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The map label for this gene is hslO

Identifier: 124025429

GI number: 124025429

Start: 666311

End: 667210

Strand: Reverse

Name: hslO

Synonym: NATL1_07221

Alternate gene names: 124025429

Gene position: 667210-666311 (Counterclockwise)

Preceding gene: 124025430

Following gene: 124025425

Centisome position: 35.78

GC content: 36.89

Gene sequence:

>900_bases
ATGACAGATTCACTAGTTAGAGCGACTGCTGCAAAAGGGGGGATCAGACTAGTCGCCGTATCAACGACTGAATCTACAAA
AGAAGCAAAAGAAAGACATTCTCTTTCCTATTTAACTTCTGCAATTGTAGGTAGGGCAATGAGTGCAAGCCTTTTGCTAG
CAAGCTCAATGAAGGTAAATCATGGAAGGGTGACTTTGAGGATAAGCTCAAATGGACCACTAAAAGGATTAACTATTGAT
GCGGGTAGAGATGGAAGTGTGAGAGGCTACGTTGGCGATCCAAGTCTTGAATTAGACCTAATTAAGAATAAAAGCAACCA
CTATACATTTGATTTCAAAAAAGCTACAGGTATTGGCTATCTTCACGTTATTAGAGATGACGGAAAAGGTGAACCACACA
ACAGCACAGTCGAATTAATTAATGGAGGGATAGGTGAAGACATAGCTTCCTATTTATTACATTCCGAACAAACGCCCTCT
GCTGTGTTTGTTGGAGAAAGAATCAATCAAGATGGGATAGTTTGTAGCGGAGGACTTTTAGCACAAATACTACCTAAAGC
AGAACGAGATTATTCATTGATAGACTTACTTGAAGATCGATGTAAAGAGATTAACTCTTTTAGTGAGTTATTAAACAAAA
AAGGGAATAACCTTATTTCTCTTATTGAAGAGATTTTCCCAGATCTTGATCAATCACCTTCAGATATTATTAGCACATCT
CAGGAAGTTCGTTTTAAATGTAGATGTTCAAGAGAAAGAAGCCTATCAGCGTTAAAGATTTTGGGGAAAGATGAACTTCA
GAAAATGATAAAGGAAGATGGGAAAGCAGAACTAACATGTCAATTCTGTAAAAATGTTTATCTTGTTAAAGAGGACGAAT
TGATATCTTTAATCGATTAA

Upstream 100 bases:

>100_bases
ATAGTTACCCATGAACCCGAACTTTTTAAAAATTTGAATACCGACAATTACAAGTTGCACAATGGTCAACTTATCCCTCA
ATAAACAATTCAACTAATCA

Downstream 100 bases:

>100_bases
AGGATTAATCAAGGAAAACCACTCCTAACCAAAGCAAAAATACTGCAGGTATCGCCTCAAATTTGTCTGAAGATAATGAT
CCAGCGTTATCAATAAATGA

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTDSLVRATAAKGGIRLVAVSTTESTKEAKERHSLSYLTSAIVGRAMSASLLLASSMKVNHGRVTLRISSNGPLKGLTID
AGRDGSVRGYVGDPSLELDLIKNKSNHYTFDFKKATGIGYLHVIRDDGKGEPHNSTVELINGGIGEDIASYLLHSEQTPS
AVFVGERINQDGIVCSGGLLAQILPKAERDYSLIDLLEDRCKEINSFSELLNKKGNNLISLIEEIFPDLDQSPSDIISTS
QEVRFKCRCSRERSLSALKILGKDELQKMIKEDGKAELTCQFCKNVYLVKEDELISLID

Sequences:

>Translated_299_residues
MTDSLVRATAAKGGIRLVAVSTTESTKEAKERHSLSYLTSAIVGRAMSASLLLASSMKVNHGRVTLRISSNGPLKGLTID
AGRDGSVRGYVGDPSLELDLIKNKSNHYTFDFKKATGIGYLHVIRDDGKGEPHNSTVELINGGIGEDIASYLLHSEQTPS
AVFVGERINQDGIVCSGGLLAQILPKAERDYSLIDLLEDRCKEINSFSELLNKKGNNLISLIEEIFPDLDQSPSDIISTS
QEVRFKCRCSRERSLSALKILGKDELQKMIKEDGKAELTCQFCKNVYLVKEDELISLID
>Mature_298_residues
TDSLVRATAAKGGIRLVAVSTTESTKEAKERHSLSYLTSAIVGRAMSASLLLASSMKVNHGRVTLRISSNGPLKGLTIDA
GRDGSVRGYVGDPSLELDLIKNKSNHYTFDFKKATGIGYLHVIRDDGKGEPHNSTVELINGGIGEDIASYLLHSEQTPSA
VFVGERINQDGIVCSGGLLAQILPKAERDYSLIDLLEDRCKEINSFSELLNKKGNNLISLIEEIFPDLDQSPSDIISTSQ
EVRFKCRCSRERSLSALKILGKDELQKMIKEDGKAELTCQFCKNVYLVKEDELISLID

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=286, Percent_Identity=25.8741258741259, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_PROM1 (A2C1C0)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014545.1
- ProteinModelPortal:   A2C1C0
- SMR:   A2C1C0
- STRING:   A2C1C0
- GeneID:   4780038
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_07221
- eggNOG:   COG1281
- HOGENOM:   HBG286231
- OMA:   VMLGRAM
- ProtClustDB:   PRK00114
- BioCyc:   PMAR167555:NATL1_07221-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32720; Mature: 32588

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSLVRATAAKGGIRLVAVSTTESTKEAKERHSLSYLTSAIVGRAMSASLLLASSMKVN
CCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEC
HGRVTLRISSNGPLKGLTIDAGRDGSVRGYVGDPSLELDLIKNKSNHYTFDFKKATGIGY
CCEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEECCCCCEEEEEECCCCCEE
LHVIRDDGKGEPHNSTVELINGGIGEDIASYLLHSEQTPSAVFVGERINQDGIVCSGGLL
EEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCHH
AQILPKAERDYSLIDLLEDRCKEINSFSELLNKKGNNLISLIEEIFPDLDQSPSDIISTS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHCCC
QEVRFKCRCSRERSLSALKILGKDELQKMIKEDGKAELTCQFCKNVYLVKEDELISLID
HHHEEEEECCCCCCHHHHHHCCHHHHHHHHHCCCCCEEEEHHHCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TDSLVRATAAKGGIRLVAVSTTESTKEAKERHSLSYLTSAIVGRAMSASLLLASSMKVN
CCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEC
HGRVTLRISSNGPLKGLTIDAGRDGSVRGYVGDPSLELDLIKNKSNHYTFDFKKATGIGY
CCEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEECCCCCEEEEEECCCCCEE
LHVIRDDGKGEPHNSTVELINGGIGEDIASYLLHSEQTPSAVFVGERINQDGIVCSGGLL
EEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCHH
AQILPKAERDYSLIDLLEDRCKEINSFSELLNKKGNNLISLIEEIFPDLDQSPSDIISTS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHCCC
QEVRFKCRCSRERSLSALKILGKDELQKMIKEDGKAELTCQFCKNVYLVKEDELISLID
HHHEEEEECCCCCCHHHHHHCCHHHHHHHHHCCCCCEEEEHHHCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA