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The map label for this gene is trpS [H]

Identifier: 123968189

GI number: 123968189

Start: 578118

End: 579134

Strand: Reverse

Name: trpS [H]

Synonym: A9601_06541

Alternate gene names: 123968189

Gene position: 579134-578118 (Counterclockwise)

Preceding gene: 123968190

Following gene: 123968188

Centisome position: 34.68

GC content: 31.96

Gene sequence:

>1017_bases
ATGGCAAATAAAAAAAGAATTCTTTCGGGAGTTCAACCAACTGGTGATTTACATATTGGGAATTGGCTTGGGGCCATAAA
TAATTGGGTTGAGCTTCAAGATCAATATGAAACATTTTTATGTGTAGTTGATTTGCACGCAATAACAGCCTCATATAATC
CCAAAGAATTATCTAAAAACACGATCTCTACAGCGGCTTTGTACGTCGCTTGTGGTATAGATCCCAATATATGCTCAATT
TTTGTCCAAAGTCAGATTTCAGCGCATTCAGAACTTTGTTGGATATTAAATTGTATGACCCCAATAAATTGGATGGAAAG
AATGATTCAATTTAAAGAAAAATCCATACAACAAGGTAATAATGTATCTATTGGATTATTTGACTATCCAATACTTATGG
CGGCAGACATCCTTCTTTATAATGCTGACTTCGTACCAGTAGGTGAGGATCAAAAACAACATCTTGAACTTGCGAGAGAT
ATTGCACAACAGAGAATTAATGCCAGATTTAGTAAGGATAAAAATATTTTAAAGATCCCTCAACCAATCATCATGAAGAA
TGGTTCAAAAATAATGAGTTTAATTGATGGTTCAAAAAAGATGAGCAAAAGTGATCCCAATGAGGGCAGTCGCATTAACT
TATTAGATCCTCCTGAAATAATCACAAAAAAAATTAAAAGAGCAAAAAGTGACAGTTCTGTTGGAATTGAATTTAACAAC
CCTGAGAGGCCAGAATCTAAAAATCTATTGATGATTTATTCAATATTATCTGGCAAAGAAATTTCTCAATGTGAAAATGA
ATTCTTAGAGACTGGATGGGGGACATTTAAAAAATTAATTACTGAACAACTTATTGAATCATTAGAACCTATTCAGAAAA
AATATAAATTATTAATTAATGATCCCTATCAACTAAATAAAATCCTTAATGAAGGGAAGGAAAAAGCTGAAGATTTAGCG
AATCAGACTTTAAAAAGAGTTAAATCAAAATTGGGGTTTTTTGAAATGGAGAAATAA

Upstream 100 bases:

>100_bases
AATTCTTATGAAGAAAAGACAAAAACAGCACCTGACCCTTTTGCAAGACCTGTAAAAAGTACATCAACTGAAGAGATCCA
ATCTAGCGAAGTAGAAGAGG

Downstream 100 bases:

>100_bases
ATTATGCCAATAATTACTTTGCCTGATGGTTCAAAAAAGGTTTTCGAAAAATCTGTAACTATTCTAGAAATTGCTCAGAG
TATAGGCGCTGGATTAGCTA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MANKKRILSGVQPTGDLHIGNWLGAINNWVELQDQYETFLCVVDLHAITASYNPKELSKNTISTAALYVACGIDPNICSI
FVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGNNVSIGLFDYPILMAADILLYNADFVPVGEDQKQHLELARD
IAQQRINARFSKDKNILKIPQPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSVGIEFNN
PERPESKNLLMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLINDPYQLNKILNEGKEKAEDLA
NQTLKRVKSKLGFFEMEK

Sequences:

>Translated_338_residues
MANKKRILSGVQPTGDLHIGNWLGAINNWVELQDQYETFLCVVDLHAITASYNPKELSKNTISTAALYVACGIDPNICSI
FVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGNNVSIGLFDYPILMAADILLYNADFVPVGEDQKQHLELARD
IAQQRINARFSKDKNILKIPQPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSVGIEFNN
PERPESKNLLMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLINDPYQLNKILNEGKEKAEDLA
NQTLKRVKSKLGFFEMEK
>Mature_337_residues
ANKKRILSGVQPTGDLHIGNWLGAINNWVELQDQYETFLCVVDLHAITASYNPKELSKNTISTAALYVACGIDPNICSIF
VQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGNNVSIGLFDYPILMAADILLYNADFVPVGEDQKQHLELARDI
AQQRINARFSKDKNILKIPQPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSVGIEFNNP
ERPESKNLLMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLINDPYQLNKILNEGKEKAEDLAN
QTLKRVKSKLGFFEMEK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=37.2372372372372, Blast_Score=248, Evalue=4e-66,
Organism=Homo sapiens, GI41352700, Length=162, Percent_Identity=49.3827160493827, Blast_Score=180, Evalue=2e-45,
Organism=Escherichia coli, GI1789786, Length=329, Percent_Identity=45.5927051671732, Blast_Score=303, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI71982800, Length=337, Percent_Identity=34.4213649851632, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71982793, Length=337, Percent_Identity=34.4213649851632, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6320474, Length=348, Percent_Identity=37.9310344827586, Blast_Score=206, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=39.9399399399399, Blast_Score=251, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38353; Mature: 38222

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKKRILSGVQPTGDLHIGNWLGAINNWVELQDQYETFLCVVDLHAITASYNPKELSKN
CCCHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
TISTAALYVACGIDPNICSIFVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGN
HHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
NVSIGLFDYPILMAADILLYNADFVPVGEDQKQHLELARDIAQQRINARFSKDKNILKIP
CEEEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
QPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSVGIEFNN
CHHHHCCCHHHHHHHCCCHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECC
PERPESKNLLMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLIN
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPYQLNKILNEGKEKAEDLANQTLKRVKSKLGFFEMEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure 
ANKKRILSGVQPTGDLHIGNWLGAINNWVELQDQYETFLCVVDLHAITASYNPKELSKN
CCHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
TISTAALYVACGIDPNICSIFVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGN
HHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
NVSIGLFDYPILMAADILLYNADFVPVGEDQKQHLELARDIAQQRINARFSKDKNILKIP
CEEEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
QPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSVGIEFNN
CHHHHCCCHHHHHHHCCCHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECC
PERPESKNLLMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLIN
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPYQLNKILNEGKEKAEDLANQTLKRVKSKLGFFEMEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]