Click here to switch to the map view.

The map label for this gene is ppiA [C]

Identifier: 123968865

GI number: 123968865

Start: 1107233

End: 1107838

Strand: Reverse

Name: ppiA [C]

Synonym: A9601_13321

Alternate gene names: 123968865

Gene position: 1107838-1107233 (Counterclockwise)

Preceding gene: 123968866

Following gene: 123968862

Centisome position: 66.34

GC content: 27.56

Gene sequence:

>606_bases
TTGGTTCAAGCATGTAGTTATAAAAGTAAGATTGATCCAAATTATTACTGCCAAAAACTTAAATTTAGTTGTATTCAGAG
CAATAAAGTAGTTAGTTTTAAAACTTCAAAAGGTGATTTTGCGGTAAAATTATTTGGTAAAGATAACCCAGTAACAGTAT
CAAATTTTCTGGAAAACATAGAAAATAATATTTATGTAAATCAAAAATTTTATAAAATAATAAACTACCCCCAAATAAGA
TTTATACATGGCGGCGTTAATCCGGAAAATAAATTTTATACAGAACGACAACAAAACCTGAATAAGAAAAGTCCAACAAT
ACCTTTAGAAATAAAATTCAAAGAAGAAGTAAAACCGAGATACAACTATCAAATAAAAAATCCTATTGAAACAGTAAATT
TAGTTAATACTTTTGAGAGTGGATCAATCGCTATGGTTAAAAGTGGAAAGGATAAGTCTTCATCTACTGAATTTTTTTTT
GTAACGACTAAGATCCCAGAACTAGATGGAAGATATTCGATTTTTGGAAAGATTATTAAAGGATTAGACGTACTCGAAAA
AATAAATAAAGAAGACTACATTAAGGCAGTCCAGATTTCTAATTAA

Upstream 100 bases:

>100_bases
AAGGAGCTCGTCTAGCTAAATTTTTAGATGTTAATTTGGAGGGCCTAAAATAAAAAAAAAATATTTTTTAAAAACATTAT
CTCTTATACAGGTTTTGTTT

Downstream 100 bases:

>100_bases
ATTTCTAGAGAATATTTATTTATTTTCAACATTTCTGTATTAACTCCTGAAGAGCGTTTAAGAGCTACCTTACCAGTCCT
CGCTATTTCAAGGATGCCGT

Product: cyclophilin-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase sll0227; Rotamase sll0227 [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MVQACSYKSKIDPNYYCQKLKFSCIQSNKVVSFKTSKGDFAVKLFGKDNPVTVSNFLENIENNIYVNQKFYKIINYPQIR
FIHGGVNPENKFYTERQQNLNKKSPTIPLEIKFKEEVKPRYNYQIKNPIETVNLVNTFESGSIAMVKSGKDKSSSTEFFF
VTTKIPELDGRYSIFGKIIKGLDVLEKINKEDYIKAVQISN

Sequences:

>Translated_201_residues
MVQACSYKSKIDPNYYCQKLKFSCIQSNKVVSFKTSKGDFAVKLFGKDNPVTVSNFLENIENNIYVNQKFYKIINYPQIR
FIHGGVNPENKFYTERQQNLNKKSPTIPLEIKFKEEVKPRYNYQIKNPIETVNLVNTFESGSIAMVKSGKDKSSSTEFFF
VTTKIPELDGRYSIFGKIIKGLDVLEKINKEDYIKAVQISN
>Mature_201_residues
MVQACSYKSKIDPNYYCQKLKFSCIQSNKVVSFKTSKGDFAVKLFGKDNPVTVSNFLENIENNIYVNQKFYKIINYPQIR
FIHGGVNPENKFYTERQQNLNKKSPTIPLEIKFKEEVKPRYNYQIKNPIETVNLVNTFESGSIAMVKSGKDKSSSTEFFF
VTTKIPELDGRYSIFGKIIKGLDVLEKINKEDYIKAVQISN

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 23217; Mature: 23217

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQACSYKSKIDPNYYCQKLKFSCIQSNKVVSFKTSKGDFAVKLFGKDNPVTVSNFLENI
CCCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEEECCCCEEEEEECCCCCEEHHHHHHHH
ENNIYVNQKFYKIINYPQIRFIHGGVNPENKFYTERQQNLNKKSPTIPLEIKFKEEVKPR
CCCEEECHHHEEHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCC
YNYQIKNPIETVNLVNTFESGSIAMVKSGKDKSSSTEFFFVTTKIPELDGRYSIFGKIIK
CCEEECCCHHEEEEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH
GLDVLEKINKEDYIKAVQISN
HHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure
MVQACSYKSKIDPNYYCQKLKFSCIQSNKVVSFKTSKGDFAVKLFGKDNPVTVSNFLENI
CCCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEEECCCCEEEEEECCCCCEEHHHHHHHH
ENNIYVNQKFYKIINYPQIRFIHGGVNPENKFYTERQQNLNKKSPTIPLEIKFKEEVKPR
CCCEEECHHHEEHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCC
YNYQIKNPIETVNLVNTFESGSIAMVKSGKDKSSSTEFFFVTTKIPELDGRYSIFGKIIK
CCEEECCCHHEEEEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH
GLDVLEKINKEDYIKAVQISN
HHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]