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The map label for this gene is ppa [H]

Identifier: 124025262

GI number: 124025262

Start: 499238

End: 499825

Strand: Direct

Name: ppa [H]

Synonym: NATL1_05511

Alternate gene names: 124025262

Gene position: 499238-499825 (Clockwise)

Preceding gene: 124025261

Following gene: 124025265

Centisome position: 26.77

GC content: 37.24

Gene sequence:

>588_bases
ATGGCTAACCTTGACCAAGCGCCTAGCAGAACAATGCCTAATCTGCTTCATATATTGCCTGCGTTTGCCAATGAATCTGA
ACTTAGAGTTAATACAATCGTTGAGTTAAATTCAAATACTATAAATAAATACGAACTTATTACTGAAACAGGGCATCTAA
AACTTGATCGTGTCGGATATTCTTCTCTGGCCTATCCTTTTGCTTATGGGTGTCTTCCACGGACATGGGATGAAGACGGG
GACCCACTAGATATCGAAATTGTGAATGTTACAGAGCCTTTGGTTCCCGGTTCAATTGTTGAGGCAAGGATTATAGGAAT
AATGACTTTTGATGATGGAGGTGAAGTTGACGACAAAGTTATTGGCGTAATAGCCGATGACAAGAGGATGGATCACATAC
AAAGCTTTGAACAATTAGGTAAGCATTGGATTAATGAAACAACTTATTATTGGGAGCATTACAAGGATCTTAAAAAACCA
GGAACTTGTACTGTAAATGGTTTCTTTGGTGTTGAAAAAGCAGTTCAGATTATTAAATCCTGTGAGGAGCGTTACTTATC
TGAAATAGATCCTAATTTAATTAATTAA

Upstream 100 bases:

>100_bases
AGAGGAGCATGTCTTTTGTTGAAACTTTTCTAAATTATCCGACGCAAGTCCATTTGCATTTACTGCGTTGATTTACCATG
TAAGAACATAGAAAAATACC

Downstream 100 bases:

>100_bases
ATTTTATGAATGATTTAGGCCCTTGCAGACTTGAATATCTCTTCTAATATTTCCCCTGCTCCACGGCCTTTTAATTCATT
GGCTAAGTCTATTCCTATTT

Product: putative inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MANLDQAPSRTMPNLLHILPAFANESELRVNTIVELNSNTINKYELITETGHLKLDRVGYSSLAYPFAYGCLPRTWDEDG
DPLDIEIVNVTEPLVPGSIVEARIIGIMTFDDGGEVDDKVIGVIADDKRMDHIQSFEQLGKHWINETTYYWEHYKDLKKP
GTCTVNGFFGVEKAVQIIKSCEERYLSEIDPNLIN

Sequences:

>Translated_195_residues
MANLDQAPSRTMPNLLHILPAFANESELRVNTIVELNSNTINKYELITETGHLKLDRVGYSSLAYPFAYGCLPRTWDEDG
DPLDIEIVNVTEPLVPGSIVEARIIGIMTFDDGGEVDDKVIGVIADDKRMDHIQSFEQLGKHWINETTYYWEHYKDLKKP
GTCTVNGFFGVEKAVQIIKSCEERYLSEIDPNLIN
>Mature_194_residues
ANLDQAPSRTMPNLLHILPAFANESELRVNTIVELNSNTINKYELITETGHLKLDRVGYSSLAYPFAYGCLPRTWDEDGD
PLDIEIVNVTEPLVPGSIVEARIIGIMTFDDGGEVDDKVIGVIADDKRMDHIQSFEQLGKHWINETTYYWEHYKDLKKPG
TCTVNGFFGVEKAVQIIKSCEERYLSEIDPNLIN

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=158, Percent_Identity=32.2784810126582, Blast_Score=82, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323923, Length=215, Percent_Identity=26.9767441860465, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 22062; Mature: 21931

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLDQAPSRTMPNLLHILPAFANESELRVNTIVELNSNTINKYELITETGHLKLDRVGY
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEEEECCCCEEEECCCC
SSLAYPFAYGCLPRTWDEDGDPLDIEIVNVTEPLVPGSIVEARIIGIMTFDDGGEVDDKV
HHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCEE
IGVIADDKRMDHIQSFEQLGKHWINETTYYWEHYKDLKKPGTCTVNGFFGVEKAVQIIKS
EEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHH
CEERYLSEIDPNLIN
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANLDQAPSRTMPNLLHILPAFANESELRVNTIVELNSNTINKYELITETGHLKLDRVGY
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEEEECCCCEEEECCCC
SSLAYPFAYGCLPRTWDEDGDPLDIEIVNVTEPLVPGSIVEARIIGIMTFDDGGEVDDKV
HHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCEE
IGVIADDKRMDHIQSFEQLGKHWINETTYYWEHYKDLKKPGTCTVNGFFGVEKAVQIIKS
EEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHH
CEERYLSEIDPNLIN
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1963432 [H]