Click here to switch to the map view.

The map label for this gene is nadA [H]

Identifier: 123968268

GI number: 123968268

Start: 652364

End: 653278

Strand: Reverse

Name: nadA [H]

Synonym: A9601_07331

Alternate gene names: 123968268

Gene position: 653278-652364 (Counterclockwise)

Preceding gene: 123968270

Following gene: 123968264

Centisome position: 39.12

GC content: 33.33

Gene sequence:

>915_bases
TTGATTTCTGAAATAAAGGAGCGTTGCAAAAAAGCTAATGCAATTATTCTTGCGCACTATTATCAAGCACCAGAGATTCA
GGAAATTGCAGATTTTATTGGAGATTCATTAGATCTATCTAAGAAAGCTGCAAATAATGACGCAGATATAATAATTTTTT
GCGGTGTGCACTTTATGGCCGAAACCGCAAAAATACTTAGCCCTAATAAAACAGTCCTACTACCAGATATTGACGCAGGA
TGCTCATTAGCAGACGATTGTCCTTCAGATAAATTTCAAAAATTCAGGGAAGAAAATCCAGATCACTATGTCGTAAGTTA
TATAAATTGCACTGCAGAAGTAAAAGCTCAAAGTGATCTGATATGTACAAGCAGTAATGCAGTCTCATTAATTAAAAAGA
TACCTGAAGATAAAAAGATAATATTTGCGCCAGATCAGAACCTTGGGAGATGGGTACAGAAAAATTCAGGAAGAGATCTT
AAATTATGGCCTGGCAGCTGCATTGTTCATGAATCATTTAGTGAAGAAGCACTTCTAAAATTAAAATATCAAAATCCAGG
ATCAAAAGTAATTGCTCATCCTGAATGTAGTCAAAATTTACTAATTCTCTCAGACTTTATTGGATCAACAAGTAAGCTGC
TTGATTTCGTAAGTAAAGATCCATCTAAAACTTACATGGTACTAACTGAACCTGGAATAATTCATCAAATGAAAAAGAAA
GAACCTAATAAAATTTTTATTGAAGTCCCAGATGTAGAAGGTTGTAAATGTAACGAGTGTCCGTATATGAAATTAAATAC
TTTAGAAAAAATTCTTGATTGTTTGAAAAATAATTCCCCGTCTATCGAACTAGACCCAGAAATAATAAGAAGAGCCTATG
TGCCAATAAAGAGAATGCTGGATATGAGTAATTAA

Upstream 100 bases:

>100_bases
TTTTTCTGTTTAAAGGCATATAATCTATATAGATATATTCTAAATCCTGACCAGTATAACTTCTACTGCAAAACAGAAAT
CAGTTCAAAACGAAGAGGAT

Downstream 100 bases:

>100_bases
TTTAATGAAAATACTTTATCTTCCTTATTAATTTTTAGGAATGCATTAAGGTTTGTGGTGTCGGGCTTAAATTCGCTTAT
CTGATTCTTTCTATTAATTA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSKKAANNDADIIIFCGVHFMAETAKILSPNKTVLLPDIDAG
CSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDLICTSSNAVSLIKKIPEDKKIIFAPDQNLGRWVQKNSGRDL
KLWPGSCIVHESFSEEALLKLKYQNPGSKVIAHPECSQNLLILSDFIGSTSKLLDFVSKDPSKTYMVLTEPGIIHQMKKK
EPNKIFIEVPDVEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEIIRRAYVPIKRMLDMSN

Sequences:

>Translated_304_residues
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSKKAANNDADIIIFCGVHFMAETAKILSPNKTVLLPDIDAG
CSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDLICTSSNAVSLIKKIPEDKKIIFAPDQNLGRWVQKNSGRDL
KLWPGSCIVHESFSEEALLKLKYQNPGSKVIAHPECSQNLLILSDFIGSTSKLLDFVSKDPSKTYMVLTEPGIIHQMKKK
EPNKIFIEVPDVEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEIIRRAYVPIKRMLDMSN
>Mature_304_residues
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSKKAANNDADIIIFCGVHFMAETAKILSPNKTVLLPDIDAG
CSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDLICTSSNAVSLIKKIPEDKKIIFAPDQNLGRWVQKNSGRDL
KLWPGSCIVHESFSEEALLKLKYQNPGSKVIAHPECSQNLLILSDFIGSTSKLLDFVSKDPSKTYMVLTEPGIIHQMKKK
EPNKIFIEVPDVEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEIIRRAYVPIKRMLDMSN

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=311, Percent_Identity=40.5144694533762, Blast_Score=248, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34156; Mature: 34156

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSKKAANNDADIIIFCGVHFMA
CCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCCCHHHCCCCCCCEEEEECHHHHH
ETAKILSPNKTVLLPDIDAGCSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDL
HHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCE
ICTSSNAVSLIKKIPEDKKIIFAPDQNLGRWVQKNSGRDLKLWPGSCIVHESFSEEALLK
EEECCHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEEEECCCCEEEECCCCCCEEEE
LKYQNPGSKVIAHPECSQNLLILSDFIGSTSKLLDFVSKDPSKTYMVLTEPGIIHQMKKK
EEECCCCCCEEECCCCCCCEEEEEHHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHCC
EPNKIFIEVPDVEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEIIRRAYVPIKRML
CCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHH
DMSN
CCCC
>Mature Secondary Structure
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSKKAANNDADIIIFCGVHFMA
CCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCCCHHHCCCCCCCEEEEECHHHHH
ETAKILSPNKTVLLPDIDAGCSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDL
HHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCE
ICTSSNAVSLIKKIPEDKKIIFAPDQNLGRWVQKNSGRDLKLWPGSCIVHESFSEEALLK
EEECCHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEEEECCCCEEEECCCCCCEEEE
LKYQNPGSKVIAHPECSQNLLILSDFIGSTSKLLDFVSKDPSKTYMVLTEPGIIHQMKKK
EEECCCCCCEEECCCCCCCEEEEEHHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHCC
EPNKIFIEVPDVEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEIIRRAYVPIKRML
CCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHH
DMSN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA