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The map label for this gene is mscS [C]

Identifier: 123968226

GI number: 123968226

Start: 613875

End: 614906

Strand: Reverse

Name: mscS [C]

Synonym: A9601_06911

Alternate gene names: 123968226

Gene position: 614906-613875 (Counterclockwise)

Preceding gene: 123968227

Following gene: 123968224

Centisome position: 36.82

GC content: 30.52

Gene sequence:

>1032_bases
ATGAAATTAGTTACTGAAAACTTCCTTCTGGCAATATCTATTTTTTTTATTGGAATTTTATTGTCGATAATAATTTCAAA
ACTTTCAAAAATATTCTTCAAAAAGATCTCCAAGCGTACAAAGACAAATTTTGATGATTTTATTTTTGAGGTCATCTCTG
GAATTGTTAAACCAATAGGTTTCCTTCTCTCATTTTATTTTTCAATTGACTACTTTTTTGCTGATGAAATAACTTTTATC
TCTGTATTATTAAATATTCTGAAATTATTCATATTGATAATAATTATAAAAGCTCTCAATAAAGTTTTAATAAGATCTTT
AACAGAATCGACATCGAAAATTAATGATTCCTCAATCAGTTCAATGATATCTTCACTTACTCCTTTAATAAAAGCATTAA
CATGGACTATTGGTTCAATCTTTTTCTTACAAAATATAGGTGTTCAAATGACCGCAATTTGGGCTCTCCTAAGTGCAGGG
GGTATTGGAGCAGGATTAGCTTTGAAAGACCCAGTTCAGGAGTTTTTTGAATACATAACAATTTTGCTTGATAAACCTTT
TCAAAAAGGTGAGTTTATAAAATCTGATGGCGTCCTTGGAATGGTTGAGAGGGTCGGAGTAAGGTCCTCAAGAATAAGAA
GTATCAATGGAGAAGTAATAGTAATGAGCAACAGCGCCCTTACAAATGGAATAATTTCAAATTACGCACAAATGGAAAAA
AGAAGGTTAGTGCATAAATTAGGAGTTGTTTATGAAACCTCGCCAAAACTTATGAAATTGATTCCAATAATAATAAAAAA
AATAGTTGAAGAGACAAAAGATGCCTCTTTTGATAGGTGTCATTTCACAGACTTTGGCGACTTCAGTCTTAATTTCGAAC
TAGTTTATTACATCCCAACAAATAATTATCTCGCTGCAATGGAAGCTCAACAATCTATAAATTTAAGAATTATTGAGGAA
TTTGCGGTTAATAATATAGAGTTTGCATTCCCAACACAAACCTTAAATATTGAAAGTAACAAAGCCAAATGA

Upstream 100 bases:

>100_bases
TAGAAATATAATAATTAGATAAAGAGAAAACAAGACTGGTCTGTAATCTAGAGATAATTTAAAATTTTATTAAAGATAAA
TTTTGAAGTTCTATTTGAAT

Downstream 100 bases:

>100_bases
TCTACAAATCTCTTCACTTAAAATCCAGAGTTTTGAAGCCAACTCAGAATTATTTGCCTCATCACTAACCTTACTTTCAA
CTAATTTATGTTTTTTAAAA

Product: small mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKLVTENFLLAISIFFIGILLSIIISKLSKIFFKKISKRTKTNFDDFIFEVISGIVKPIGFLLSFYFSIDYFFADEITFI
SVLLNILKLFILIIIIKALNKVLIRSLTESTSKINDSSISSMISSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAG
GIGAGLALKDPVQEFFEYITILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPTNNYLAAMEAQQSINLRIIEE
FAVNNIEFAFPTQTLNIESNKAK

Sequences:

>Translated_343_residues
MKLVTENFLLAISIFFIGILLSIIISKLSKIFFKKISKRTKTNFDDFIFEVISGIVKPIGFLLSFYFSIDYFFADEITFI
SVLLNILKLFILIIIIKALNKVLIRSLTESTSKINDSSISSMISSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAG
GIGAGLALKDPVQEFFEYITILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPTNNYLAAMEAQQSINLRIIEE
FAVNNIEFAFPTQTLNIESNKAK
>Mature_343_residues
MKLVTENFLLAISIFFIGILLSIIISKLSKIFFKKISKRTKTNFDDFIFEVISGIVKPIGFLLSFYFSIDYFFADEITFI
SVLLNILKLFILIIIIKALNKVLIRSLTESTSKINDSSISSMISSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAG
GIGAGLALKDPVQEFFEYITILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPTNNYLAAMEAQQSINLRIIEE
FAVNNIEFAFPTQTLNIESNKAK

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=208, Percent_Identity=26.4423076923077, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789291, Length=282, Percent_Identity=25.886524822695, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 38673; Mature: 38673

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVTENFLLAISIFFIGILLSIIISKLSKIFFKKISKRTKTNFDDFIFEVISGIVKPIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLLSFYFSIDYFFADEITFISVLLNILKLFILIIIIKALNKVLIRSLTESTSKINDSSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SMISSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAGGIGAGLALKDPVQEFFEYIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
HHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECC
NNYLAAMEAQQSINLRIIEEFAVNNIEFAFPTQTLNIESNKAK
CCEEEEEHHHHCCCCEEEHHHHCCCEEEEECCEEEECCCCCCC
>Mature Secondary Structure
MKLVTENFLLAISIFFIGILLSIIISKLSKIFFKKISKRTKTNFDDFIFEVISGIVKPIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLLSFYFSIDYFFADEITFISVLLNILKLFILIIIIKALNKVLIRSLTESTSKINDSSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SMISSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAGGIGAGLALKDPVQEFFEYIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
HHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECC
NNYLAAMEAQQSINLRIIEEFAVNNIEFAFPTQTLNIESNKAK
CCEEEEEHHHHCCCCEEEHHHHCCCEEEEECCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]