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The map label for this gene is sasA [H]

Identifier: 123968716

GI number: 123968716

Start: 997892

End: 999010

Strand: Reverse

Name: sasA [H]

Synonym: A9601_11831

Alternate gene names: 123968716

Gene position: 999010-997892 (Counterclockwise)

Preceding gene: 123968719

Following gene: 123968714

Centisome position: 59.83

GC content: 34.58

Gene sequence:

>1119_bases
TTGAATGATAAAAAAGAGCTAAAATTAATACTTGTGGCAGCTAGAAATCAACTTTCTAGTAATGATATTAAGTGCTTAAT
AGCTTATTTAGAATCAGATGATTGTGAATTTGAGACATCTCTTCAGATCTCAGAACCCAAAGAGCAACCAGAATTACTTG
AATTACATAGATTAGTCGCTATCCCTGCTCTTATAAAGGTTTCCCCAGCTCCAAAGCAAATATTTGCTGGAAGTAATATT
TTCTCTCAGTTGCAAAAATGGTTGCCAAGGTGGTCACAGGAAGGCTTAACAAAAAATCTTGGGATTAATTTGCAGCCATC
CAAAATTGATTCAACAAGAACTCAAAAAGAATTTCTATTGGAAGACGAACTTCTTGTTTTAAGACAAGAAAATGAGACAT
TAACAAAAAGAATAGAATCTCAGGAAAGATTATTAAGAATGGTCGCGCATGAATTAAGAACACCTTTAACTGCTGCTACT
TTGGCTGTTCAAAGTCAAAAACTCGGACAAATAGATATTTCAAAATTGCAGGAGGTTATTAAAAGACGTCTTGAAGAGAT
TGAACTCTTATCTCAGGATCTTTTAGAGGTTGGAACAACCAAATGGGAAGCATTATTTAATCCTCAGAAAATTGATTTAG
GTAATATTAGTGCTGAAGTAATACTCGAATTAGAAAAATTCTGGAGAATAAGGAATATTGAAATTGATACTGATATTCCA
TCTGATCTGCCAAGTGTATTTGCAGATCAAAGAAGAATGAGGCAAGTATTTTTAAATTTAATTGAAAATGCTATTAAGTT
TTCTAAAGATTCTGGATCTATAAAAATCACTATGATTCATAAGACAAATCAATGGGTAGAAATAACAATTTGTGACAAAG
GTGCAGGTATCCCTTTGAGCGAACAAAAAAGAATTTTTCTAGATAGGGTTAGACTTCCCCAGACATCTGAAGGAACTTCA
GGATTTGGTATAGGCTTATCAGTATGCAGGAGAATAGTACAAGTCCATGGAGGAAGAATATGGGTGGTATCTGAAGTAGG
GGTGGGTTCCTGCTTCCATTTCACAGTTCCTGTGTGGCAAGGACAAAACAAAGAGCAACAAAACTTGACGAAAGGCTAG

Upstream 100 bases:

>100_bases
AAAAGTCCTATTTATTTAATAGCCTATCTGTAAAATAAAAAAAAATATCTTAAGGTGTTTATAAGGATTAACAGCTTTTC
AACACTTCAGAGGATTTCAT

Downstream 100 bases:

>100_bases
CCTTACTCTTAGTTTTTAATAAGCTGTTATGCTAATTTCCTGGCCCCATCGTCTAGAGGCCTAGGACACCTCCCTTTCAC
GGAGGCGACAGGGGTTCGAA

Product: adaptive-response sensory kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNDKKELKLILVAARNQLSSNDIKCLIAYLESDDCEFETSLQISEPKEQPELLELHRLVAIPALIKVSPAPKQIFAGSNI
FSQLQKWLPRWSQEGLTKNLGINLQPSKIDSTRTQKEFLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAVQSQKLGQIDISKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRIRNIEIDTDIP
SDLPSVFADQRRMRQVFLNLIENAIKFSKDSGSIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQGQNKEQQNLTKG

Sequences:

>Translated_372_residues
MNDKKELKLILVAARNQLSSNDIKCLIAYLESDDCEFETSLQISEPKEQPELLELHRLVAIPALIKVSPAPKQIFAGSNI
FSQLQKWLPRWSQEGLTKNLGINLQPSKIDSTRTQKEFLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAVQSQKLGQIDISKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRIRNIEIDTDIP
SDLPSVFADQRRMRQVFLNLIENAIKFSKDSGSIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQGQNKEQQNLTKG
>Mature_372_residues
MNDKKELKLILVAARNQLSSNDIKCLIAYLESDDCEFETSLQISEPKEQPELLELHRLVAIPALIKVSPAPKQIFAGSNI
FSQLQKWLPRWSQEGLTKNLGINLQPSKIDSTRTQKEFLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAVQSQKLGQIDISKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRIRNIEIDTDIP
SDLPSVFADQRRMRQVFLNLIENAIKFSKDSGSIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQGQNKEQQNLTKG

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=28.9256198347107, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=30.5555555555556, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=27.3913043478261, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI48994928, Length=254, Percent_Identity=27.9527559055118, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=26.8774703557312, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=245, Percent_Identity=30.2040816326531, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=26.171875, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=30.4721030042918, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=25.3275109170306, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=248, Percent_Identity=25.4032258064516, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=24.6753246753247, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788279, Length=237, Percent_Identity=27.8481012658228, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 42367; Mature: 42367

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKKELKLILVAARNQLSSNDIKCLIAYLESDDCEFETSLQISEPKEQPELLELHRLVA
CCCHHHEEEEEEEECCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHH
IPALIKVSPAPKQIFAGSNIFSQLQKWLPRWSQEGLTKNLGINLQPSKIDSTRTQKEFLL
HHHHEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHH
EDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAVQSQKLGQIDISKLQEVI
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHH
KRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRIRNIEIDTDIP
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCEEECCCCC
SDLPSVFADQRRMRQVFLNLIENAIKFSKDSGSIKITMIHKTNQWVEITICDKGAGIPLS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCC
EQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQ
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEC
GQNKEQQNLTKG
CCCCHHHCCCCC
>Mature Secondary Structure
MNDKKELKLILVAARNQLSSNDIKCLIAYLESDDCEFETSLQISEPKEQPELLELHRLVA
CCCHHHEEEEEEEECCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHH
IPALIKVSPAPKQIFAGSNIFSQLQKWLPRWSQEGLTKNLGINLQPSKIDSTRTQKEFLL
HHHHEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHH
EDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAVQSQKLGQIDISKLQEVI
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHH
KRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRIRNIEIDTDIP
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCEEECCCCC
SDLPSVFADQRRMRQVFLNLIENAIKFSKDSGSIKITMIHKTNQWVEITICDKGAGIPLS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCC
EQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQ
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEC
GQNKEQQNLTKG
CCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA