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The map label for this gene is vanY [H]

Identifier: 124025504

GI number: 124025504

Start: 732687

End: 733319

Strand: Direct

Name: vanY [H]

Synonym: NATL1_07971

Alternate gene names: 124025504

Gene position: 732687-733319 (Clockwise)

Preceding gene: 124025502

Following gene: 124025505

Centisome position: 39.29

GC content: 34.44

Gene sequence:

>633_bases
ATGGGACTTCTATTCCTTGGCCTTAGTATATCGCTTACGTTTTTAGTTAATAAATCATTTTTAAGTCAAAGAAAATCCTT
AGATGATTCGAGTAACTCCATTGAGACAAGGCAAAATAAAAGCTTGTTAGGTCATCTTCCTTATAAAGAGGCTTCCAAAA
AAGATTTAATTCTTTTTTCTCCAGGTATTTACGTTCATAAAGATATCTATGAAAAATTTAAGGAAATGCAATTTATGGCT
GCACAAAGAGGGGTTTCTCTTCAACTATTAAGTGGTTATAGATCAATAAATTTGCAAAGGGATATTTTTTATGAAAATAA
ATCTATTAGAAATCAAACTGCTGTTGAGCGCTCAAGAGACTCAGCTCCTCCTGGTTATTCTGAACACAGCACAGGGTATG
CAATCGATGTTGGCGATGGAAATTATCCAGATACTCATTTTGAGGTTGAATTTGAACAAACGCCTGCTTTTAAATGGATG
AAGAGGTTTGCCTCTAAATATCATTTCGTTCTTTCTTTTCCACCCAACAACAAACAGGGAGTAACTTATGAGCCTTGGCA
TTGGAGATTTGAGGGGACTGTTAAAGCTTTGAGGGAATTTGACGCTGCCAATAAAATTATAAAATTCAAATAA

Upstream 100 bases:

>100_bases
GTTTTGACCATAAGCAGATCGTATGAATTATCAAGATGACATCCCGCTGGCAAGAAGGATTAAATCCATCAAAACCTTTA
CTACCAGGTCTTTTTTGCCT

Downstream 100 bases:

>100_bases
ATATGACTTAATTTTTTTTACTTCGAATTTTATATTCGATATTTTGATTGGCATTTAAAACAGCTAAATGAAGTCATCGT
GAGATATTCTTTATGTTTCT

Product: putative carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MGLLFLGLSISLTFLVNKSFLSQRKSLDDSSNSIETRQNKSLLGHLPYKEASKKDLILFSPGIYVHKDIYEKFKEMQFMA
AQRGVSLQLLSGYRSINLQRDIFYENKSIRNQTAVERSRDSAPPGYSEHSTGYAIDVGDGNYPDTHFEVEFEQTPAFKWM
KRFASKYHFVLSFPPNNKQGVTYEPWHWRFEGTVKALREFDAANKIIKFK

Sequences:

>Translated_210_residues
MGLLFLGLSISLTFLVNKSFLSQRKSLDDSSNSIETRQNKSLLGHLPYKEASKKDLILFSPGIYVHKDIYEKFKEMQFMA
AQRGVSLQLLSGYRSINLQRDIFYENKSIRNQTAVERSRDSAPPGYSEHSTGYAIDVGDGNYPDTHFEVEFEQTPAFKWM
KRFASKYHFVLSFPPNNKQGVTYEPWHWRFEGTVKALREFDAANKIIKFK
>Mature_209_residues
GLLFLGLSISLTFLVNKSFLSQRKSLDDSSNSIETRQNKSLLGHLPYKEASKKDLILFSPGIYVHKDIYEKFKEMQFMAA
QRGVSLQLLSGYRSINLQRDIFYENKSIRNQTAVERSRDSAPPGYSEHSTGYAIDVGDGNYPDTHFEVEFEQTPAFKWMK
RFASKYHFVLSFPPNNKQGVTYEPWHWRFEGTVKALREFDAANKIIKFK

Specific function: Vancomycin-inducible, penicillin-resistant, DD- carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D- alanine-containing peptidoglycan precursors. Insensitive to beta- lactams [H]

COG id: COG1876

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003709 [H]

Pfam domain/function: PF02557 VanY [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 24325; Mature: 24194

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLFLGLSISLTFLVNKSFLSQRKSLDDSSNSIETRQNKSLLGHLPYKEASKKDLILFS
CCEEEEEHHEEEEEEECHHHHHHHHCCCCCCCCCHHHCCCCCEECCCCCCCCCCCEEEEC
PGIYVHKDIYEKFKEMQFMAAQRGVSLQLLSGYRSINLQRDIFYENKSIRNQTAVERSRD
CCCEEEHHHHHHHHHHHHHHHHCCCEEEEECCCHHCCCCHHEEECCCCCCHHHHHHHCCC
SAPPGYSEHSTGYAIDVGDGNYPDTHFEVEFEQTPAFKWMKRFASKYHFVLSFPPNNKQG
CCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCEEEEEEECCCCCCC
VTYEPWHWRFEGTVKALREFDAANKIIKFK
CEECCCEEEEHHHHHHHHHHHHHCCEEECC
>Mature Secondary Structure 
GLLFLGLSISLTFLVNKSFLSQRKSLDDSSNSIETRQNKSLLGHLPYKEASKKDLILFS
CEEEEEHHEEEEEEECHHHHHHHHCCCCCCCCCHHHCCCCCEECCCCCCCCCCCEEEEC
PGIYVHKDIYEKFKEMQFMAAQRGVSLQLLSGYRSINLQRDIFYENKSIRNQTAVERSRD
CCCEEEHHHHHHHHHHHHHHHHCCCEEEEECCCHHCCCCHHEEECCCCCCHHHHHHHCCC
SAPPGYSEHSTGYAIDVGDGNYPDTHFEVEFEQTPAFKWMKRFASKYHFVLSFPPNNKQG
CCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCEEEEEEECCCCCCC
VTYEPWHWRFEGTVKALREFDAANKIIKFK
CEECCCEEEEHHHHHHHHHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1398115; 8380148 [H]