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The map label for this gene is aspC [H]

Identifier: 123968264

GI number: 123968264

Start: 647876

End: 649054

Strand: Reverse

Name: aspC [H]

Synonym: A9601_07291

Alternate gene names: 123968264

Gene position: 649054-647876 (Counterclockwise)

Preceding gene: 123968268

Following gene: 123968263

Centisome position: 38.87

GC content: 32.32

Gene sequence:

>1179_bases
ATGAGTCAAGTTAATTTATCTGATCGGGCTCTTTCAATTGAGCCTTCTCTTACATTACAGATAAGTGCTAAAGCAAATCA
ATTATCTGCAGAAGGAGTAGATATTTGCAATTTAAGTGCAGGTGAACCTGATTTTGATGCCCCAAAAGAAGTTATAGACG
CTACAAGTAAAGCTATATTTGATGGATTTACAAAGTACGGGCCAGCAGCGGGAAATTTAGATCTCCGAAAAGCAATTGCA
AATAAACTTCAAATTCAAAACGATTTAAATTATGAATTTGAAAATGTAATGGTCACAAATGGTGCTAAGCAAGCAATATA
TAATCTTTTCCAAGTATTGTTAAATACTGGAGACGAAGTTATTATTCCTTCTCCATATTGGTTAAGTTATCCCCAGATGG
TTAGATTGGCGGGTGGGAAGCCAATTTTTACAAATTCTTCTGCAGAAGATGGATTCAAAATAAATATAGAAGATTTGAAG
TCTAAAATCTCTTCAAAAACTAAATTTATAATTATCAATTCTCCTAATAACCCTACTGGAAGAGTTATGTCAAAGGAAGA
ATTATTACAAATTGCCGATTTAGCTAGAGAAAATCCAAATATTAATATTCTTTCTGATGAGATTTACGAACTAATCCTTA
AAAAAGAATTTAAACACTACAGTTTATCTTCATTAGCAAATGACTTAAAAGATAGAATTTTTATAATAAATGGGTTTGCG
AAAGGATGGGCTATGACTGGCTGGAGGATAGGTTATTTAGTAGGTCCCAAAGATGTAATCAAAGCATCCTCAGCATTACA
AAGTCAAAGTACAAGTAATGTTTGCTCTTTTGTTCAAAAAGGTGCTTTAGAGGCTTTAAAAATTAATAATGAGTTTTTCT
CAATGATAAATAGCCATTATGATCAAAGAAGAAGACTTCTCTATGAGGGCCTTAATAATATAAATGGGATTTATATTGAA
GAACCTAACGGAGCATTTTACGCATTTCCAAAATTACCCAACTCCTCAATTACTTCCGTTGATTTCTGCAATAAAGCTCT
TCAAGATTACGGATTAGTTGTTGTACCTGGGAAAGCTTTTGGAGCTGATCAATGTATAAGAATATCTTGTGCAGCTTCAG
AAATTAAAATAAAAGATGGACTACATAGACTTGAAAAAGCAATCTCTGAATACTATTAA

Upstream 100 bases:

>100_bases
AAGAAAATGAACTAAATTAAACCATAGTGTGATAGTTTTATTTATTCTTAATTTATGCATTTGTCATTATTAAAAGTCAT
ATTTGAAAAGTCATAAGTCA

Downstream 100 bases:

>100_bases
TTTAACAAAGTTATGTTTAATTTAAAAAATTTCCTAATAAGTTCATATCTATTATTTTCTGTTTTTTCATCACCTGTATT
TTCAAATCCCAAAGTTTTAA

Product: aminotransferases class-I

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIDATSKAIFDGFTKYGPAAGNLDLRKAIA
NKLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEVIIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLK
SKISSKTKFIIINSPNNPTGRVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKDRIFIINGFA
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHYDQRRRLLYEGLNNINGIYIE
EPNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAFGADQCIRISCAASEIKIKDGLHRLEKAISEYY

Sequences:

>Translated_392_residues
MSQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIDATSKAIFDGFTKYGPAAGNLDLRKAIA
NKLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEVIIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLK
SKISSKTKFIIINSPNNPTGRVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKDRIFIINGFA
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHYDQRRRLLYEGLNNINGIYIE
EPNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAFGADQCIRISCAASEIKIKDGLHRLEKAISEYY
>Mature_391_residues
SQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIDATSKAIFDGFTKYGPAAGNLDLRKAIAN
KLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEVIIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLKS
KISSKTKFIIINSPNNPTGRVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKDRIFIINGFAK
GWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHYDQRRRLLYEGLNNINGIYIEE
PNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAFGADQCIRISCAASEIKIKDGLHRLEKAISEYY

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=25.8312020460358, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=25.8312020460358, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI56713254, Length=314, Percent_Identity=30.2547770700637, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI56713256, Length=314, Percent_Identity=30.2547770700637, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=27.3209549071618, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI169881281, Length=319, Percent_Identity=23.8244514106583, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI187936925, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI14211921, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=320, Percent_Identity=32.5, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=28.3819628647215, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788722, Length=379, Percent_Identity=25.8575197889182, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790797, Length=362, Percent_Identity=23.2044198895028, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994949, Length=370, Percent_Identity=23.5135135135135, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=336, Percent_Identity=27.9761904761905, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71994472, Length=283, Percent_Identity=30.0353356890459, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=283, Percent_Identity=30.0353356890459, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=250, Percent_Identity=32.4, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=400, Percent_Identity=24.75, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323118, Length=340, Percent_Identity=22.9411764705882, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=311, Percent_Identity=25.08038585209, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28573069, Length=349, Percent_Identity=26.647564469914, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24646114, Length=349, Percent_Identity=26.647564469914, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28573067, Length=349, Percent_Identity=26.647564469914, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28573065, Length=349, Percent_Identity=26.647564469914, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=22.0159151193634, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43426; Mature: 43295

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIDATSKAIF
CCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
DGFTKYGPAAGNLDLRKAIANKLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEV
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECEEEEECCHHHHHHHHHHHHHCCCCCE
IIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLKSKISSKTKFIIINSPNNPTG
EECCCCCCCCHHHHHHCCCCEEECCCCCCCCEEEEHHHHHHHHCCCEEEEEEECCCCCCC
RVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKDRIFIINGFA
CCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECC
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHY
CCEECCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEECHHHHHHHHHHH
DQRRRLLYEGLNNINGIYIEEPNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAF
HHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEECCCCC
GADQCIRISCAASEIKIKDGLHRLEKAISEYY
CCCCEEEEEECCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIDATSKAIF
CCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
DGFTKYGPAAGNLDLRKAIANKLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEV
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECEEEEECCHHHHHHHHHHHHHCCCCCE
IIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLKSKISSKTKFIIINSPNNPTG
EECCCCCCCCHHHHHHCCCCEEECCCCCCCCEEEEHHHHHHHHCCCEEEEEEECCCCCCC
RVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKDRIFIINGFA
CCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECC
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHY
CCEECCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEECHHHHHHHHHHH
DQRRRLLYEGLNNINGIYIEEPNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAF
HHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEECCCCC
GADQCIRISCAASEIKIKDGLHRLEKAISEYY
CCCCEEEEEECCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]