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The map label for this gene is ppa [H]

Identifier: 124025280

GI number: 124025280

Start: 515026

End: 515553

Strand: Direct

Name: ppa [H]

Synonym: NATL1_05691

Alternate gene names: 124025280

Gene position: 515026-515553 (Clockwise)

Preceding gene: 124025279

Following gene: 124025281

Centisome position: 27.62

GC content: 39.96

Gene sequence:

>528_bases
ATGGACCTGAGTGATCTTCCTCCTTCACCATCGCCTGGATTAGTAAATCTAGTTGTAGAGATTCCTGCTGGCAGTAGAAA
TAAATACGAATATTTTAGCTCTGCAGGAATTATGGCTCTGGATAGAGTTTTGCATTCTTCAGTGAAATACCCATTTGATT
ATGGATTTGTTCCAAATACTCTTGCTGAGGATGGAGCGCCGCTTGATGCAATGGTCGTGATGGAAGAACCTACTTTTGCA
GGTTGCTTGATTCAGGCAAGACCTATAGGAGTTCTTGATATGCATGATTCTGGGGCCTACGATGGCAAACTTTTATGTGT
ACCTACTGCAGATCCAAGACAAAGAGAAATTAATACTATTAAGCAAATAGCTCAGGACCAATTGGAGGATGTGGCTGAGT
TTTTTAGAACCTATAAAAGCTTGGAAGGGAGGGTGATCGAAATAGATGGATGGAGAGACTACGATGCTGTTGATGAATTA
TTAAAAAGCTGCATAGAAGCACATCATTTGGAAATAACACAAAAATAA

Upstream 100 bases:

>100_bases
GGTTTGGCAATAGTATTTGTAATGCTAGGAATACCATTATTAGCTGTCATAAGTGAAAGGCCAGAGACAACAAAAAGCTT
AACGACTTCAATAAATCAAA

Downstream 100 bases:

>100_bases
CTATTTTAATTTTCTTTTTTGGGTAAACTTATCTTTTTAGGCTTTGAAAACTTGAAATTATTTAATTATTCCTCGTGCTC
AACTTGTCGCAGAGCGATTA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MDLSDLPPSPSPGLVNLVVEIPAGSRNKYEYFSSAGIMALDRVLHSSVKYPFDYGFVPNTLAEDGAPLDAMVVMEEPTFA
GCLIQARPIGVLDMHDSGAYDGKLLCVPTADPRQREINTIKQIAQDQLEDVAEFFRTYKSLEGRVIEIDGWRDYDAVDEL
LKSCIEAHHLEITQK

Sequences:

>Translated_175_residues
MDLSDLPPSPSPGLVNLVVEIPAGSRNKYEYFSSAGIMALDRVLHSSVKYPFDYGFVPNTLAEDGAPLDAMVVMEEPTFA
GCLIQARPIGVLDMHDSGAYDGKLLCVPTADPRQREINTIKQIAQDQLEDVAEFFRTYKSLEGRVIEIDGWRDYDAVDEL
LKSCIEAHHLEITQK
>Mature_175_residues
MDLSDLPPSPSPGLVNLVVEIPAGSRNKYEYFSSAGIMALDRVLHSSVKYPFDYGFVPNTLAEDGAPLDAMVVMEEPTFA
GCLIQARPIGVLDMHDSGAYDGKLLCVPTADPRQREINTIKQIAQDQLEDVAEFFRTYKSLEGRVIEIDGWRDYDAVDEL
LKSCIEAHHLEITQK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=174, Percent_Identity=31.6091954022989, Blast_Score=94, Evalue=5e-21,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19445; Mature: 19445

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSDLPPSPSPGLVNLVVEIPAGSRNKYEYFSSAGIMALDRVLHSSVKYPFDYGFVPNT
CCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCC
LAEDGAPLDAMVVMEEPTFAGCLIQARPIGVLDMHDSGAYDGKLLCVPTADPRQREINTI
HHCCCCCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHH
KQIAQDQLEDVAEFFRTYKSLEGRVIEIDGWRDYDAVDELLKSCIEAHHLEITQK
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCEEECC
>Mature Secondary Structure
MDLSDLPPSPSPGLVNLVVEIPAGSRNKYEYFSSAGIMALDRVLHSSVKYPFDYGFVPNT
CCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCC
LAEDGAPLDAMVVMEEPTFAGCLIQARPIGVLDMHDSGAYDGKLLCVPTADPRQREINTI
HHCCCCCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHH
KQIAQDQLEDVAEFFRTYKSLEGRVIEIDGWRDYDAVDELLKSCIEAHHLEITQK
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]