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The map label for this gene is pncA [C]

Identifier: 123968227

GI number: 123968227

Start: 614985

End: 615551

Strand: Reverse

Name: pncA [C]

Synonym: A9601_06921

Alternate gene names: 123968227

Gene position: 615551-614985 (Counterclockwise)

Preceding gene: 123968229

Following gene: 123968226

Centisome position: 36.86

GC content: 29.28

Gene sequence:

>567_bases
ATGAAGGGGCATGAAAAATCTTCTGACAAACTATCACCAAAAGTGAATGCTTTACTAATCATAGATGTTCAGGAAAAAAT
TATAAGAGCAATATTTAACAAAGATTCAATAACCAAAAACATCAAAAAGCTAATAGATGCCTACCAAATTTTAGAAGAAA
ACATTTTTTTATCTGAACAGAACCCATTCAAATTGGGTGCAACGGTACCTGAATTGTTGCCCAAAAATGGATTTAAAAAA
ATTGAGAAAATGGATTTTAGCTTAGCTAACATACAAGAATTTTTAGAAGAACTTAAAAATAAGAAAATTACAAATTTGAT
AGTTTGTGGTATCGAAACGCATATTTGTATTCAACAAACAGCCTTAGATTGTTTAGAAAAAGGATTTGAAGTTATTCTCG
TATCAGATGCTATGAGCAGTCGAAATAGGGTAGATCATGAAATAGCATTGCAGAGAATGATTCAGAAGGGAGCGATCTTA
ACAACTACTGAATCAATAATTTTTGAATTATGCAAAACTGCGGATAGAAAAGAATTTAAAGAAATTAGAAATATAATAAT
TAGATAA

Upstream 100 bases:

>100_bases
TCAATAATAACTCTAGATGAGATTAAAACAACTTTATGATTTAAAATGTTTACTAAAGTTGTTCAAAATACTATGTTGAA
TATATCTTTAAATACAAATA

Downstream 100 bases:

>100_bases
AGAGAAAACAAGACTGGTCTGTAATCTAGAGATAATTTAAAATTTTATTAAAGATAAATTTTGAAGTTCTATTTGAATAT
GAAATTAGTTACTGAAAACT

Product: isochorismatase hydrolase family protein

Products: NA

Alternate protein names: Isochorismatase Family Protein; Isochorismatase Hydrolase Family Protein; Isochorismatase Superfamily Hydrolase; Nicotinamidase-Like Amidase; Amidase; Isochorismatase Family Hydrolase; Isochorismatase Domain-Containing; Hydrolase; Hydrolase Isochorismatase Family; Amidohydrolase; Hydrolase Isochorismatase; Amidase Related Nicotinamidase; YcaC Like Amidohydrolase; Isochorismatase Family; Nicotinamidase; YcaC-Related Amidohydrolase; Isochorismatase Domain-Containing A; Isochorismatase Hydrolase Family; Nicotinamidase-Related Amidase

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKGHEKSSDKLSPKVNALLIIDVQEKIIRAIFNKDSITKNIKKLIDAYQILEENIFLSEQNPFKLGATVPELLPKNGFKK
IEKMDFSLANIQEFLEELKNKKITNLIVCGIETHICIQQTALDCLEKGFEVILVSDAMSSRNRVDHEIALQRMIQKGAIL
TTTESIIFELCKTADRKEFKEIRNIIIR

Sequences:

>Translated_188_residues
MKGHEKSSDKLSPKVNALLIIDVQEKIIRAIFNKDSITKNIKKLIDAYQILEENIFLSEQNPFKLGATVPELLPKNGFKK
IEKMDFSLANIQEFLEELKNKKITNLIVCGIETHICIQQTALDCLEKGFEVILVSDAMSSRNRVDHEIALQRMIQKGAIL
TTTESIIFELCKTADRKEFKEIRNIIIR
>Mature_188_residues
MKGHEKSSDKLSPKVNALLIIDVQEKIIRAIFNKDSITKNIKKLIDAYQILEENIFLSEQNPFKLGATVPELLPKNGFKK
IEKMDFSLANIQEFLEELKNKKITNLIVCGIETHICIQQTALDCLEKGFEVILVSDAMSSRNRVDHEIALQRMIQKGAIL
TTTESIIFELCKTADRKEFKEIRNIIIR

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI209969695, Length=187, Percent_Identity=35.8288770053476, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI13376007, Length=203, Percent_Identity=33.4975369458128, Blast_Score=110, Evalue=5e-25,
Organism=Homo sapiens, GI103471987, Length=184, Percent_Identity=34.2391304347826, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17540156, Length=182, Percent_Identity=39.010989010989, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI19922924, Length=178, Percent_Identity=34.2696629213483, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21357489, Length=179, Percent_Identity=33.5195530726257, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21530; Mature: 21530

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGHEKSSDKLSPKVNALLIIDVQEKIIRAIFNKDSITKNIKKLIDAYQILEENIFLSEQ
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCEECCC
NPFKLGATVPELLPKNGFKKIEKMDFSLANIQEFLEELKNKKITNLIVCGIETHICIQQT
CCCCCCCCCHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHH
ALDCLEKGFEVILVSDAMSSRNRVDHEIALQRMIQKGAILTTTESIIFELCKTADRKEFK
HHHHHHCCCEEEEEECHHHHHHCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHHH
EIRNIIIR
HHHHHHCC
>Mature Secondary Structure
MKGHEKSSDKLSPKVNALLIIDVQEKIIRAIFNKDSITKNIKKLIDAYQILEENIFLSEQ
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCEECCC
NPFKLGATVPELLPKNGFKKIEKMDFSLANIQEFLEELKNKKITNLIVCGIETHICIQQT
CCCCCCCCCHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHH
ALDCLEKGFEVILVSDAMSSRNRVDHEIALQRMIQKGAILTTTESIIFELCKTADRKEFK
HHHHHHCCCEEEEEECHHHHHHCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHHH
EIRNIIIR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA