4827586206897, Blast_Score=90, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17557151, Length=237, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17506493, Length=219, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17533571, Length=146, Percent_Identity=43.1506849315069, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=40.1408450704225, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988811, Length=134, Percent_Identity=38.8059701492537, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=134, Percent_Identity=38.8059701492537, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17556456, Length=276, Percent_Identity=28.6231884057971, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=138, Percent_Identity=34.7826086956522, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25141371, Length=240, Percent_Identity=27.0833333333333, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994658, Length=305, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=530, Percent_Identity=27.3584905660377, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6324707, Length=208, Percent_Identity=35.0961538461538, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320593, Length=208, Percent_Identity=35.0961538461538, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324761, Length=270, Percent_Identity=31.8518518518519, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323098, Length=149, Percent_Identity=37.5838926174497, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322359, Length=151, Percent_Identity=37.7483443708609, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=146, Percent_Identity=37.6712328767123, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI78706572, Length=521, Percent_Identity=25.7197696737044, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281363316, Length=268, Percent_Identity=31.3432835820896, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17864358, Length=268, Percent_Identity=31.3432835820896, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24582462, Length=141, Percent_Identity=44.6808510638298, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24585711, Length=164, Percent_Identity=37.1951219512195, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585713, Length=164, Percent_Identity=37.1951219512195, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585709, Length=164, Percent_Identity=37.1951219512195, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574573, Length=202, Percent_Identity=35.1485148514851, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21357743, Length=192, Percent_Identity=36.4583333333333, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221458488, Length=144, Percent_Identity=43.75, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19921738, Length=272, Percent_Identity=30.5147058823529, Blast_Score=91, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66442; Mature: 66311

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDIQAIRNIAIIAHVDHGKTTLVDALLNQSGTFRDNEEVPTCALDSNELERERGITIL
CCCCHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHCCCEEE
SKNTAVTYNDTRINIVDTPGHADFGGEVERVLGMVDGCLLVVDANEGPMPQTRFVLKKAL
ECCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQGLRPIVFVNKIDRARVEPETAVDKVLDLFLELGADDDQCDFPYLFGSGLGGFAKTEVK
HHCCCCEEEEECCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEECCCC
SENDNMKPLFEAIIRQVPPPVGDVNKPLQLQVTTLDYSDFLGTIIIGRVHNGVIKNGQRT
CCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHEEEEHHHCCHHCCCCEE
CLIKEDGSLKKGRINKLLGFKGLKRIEIEEANAGDIVALAGFDEVSIGETVACPDEPKPL
EEEECCCCCCCCHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEECCCCCCCC
PLIKVDEPTLQMTFVVNDSPFAGKEGKFVTSRQLKDRLNKELLTNVALRVEDTDSPDRFS
CEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEECCCCCCEEE
VSGRGELHLGILIETMRREGYEFQVSQPQVIFRTIDEIKCEPVETLVLDVPEASIGACIE
ECCCCCEEEHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHH
SLGVRKGEMQNMETGTDHRTQLEFVIPSRGLIGFRGEFIRATRGEGIMSHSFFEYRPSVG
HHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCC
DFEQRRNGVLISFEEGVATFYSLKNAEDRGQFFITPGAKVYKGMIIGENKRPQDLELNIC
CHHHHCCCEEEEECCCCEEHHHHCCCCCCCCEEECCCHHHHEEEEEECCCCCCCCEEEEE
RAKQLTNMRSAGAEELDQLQSPIEMTLERALEYIGPGEMLEVTPESIRLRKIKAKKNL
HHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEHHCCCC
>Mature Secondary Structure 
SFDIQAIRNIAIIAHVDHGKTTLVDALLNQSGTFRDNEEVPTCALDSNELERERGITIL
CCCHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHCCCEEE
SKNTAVTYNDTRINIVDTPGHADFGGEVERVLGMVDGCLLVVDANEGPMPQTRFVLKKAL
ECCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQGLRPIVFVNKIDRARVEPETAVDKVLDLFLELGADDDQCDFPYLFGSGLGGFAKTEVK
HHCCCCEEEEECCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEECCCC
SENDNMKPLFEAIIRQVPPPVGDVNKPLQLQVTTLDYSDFLGTIIIGRVHNGVIKNGQRT
CCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHEEEEHHHCCHHCCCCEE
CLIKEDGSLKKGRINKLLGFKGLKRIEIEEANAGDIVALAGFDEVSIGETVACPDEPKPL
EEEECCCCCCCCHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEECCCCCCCC
PLIKVDEPTLQMTFVVNDSPFAGKEGKFVTSRQLKDRLNKELLTNVALRVEDTDSPDRFS
CEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEECCCCCCEEE
VSGRGELHLGILIETMRREGYEFQVSQPQVIFRTIDEIKCEPVETLVLDVPEASIGACIE
ECCCCCEEEHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHH
SLGVRKGEMQNMETGTDHRTQLEFVIPSRGLIGFRGEFIRATRGEGIMSHSFFEYRPSVG
HHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCC
DFEQRRNGVLISFEEGVATFYSLKNAEDRGQFFITPGAKVYKGMIIGENKRPQDLELNIC
CHHHHCCCEEEEECCCCEEHHHHCCCCCCCCEEECCCHHHHEEEEEECCCCCCCCEEEEE
RAKQLTNMRSAGAEELDQLQSPIEMTLERALEYIGPGEMLEVTPESIRLRKIKAKKNL
HHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]