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The map label for this gene is lepB1 [H]

Identifier: 124025373

GI number: 124025373

Start: 607573

End: 608139

Strand: Reverse

Name: lepB1 [H]

Synonym: NATL1_06621

Alternate gene names: 124025373

Gene position: 608139-607573 (Counterclockwise)

Preceding gene: 124025378

Following gene: 124025372

Centisome position: 32.61

GC content: 34.57

Gene sequence:

>567_bases
ATGACATCTACTGGATCAAAAAAGAATCAAAACCAAAATAGCTGGAAAGGATTGTTGGTTTGGATATTAATTGCGCTTTT
ATTAAGATGGCAAGCAGTTGAGCCTAGATGGATTCCATCTGGATCAATGATTCCAACTTTGCAAATTCAAGACAGAATAT
TGATAGAAAAAATAACCCCAAGACTTAATAATAAACTAAATAAACATTTAAATTTAAATACGATTGTTATTTTCAAACCT
CCAAAAATTCTTACAGAAGCAGGTTACAGTGATGGTTCAGCGCTAATTAAAAGAGTCGTTGGCTTACCTGGAGACAAAAT
AGAAGTAACTGATGGGAAACTATATAGAAATGGAAAAGAAATAAATGAACCTTGGATTAAAGAGCCTATCCAATATGAAA
TGGATGCAATAAATGTACCTGAATATTCACTTTGGGTCTTAGGAGACAACCGAAATAACAGTTTAGACTCTCATGTTTGG
GGAGCTCTCCCAGAAAAAAATCTTATAGGTACGGCGCTTGCAAGGTACTGGCCATTAAAAAAAATAGGGCCTATTCGGTT
CCCATAA

Upstream 100 bases:

>100_bases
TGATAAAAAAATTGTAACGAGCTAGTGAAATTGTCAAAAGAACAACTACTTGGATTTTTGTGAAAAACTTTCCAACAAGT
AACTAAAACAAAAAAAATTC

Downstream 100 bases:

>100_bases
CCTAAATTAATTTTTTTTAGTGTACATTTTGCGATAATGTAATTGTACATAGAAAAAAACTGGATGTTTAATCCTGAATT
TTTAGCTACAGACAATAATG

Product: leader peptidase I

Products: NA

Alternate protein names: SPase I-1; Leader peptidase I-1 [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MTSTGSKKNQNQNSWKGLLVWILIALLLRWQAVEPRWIPSGSMIPTLQIQDRILIEKITPRLNNKLNKHLNLNTIVIFKP
PKILTEAGYSDGSALIKRVVGLPGDKIEVTDGKLYRNGKEINEPWIKEPIQYEMDAINVPEYSLWVLGDNRNNSLDSHVW
GALPEKNLIGTALARYWPLKKIGPIRFP

Sequences:

>Translated_188_residues
MTSTGSKKNQNQNSWKGLLVWILIALLLRWQAVEPRWIPSGSMIPTLQIQDRILIEKITPRLNNKLNKHLNLNTIVIFKP
PKILTEAGYSDGSALIKRVVGLPGDKIEVTDGKLYRNGKEINEPWIKEPIQYEMDAINVPEYSLWVLGDNRNNSLDSHVW
GALPEKNLIGTALARYWPLKKIGPIRFP
>Mature_187_residues
TSTGSKKNQNQNSWKGLLVWILIALLLRWQAVEPRWIPSGSMIPTLQIQDRILIEKITPRLNNKLNKHLNLNTIVIFKPP
KILTEAGYSDGSALIKRVVGLPGDKIEVTDGKLYRNGKEINEPWIKEPIQYEMDAINVPEYSLWVLGDNRNNSLDSHVWG
ALPEKNLIGTALARYWPLKKIGPIRFP

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21427; Mature: 21296

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTGSKKNQNQNSWKGLLVWILIALLLRWQAVEPRWIPSGSMIPTLQIQDRILIEKITP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEECCCHHHHHHHCH
RLNNKLNKHLNLNTIVIFKPPKILTEAGYSDGSALIKRVVGLPGDKIEVTDGKLYRNGKE
HHHHHHHCCCCCCEEEEECCCHHHHHCCCCCHHHHHHHHHCCCCCEEEECCCCEECCCCC
INEPWIKEPIQYEMDAINVPEYSLWVLGDNRNNSLDSHVWGALPEKNLIGTALARYWPLK
CCCCHHCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHCCHH
KIGPIRFP
HCCCCCCC
>Mature Secondary Structure 
TSTGSKKNQNQNSWKGLLVWILIALLLRWQAVEPRWIPSGSMIPTLQIQDRILIEKITP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEECCCHHHHHHHCH
RLNNKLNKHLNLNTIVIFKPPKILTEAGYSDGSALIKRVVGLPGDKIEVTDGKLYRNGKE
HHHHHHHCCCCCCEEEEECCCHHHHHCCCCCHHHHHHHHHCCCCCEEEECCCCEECCCCC
INEPWIKEPIQYEMDAINVPEYSLWVLGDNRNNSLDSHVWGALPEKNLIGTALARYWPLK
CCCCHHCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHCCHH
KIGPIRFP
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]